| Primary information |
|---|
| sequence ID | Seq_3527 |
| Peptide sequence | HRHPDEAAFFDTASTGK |
| CancerPDF_ID | CancerPDF_ID667, CancerPDF_ID1315, CancerPDF_ID2359, CancerPDF_ID9745, CancerPDF_ID11598, CancerPDF_ID12756, |
| PMID | 19795908,21136997,21136997,21533267,26992070,26282206 |
| Protein Name | Fibrinogen alpha chain,Fibrinogen alpha,Fibrinogen alpha,Fibrinogen alpha chain,Fibrinogen alpha chain,"FGA, Isoform 2 of Fibrinogen alpha chain" |
| UniprotKB Entry Name | FIBA_HUMAN,FIBA_HUMAN,FIBA_HUMAN,FIBA_HUMAN,FIBA_HUMAN,FIBA_HUMAN |
| Fluid | Plasma,Serum,Plasma,Serum,Serum,Serum |
| M/Z | "943.94, 629.63",1885.87072,1885.8707,629.62,1885.8707,1889.4 |
| Charge | "2, 3",1,1,3,NA,NA |
| Mass (in Da) | NA,NA,NA,NA,1886.885349,NA |
| fdr | NA,NA,NA,NA,NA,NA |
| Profiling Technique | LC-MS,LC-MS,LC-MS,LC-MS,LC-MS,MALDI-TOF |
| Peptide Identification technique | MALDI-TOF/TOF,LC-MS-MS/MS,LC-MS-MS/MS,LC/MS/MS,LC-MS/MS,nano-LC/ESIeMS/MS |
| Quantification Technique | LC-MRM (multiple reaction monitoring),LC-ESI-MS,LC-ESI-MS,Multiple Reaction Monitoring,NA,NA |
| Labelled/Label Free | Labelled,Label Free,Label Free,Label Free,Label Free,Label Free |
| FDR | less than 7%,NA,NA,1.49,FDR 1 %,NA |
| CancerPDF_ID | CancerPDF_ID667, CancerPDF_ID1315, CancerPDF_ID2359, CancerPDF_ID9745, CancerPDF_ID11598, CancerPDF_ID12756, |
| p-Value | NA,NA,NA,NA,NA,NA |
| Software | FlexAnalysis 3.0 and Biotools 3.0 software,MASCOT(v. 2.2.01),MASCOT(v. 2.2.01),MASCOT,SEQUEST and Maxquant,BioworksBrowser |
| Length | 17,17,17,17,17,17 |
| Cancer Type | Ductal adenocarcinoma of the pancreas (DAP),Colorectal cancer,Normal,Lung adenocarcinoma,Melanoma,Cervical cancer |
| Database | NCBI refseq Protein Database,SwissProt Database,SwissProt Database,Swissprot Database (57.4),SwissProt Database,IPI Human Database (3.45) |
| Modification | NA,NA,NA,NA,NA,NA |
| Number of Patients | "42 normal, 28patients",30 patients and 30 healthy controls,27 healthy individuals,62 lung adenocarcinoma and 30 healthy control,8 cancer samples and 4 healthy samples,35 SCC patients (Cervical squamous cell carcinoma) and 20 healthy controls |
| Regulation | NA,NA,NA,"Differentially expressed between earlier-stage lung cancer group (stage-I, II, and IIIa) vs normal","Present in 4 cancer samples out of 8 cancer samples. ,Present in 0 healthy samples out of 4 healthy samples.",Upregulated in Cervical squamous cell carcinoma vs healthy |
| Validation | NA,Leave One out Cross validation,Leave One out Cross validation,MRM-based validation of 19 candidates,na,NA |
| Sensitivity | NA,NA,NA,NA,NA,100 % on traning data and 80% on validation dataset |
| Specificity | NA,NA,NA,NA,NA,100% on training data and 100% on validation dataset |
| Accuracy | NA,NA,NA,NA,NA,NA |
| Peptide Atlas | PeptideAtlas |
| IEDB | |