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Details of CancerPDF entry with Sequence GEPGSPGENGAPGQMGPRG
Primary information
sequence IDSeq_2617
Peptide sequenceGEPGSPGENGAPGQMGPRG
CancerPDF_ID CancerPDF_ID10827,
PMID21805675
Protein NameCollagen alpha-1(I) chain
UniprotKB Entry NameCO1A1_HUMAN
FluidUrine
M/Z1799.7353
Profiling TechniqueMALDI-TOF
Peptide Identification techniqueMALDI-TOF-MS
Labelled/Label FreeLabel Free
FDR1
CancerPDF_ID CancerPDF_ID10827,
p-ValueNA
SoftwareNA
Length19
Cancer TypeMuscle-invasive bladder cancer
DatabaseSwissProt Database
Modification"Oxidation: 3, 6, 12"
Number of Patients751 bladder cancer and 127 control
RegulationDifferentially expressed between cancer vs normal samples
ValidationMann-Whitney tests and areas under receiver-operator characteristic
SensitivityNA
SpecificityNA
AccuracyNA
Peptide AtlasNA
IEDBNA
Primary information
sequence IDSeq_2640
Peptide sequenceGEpGSpGENGAPGQmGpRG
CancerPDF_ID CancerPDF_ID3468, CancerPDF_ID3656,
PMID27026199,27026199
Protein NameCollagen alpha-1(I) chain,Collagen alpha-1(I) chain
UniprotKB Entry NameCOL1A1_HUMAN,CO1A1_HUMAN
FluidUrine,Urine
M/ZNA,NA
ChargeNA,NA
Mass (in Da)NA,NA
fdr1814.77,1814.74
Profiling Technique"CE-MS, Micro-TOF-MS","CE-MS, Micro-TOF-MS"
Peptide Identification techniqueMS-MS,MS-MS
Quantification TechniqueNA,NA
Labelled/Label FreeLabel Free,Label Free
FDRNA,NA
CancerPDF_ID CancerPDF_ID3468, CancerPDF_ID3656,
p-Valueless than 0.05,5.50E-04
SoftwareProteome Discoverer 1.2,Proteome Discoverer 1.2
Length19,19
Cancer TypeBladder cancer,Bladder cancer
DatabaseUniprot Human non-redundant Database,Uniprot Human non-redundant Database
Modificationp:Hydroxy-Proline; m:Oxidized-Methionine,p:Hydroxy-Proline; m: Oxidized-Methionine
Number of Patients451 for training (341 patients and 110 normal) and 270 for testing(168 primary UBC patients and 102 normal controls);, 425 for training(109 patients with Recurrent UBC cases and 316 negative for recurrence controls) and 211 for validation (55 UBC recurrent cases and 156 recurrent controls)
RegulationDifferentially expressed between primary UBC and normal individual,Differentially expressed between recurrence of UBC vs recurrence control
ValidationIndependent Validation,Independent Validation
SensitivityFor testing dataset 91%,For testing dataset 88%
SpecificityFor testing dataset 68%,For testing dataset 51%
AccuracyFor testing dataset 76%,NA
Peptide AtlasNA
IEDB
Primary information
sequence IDSeq_2641
Peptide sequenceGEpGSpGENGApGQMGPRG
CancerPDF_ID CancerPDF_ID3650, CancerPDF_ID3652,
PMID27026199,27026199
Protein NameCollagen alpha-1(I) chain,Collagen alpha-1(I) chain
UniprotKB Entry NameCO1A1_HUMAN,CO1A1_HUMAN
FluidUrine,Urine
M/ZNA,NA
ChargeNA,NA
Mass (in Da)NA,NA
fdr1798.76,1798.75
Profiling Technique"CE-MS, Micro-TOF-MS","CE-MS, Micro-TOF-MS"
Peptide Identification techniqueMS-MS,MS-MS
Quantification TechniqueNA,NA
Labelled/Label FreeLabel Free,Label Free
FDRNA,NA
CancerPDF_ID CancerPDF_ID3650, CancerPDF_ID3652,
p-Valueless than 0.01,less than 0.01
SoftwareProteome Discoverer 1.2,Proteome Discoverer 1.2
Length19,19
Cancer TypeBladder cancer,Bladder cancer
DatabaseUniprot Human non-redundant Database,Uniprot Human non-redundant Database
Modificationp:Hydroxy-Proline,p:Hydroxy-Proline
Number of Patients 425 for training(109 patients with Recurrent UBC cases and 316 negative for recurrence controls) and 211 for validation (55 UBC recurrent cases and 156 recurrent controls), 425 for training(109 patients with Recurrent UBC cases and 316 negative for recurrence controls) and 211 for validation (55 UBC recurrent cases and 156 recurrent controls)
RegulationDifferentially expressed between recurrence of UBC vs recurrence control,Differentially expressed between recurrence of UBC vs recurrence control
ValidationIndependent Validation,Independent Validation
SensitivityFor testing dataset 88%,For testing dataset 88%
SpecificityFor testing dataset 51%,For testing dataset 51%
AccuracyNA,NA
Peptide AtlasNA
IEDB