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Details of CancerPDF entry with Sequence GEGDFLAEGGGV
Primary information
sequence IDSeq_2600
Peptide sequenceGEGDFLAEGGGV
CancerPDF_ID CancerPDF_ID1213, CancerPDF_ID9659, CancerPDF_ID11464,
PMID21136997,21533267,26992070
Protein NameFibrinogen alpha,Fibrinogen alpha chain,Fibrinogen alpha chain
UniprotKB Entry NameFIBA_HUMAN,FIBA_HUMAN,FIBA_HUMAN
FluidSerum,Serum,Serum
M/Z1106.48802,554.24,1106.488
Charge1,2,NA
Mass (in Da)NA,NA,1107.496385
fdrNA,NA,NA
Profiling TechniqueLC-MS,LC-MS,LC-MS
Peptide Identification techniqueLC-MS-MS/MS,LC/MS/MS,LC-MS/MS
Quantification TechniqueLC-ESI-MS,Multiple Reaction Monitoring,NA
Labelled/Label FreeLabel Free,Label Free,Label Free
FDR0.001,1.49,FDR 1 %
CancerPDF_ID CancerPDF_ID1213, CancerPDF_ID9659, CancerPDF_ID11464,
p-Value3.87E-05,5.37E-22,NA
SoftwareMASCOT(v. 2.2.01),MASCOT,SEQUEST and Maxquant
Length12,12,12
Cancer TypeColorectal cancer,Lung adenocarcinoma,Melanoma
DatabaseSwissProt Database,Swissprot Database (57.4),SwissProt Database
ModificationNA,NA,NA
Number of Patients30 patients and 30 healthy controls,62 lung adenocarcinoma and 30 healthy control,8 cancer samples and 4 healthy samples
RegulationDifferentially expressed between cancer vs normal,Differentially expressed between Lung cancer vs control,"Present in 3 cancer samples out of 8 cancer samples. ,Present in 0 healthy samples out of 4 healthy samples."
ValidationLeave One out Cross validation,MRM-based validation of 19 candidates,na
Sensitivity0.898,NA,NA
Specificity0.946,NA,NA
Accuracy0.917,0.656,NA
Peptide AtlasNA
IEDB437539 462581