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Details of CancerPDF entry with Sequence ApGDRGEpGPPGp
Primary information
sequence IDSeq_642
Peptide sequenceAPGDRGEPGPPGP
CancerPDF_ID CancerPDF_ID10780,
PMID21805675
Protein NameCollagen alpha-1(I) chain
UniprotKB Entry NameCO1A1_HUMAN
FluidUrine
M/Z1251.5419
Profiling TechniqueMALDI-TOF
Peptide Identification techniqueMALDI-TOF-MS
Labelled/Label FreeLabel Free
FDR1
CancerPDF_ID CancerPDF_ID10780,
p-ValueNA
SoftwareNA
Length13
Cancer TypeMuscle-invasive bladder cancer
DatabaseSwissProt Database
Modification"Oxidation: 2, 8, 11"
Number of Patients751 bladder cancer and 127 control
RegulationDifferentially expressed between cancer vs normal samples
ValidationMann-Whitney tests and areas under receiver-operator characteristic
SensitivityNA
SpecificityNA
AccuracyNA
Peptide AtlasNA
IEDBNA
Primary information
sequence IDSeq_1007
Peptide sequenceApGDRGEpGPPGp
CancerPDF_ID CancerPDF_ID3552,
PMID27026199
Protein Name"Collagen alpha-1(I) chain, Collagen alpha- 1(I) chain (Alpha-1 type I collagen)"
UniprotKB Entry NameCO1A1_HUMAN
FluidUrine
fdr1250.55
Profiling Technique"CE-MS, Micro-TOF-MS"
Peptide Identification techniqueMS-MS
Labelled/Label FreeLabel Free
CancerPDF_ID CancerPDF_ID3552,
p-Valueless than 0.05
SoftwareProteome Discoverer 1.2
Length13
Cancer TypeBladder cancer
DatabaseUniprot Human non-redundant Database
Modificationp:Hydroxy-Proline
Number of Patients 425 for training(109 patients with Recurrent UBC cases and 316 negative for recurrence controls) and 211 for validation (55 UBC recurrent cases and 156 recurrent controls)
RegulationDifferentially expressed between recurrence of UBC vs recurrence control
ValidationIndependent Validation
SensitivityFor testing dataset 88%
SpecificityFor testing dataset 51%
AccuracyNA
Peptide AtlasNA
IEDBNA