| Primary information |
|---|
| sequence ID | Seq_3904 |
| Peptide sequence | ISASAEELRQRLAPLAEDVRGNL |
| CancerPDF_ID | CancerPDF_ID78, CancerPDF_ID1077, CancerPDF_ID8581, |
| PMID | 16896061,16395409,23667664 |
| Protein Name | Apolipoprotein A-IV,Apolipoprotein A-IV,Aplipoprotein A-IV |
| UniprotKB Entry Name | APOA4_HUMAN,APOA4_HUMAN,APOA4_HUMAN |
| Fluid | Serum,Serum,Serum |
| M/Z | 2508.16,2508.16,2507.35 |
| Charge | 1,1,1 |
| Mass (in Da) | 2508.35,NA,2509.83 |
| fdr | NA,NA,NA |
| Profiling Technique | MALDI-TOF,MALDI-TOF,MALDI-TOF |
| Peptide Identification technique | Q/TOF MS/MS,Q/TOF/TOF and LC-MS/MS,FT-ICR MS/MS + nano-HPLC |
| Quantification Technique | NA,NA,NA |
| Labelled/Label Free | Label Free,Label Free,Label Free |
| FDR | NA,less than 1 “5,NA |
| CancerPDF_ID | CancerPDF_ID78, CancerPDF_ID1077, CancerPDF_ID8581, |
| p-Value | 1.00E-05,5.60E-14,NA |
| Software | MASCOT,MASCOT (v 2.0.04 for Windows),MASCOT |
| Length | 23,23,23 |
| Cancer Type | Metastatic thyroid carcinomas,"Advanced Prostate, Breast and Bladder cancer","Breast cancer, Lung cancer, Rectal cancer" |
| Database | NCBI refseq Protein Database,NCBI refseq Protein Database,NA |
| Modification | NA,NA,NA |
| Number of Patients | 40 metastatic thyroid carcinoma patients and 40 normal for training phase and 10 metastatic thyroid carcinoma and 10 normal individuals for independent validation,"Advanced prostate (n = 32), breast (n = 21), and bladder (n = 20) cancer, 33 healthy in training test set, In validation set 41 independent serum samples from patients with advanced prostate cancer (prostate 2 [PR2])","Breast Cancer =84, lung cancer= 70, Rectal cancer = 30patients; 500 healthy" |
| Regulation | NA,"Upregulated in cancer vs normal with Ratio of median intensity (patients/Controls) =1.38, 1.2 and 7.96 in prostate, bladder and breast cancer respectively",NA |
| Validation | Independent validation,Independent validation,NA |
| Sensitivity | 95% on independent dataset,97.5% on independent validation dataset,NA |
| Specificity | 95% on independent dataset,NA,NA |
| Accuracy | NA,97.5 % on validation dataset,NA |
| Peptide Atlas | NA |
| IEDB | |