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Details of CancerPDF entry with Sequence ANGAPGNDGAKGDAGAPGAPGSQGAPG
Primary information
sequence IDSeq_613
Peptide sequenceANGAPGNDGAKGDAGAPGAPGSQGAPG
CancerPDF_ID CancerPDF_ID4291, CancerPDF_ID10907,
PMID24982608,21805675
Protein NameCollagen alpha-1(I) chain,Collagen alpha-1(I) chain
UniprotKB Entry NameCO1A1_HUMAN,CO1A1_HUMAN
FluidUrine,Urine
M/ZNA,2282.9953
ChargeNA,NA
Mass (in Da)NA,NA
fdrNA,NA
Profiling TechniqueNano-LC-MS,MALDI-TOF
Peptide Identification techniqueMS/MS,MALDI-TOF-MS
Quantification TechniqueNA,NA
Labelled/Label FreeLabel Free,Label Free
FDR0.01,1
CancerPDF_ID CancerPDF_ID4291, CancerPDF_ID10907,
p-ValueNA,NA
Software"GPM search engine, MASCOT",NA
Length27,27
Cancer TypeOvarian cancer,Muscle-invasive bladder cancer
DatabaseIPI 3.71 Human Database ,SwissProt Database
ModificationNA,"Oxidation: 5, 17, 20, 26"
Number of Patients6 Ovarian cancer patients and 6 normal individuals,751 bladder cancer and 127 control
RegulationUniquely present in case of urine of ovarian cancer patients,Differentially expressed between cancer vs normal samples
ValidationNA,Mann-Whitney tests and areas under receiver-operator characteristic
SensitivityNA,NA
SpecificityNA,NA
AccuracyNA,NA
Peptide AtlasNA
IEDB
Primary information
sequence IDSeq_614
Peptide sequenceANGApGNDGAKGDAGApGApGSQGAPG
CancerPDF_ID CancerPDF_ID3725,
PMID27026199
Protein NameCollagen alpha-1(I) chain
UniprotKB Entry NameCO1A1_HUMAN
FluidUrine
fdr2265.98
Profiling Technique"CE-MS, Micro-TOF-MS"
Peptide Identification techniqueMS-MS
Labelled/Label FreeLabel Free
CancerPDF_ID CancerPDF_ID3725,
p-Valueless than 0.01
SoftwareProteome Discoverer 1.2
Length27
Cancer TypeBladder cancer
DatabaseUniprot Human non-redundant Database
Modificationp:Hydroxy-Proline
Number of Patients 425 for training(109 patients with Recurrent UBC cases and 316 negative for recurrence controls) and 211 for validation (55 UBC recurrent cases and 156 recurrent controls)
RegulationDifferentially expressed between recurrence of UBC vs recurrence control
ValidationIndependent Validation
SensitivityFor testing dataset 88%
SpecificityFor testing dataset 51%
AccuracyNA
Peptide AtlasNA
IEDBNA