| Primary information |
|---|
| sequence ID | Seq_3177 |
| Peptide sequence | GSESGIFTNTKESSSHHPGIAEFPSRG |
| CancerPDF_ID | CancerPDF_ID11, CancerPDF_ID571, CancerPDF_ID1028, CancerPDF_ID2410, CancerPDF_ID8543, |
| PMID | 16896061,19795908,16395409,21136997,23667664 |
| Protein Name | Fibrinogen alpha chain,Fibrinogen alpha chain,Fibrinogen alpha chain,Fibrinogen alpha,Fibrinogen alpha |
| UniprotKB Entry Name | FIBA_HUMAN,FIBA_HUMAN,FIBA_HUMAN,FIBA_HUMAN,FIBA_HUMAN |
| Fluid | Serum,Plasma,Serum,Plasma,Serum |
| M/Z | 2816.25,"939.44, 704.83",2816.25,2815.3162,2815.32 |
| Charge | 1,"3, 4",1,1,1 |
| Mass (in Da) | 2816.31,NA,NA,NA,2817.99 |
| fdr | NA,NA,NA,NA,NA |
| Profiling Technique | MALDI-TOF,LC-MS,MALDI-TOF,LC-MS,MALDI-TOF |
| Peptide Identification technique | Q/TOF MS/MS,MALDI-TOF/TOF,Q/TOF/TOF and LC-MS/MS,LC-MS-MS/MS,FT-ICR MS/MS + nano-HPLC |
| Quantification Technique | NA,LC-MRM (multiple reaction monitoring),NA,LC-ESI-MS,NA |
| Labelled/Label Free | Label Free,Labelled,Label Free,Label Free,Label Free |
| FDR | NA,less than 7%,less than 1 “5,NA,NA |
| CancerPDF_ID | CancerPDF_ID11, CancerPDF_ID571, CancerPDF_ID1028, CancerPDF_ID2410, CancerPDF_ID8543, |
| p-Value | 1.00E-05,NA,2.18E-15,NA,NA |
| Software | MASCOT,FlexAnalysis 3.0 and Biotools 3.0 software,MASCOT (v 2.0.04 for Windows),MASCOT(v. 2.2.01),MASCOT |
| Length | 27,27,27,27,27 |
| Cancer Type | Metastatic thyroid carcinomas,Ductal adenocarcinoma of the pancreas (DAP),"Advanced Prostate, Breast and Bladder cancer",Normal,"Breast cancer, Lung cancer, Rectal cancer" |
| Database | NCBI refseq Protein Database,NCBI refseq Protein Database,NCBI refseq Protein Database,SwissProt Database,NA |
| Modification | NA,NA,NA,NA,NA |
| Number of Patients | 40 metastatic thyroid carcinoma patients and 40 normal for training phase and 10 metastatic thyroid carcinoma and 10 normal individuals for independent validation,"42 normal, 28patients","Advanced prostate (n = 32), breast (n = 21), and bladder (n = 20) cancer, 33 healthy",27 healthy individuals,"Breast Cancer =84, lung cancer= 70, Rectal cancer = 30patients; 500 healthy" |
| Regulation | NA,NA,"Upregulated in cancer vs normal with Ratio of median intensity (patients/Controls) = 68, 223 and 1 in prostate, bladder and breast cancer respectively",NA,NA |
| Validation | Independent validation,NA,Independent validation,Leave One out Cross validation,NA |
| Sensitivity | 95% on independent dataset,NA,97.5% on independent validation dataset,NA,NA |
| Specificity | 95% on independent dataset,NA,NA,NA,NA |
| Accuracy | NA,NA,97.5 % on validation dataset,NA,NA |
| Peptide Atlas | PeptideAtlas |
| IEDB | |