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Details of CancerPDF entry with Sequence GPPGADGQPGAKGEPGDAGAKGDAGPPGPAGP
Primary information
sequence IDSeq_2982
Peptide sequenceGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGP
CancerPDF_ID CancerPDF_ID10980,
PMID21805675
Protein NameCollagen alpha-1(I) chain
UniprotKB Entry NameCO1A1_HUMAN
FluidUrine
M/Z2771.2373
Profiling TechniqueMALDI-TOF
Peptide Identification techniqueMALDI-TOF-MS
Labelled/Label FreeLabel Free
FDR1
CancerPDF_ID CancerPDF_ID10980,
p-ValueNA
SoftwareNA
Length32
Cancer TypeMuscle-invasive bladder cancer
DatabaseSwissProt Database
Modification"Oxidation: 3, 9, 15, 26"
Number of Patients751 bladder cancer and 127 control
RegulationDifferentially expressed between cancer vs normal samples
ValidationMann-Whitney tests and areas under receiver-operator characteristic
SensitivityNA
SpecificityNA
AccuracyNA
Peptide AtlasNA
IEDBNA
Primary information
sequence IDSeq_3073
Peptide sequenceGPpGADGQpGAKGEpGDAGAKGDAGpPGPAGP
CancerPDF_ID CancerPDF_ID3773,
PMID27026199
Protein NameCollagen alpha-1(I) chain
UniprotKB Entry NameCO1A1_HUMAN
FluidUrine
fdr2770.24
Profiling Technique"CE-MS, Micro-TOF-MS"
Peptide Identification techniqueMS-MS
Labelled/Label FreeLabel Free
CancerPDF_ID CancerPDF_ID3773,
p-Valueless than 0.05
SoftwareProteome Discoverer 1.2
Length32
Cancer TypeBladder cancer
DatabaseUniprot Human non-redundant Database
Modificationp:Hydroxy-Proline
Number of Patients 425 for training(109 patients with Recurrent UBC cases and 316 negative for recurrence controls) and 211 for validation (55 UBC recurrent cases and 156 recurrent controls)
RegulationDifferentially expressed between recurrence of UBC vs recurrence control
ValidationIndependent Validation
SensitivityFor testing dataset 88%
SpecificityFor testing dataset 51%
AccuracyNA
Peptide AtlasNA
IEDBNA