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Details of CancerPDF entry with Sequence DEAGSEADHEGTHSTK
Primary information
sequence IDSeq_1200
Peptide sequenceDEAGSEADHEGTHSTK
CancerPDF_ID CancerPDF_ID1242, CancerPDF_ID3622, CancerPDF_ID9680,
PMID21136997,27026199,21533267
Protein NameFibrinogen alpha,Fibrinogen alpha chain,Fibrinogen alpha chain
UniprotKB Entry NameFIBA_HUMAN,FIBA_HUMAN,FIBA_HUMAN
FluidSerum,Urine,Serum
M/Z1669.68159,NA,557.57
Charge1,NA,3
Mass (in Da)NA,NA,NA
fdrNA,1669.68,NA
Profiling TechniqueLC-MS,"CE-MS, Micro-TOF-MS",LC-MS
Peptide Identification techniqueLC-MS-MS/MS,MS-MS,LC/MS/MS
Quantification TechniqueLC-ESI-MS,NA,Multiple Reaction Monitoring
Labelled/Label FreeLabel Free,Label Free,Label Free
FDRNA,NA,1.49
CancerPDF_ID CancerPDF_ID1242, CancerPDF_ID3622, CancerPDF_ID9680,
p-ValueNA,less than 0.05,NA
SoftwareMASCOT(v. 2.2.01),Proteome Discoverer 1.2,MASCOT
Length16,16,16
Cancer TypeColorectal cancer,Bladder cancer,Lung adenocarcinoma
DatabaseSwissProt Database,Uniprot Human non-redundant Database,Swissprot Database (57.4)
ModificationNA,NA,NA
Number of Patients30 patients and 30 healthy controls, 425 for training(109 patients with Recurrent UBC cases and 316 negative for recurrence controls) and 211 for validation (55 UBC recurrent cases and 156 recurrent controls),62 lung adenocarcinoma and 30 healthy control
RegulationNA,Differentially expressed between recurrence of UBC vs recurrence control,"Differentially expressed between earlier-stage lung cancer group (stage-I, II, and IIIa) vs normal"
ValidationLeave One out Cross validation,Independent Validation,MRM-based validation of 19 candidates
SensitivityNA,For testing dataset 88%,NA
SpecificityNA,For testing dataset 51%,NA
AccuracyNA,NA,NA
Peptide AtlasPeptideAtlas
IEDB