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Details of CancerPDF entry with Sequence KGNSGEPGAPGSKGDTGAKGEPGPVG
Primary information
sequence IDSeq_4188
Peptide sequenceKGNSGEPGAPGSKGDTGAKGEPGPVG
CancerPDF_ID CancerPDF_ID3415, CancerPDF_ID5595, CancerPDF_ID10919,
PMID27186406,24982608,21805675
Protein NameCollagen type a1,Collagen alpha-1(I) chain,Collagen alpha-1(I) chain
UniprotKB Entry NameCO4A1_HUMAN,CO1A1_HUMAN,CO1A1_HUMAN
FluidUrine,Urine,Urine
M/ZNA,NA,2356.0992
ChargeNA,NA,NA
Mass (in Da)NA,NA,NA
fdrNA,NA,NA
Profiling TechniqueLC-MS,Nano-LC-MS,MALDI-TOF
Peptide Identification techniqueSRM (Selective reaction Measurement),MS/MS,MALDI-TOF-MS
Quantification TechniqueNA,NA,NA
Labelled/Label FreeLabelled,Label Free,Label Free
FDRNA,0.01,1
CancerPDF_ID CancerPDF_ID3415, CancerPDF_ID5595, CancerPDF_ID10919,
p-Valueless than 0.001,NA,NA
SoftwareNA,"GPM search engine, MASCOT",NA
Length26,26,26
Cancer TypeCRLM( Colorectal liver metastses),Ovarian cancer,Muscle-invasive bladder cancer
DatabaseNA,IPI 3.71 Human Database ,SwissProt Database
Modification"Hydroxylation at 6,21 residue",NA,"Oxidation: 7, 10, 22"
Number of Patients100 patients,6 Ovarian cancer patients and 6 normal individuals,751 bladder cancer and 127 control
RegulationNA,Uniquely present in case of urine of ovarian cancer patients,Differentially expressed between cancer vs normal samples
ValidationCross-validation,NA,Mann-Whitney tests and areas under receiver-operator characteristic
Sensitivity0.85,NA,NA
Specificity0.84,NA,NA
AccuracyNA,NA,NA
Peptide AtlasNA
IEDB
Primary information
sequence IDSeq_4189
Peptide sequenceKGNSGEPGApGSKGDTGAKGEPGpVG
CancerPDF_ID CancerPDF_ID3737,
PMID27026199
Protein NameCollagen alpha-1(I) chain
UniprotKB Entry NameCO1A1_HUMAN
FluidUrine
fdr2339.1
Profiling Technique"CE-MS, Micro-TOF-MS"
Peptide Identification techniqueMS-MS
Labelled/Label FreeLabel Free
CancerPDF_ID CancerPDF_ID3737,
p-Valueless than 0.05
SoftwareProteome Discoverer 1.2
Length26
Cancer TypeBladder cancer
DatabaseUniprot Human non-redundant Database
Modificationp:Hydroxy-Proline
Number of Patients 425 for training(109 patients with Recurrent UBC cases and 316 negative for recurrence controls) and 211 for validation (55 UBC recurrent cases and 156 recurrent controls)
RegulationDifferentially expressed between recurrence of UBC vs recurrence control
ValidationIndependent Validation
SensitivityFor testing dataset 88%
SpecificityFor testing dataset 51%
AccuracyNA
Peptide AtlasNA
IEDBNA
Primary information
sequence IDSeq_4190
Peptide sequenceKGNSGEpGAPGSKGDTGAKGEpGpVG
CancerPDF_ID CancerPDF_ID3742,
PMID27026199
Protein NameCollagen alpha-1(I) chain
UniprotKB Entry NameCO1A1_HUMAN
FluidUrine
fdr2355.09
Profiling Technique"CE-MS, Micro-TOF-MS"
Peptide Identification techniqueMS-MS
Labelled/Label FreeLabel Free
CancerPDF_ID CancerPDF_ID3742,
p-Valueless than 0.01
SoftwareProteome Discoverer 1.2
Length26
Cancer TypeBladder cancer
DatabaseUniprot Human non-redundant Database
Modificationp:Hydroxy-Proline
Number of Patients 425 for training(109 patients with Recurrent UBC cases and 316 negative for recurrence controls) and 211 for validation (55 UBC recurrent cases and 156 recurrent controls)
RegulationDifferentially expressed between recurrence of UBC vs recurrence control
ValidationIndependent Validation
SensitivityFor testing dataset 88%
SpecificityFor testing dataset 51%
AccuracyNA
Peptide AtlasNA
IEDBNA
Primary information
sequence IDSeq_4191
Peptide sequenceKGNSGEpGApGSKGDTGAKGEpGpVG
CancerPDF_ID CancerPDF_ID3744,
PMID27026199
Protein NameCollagen alpha-1(I) chain
UniprotKB Entry NameCO1A1_HUMAN
FluidUrine
fdr2371.09
Profiling Technique"CE-MS, Micro-TOF-MS"
Peptide Identification techniqueMS-MS
Labelled/Label FreeLabel Free
CancerPDF_ID CancerPDF_ID3744,
p-Valueless than 0.01
SoftwareProteome Discoverer 1.2
Length26
Cancer TypeBladder cancer
DatabaseUniprot Human non-redundant Database
Modificationp:Hydroxy-Proline
Number of Patients 425 for training(109 patients with Recurrent UBC cases and 316 negative for recurrence controls) and 211 for validation (55 UBC recurrent cases and 156 recurrent controls)
RegulationDifferentially expressed between recurrence of UBC vs recurrence control
ValidationIndependent Validation
SensitivityFor testing dataset 88%
SpecificityFor testing dataset 51%
AccuracyNA
Peptide AtlasNA
IEDBNA