ID | 1171 |
Name of the vaccine | Flagellin/F1/V |
Microbe | Bacteria |
Disease name | Plague |
Name of bacteria | Yersinia pestis |
Type of vaccine | Subunit |
Nucleic acid content | Circular DNA |
Age | 18 to 45 years |
Description of the vaccine | Plague vaccine, Flagellin/F1/V, phosphate-buffered saline, pH 6.2. |
Name of the manufacturer | National Institute of Allergy and Infectious Diseases (NIAID) |
Name of the manufacturing country | United States |
Year of manufacture | 2014 |
Clinical Phase status | Clinical - Phase 1 |
Bacterial strain | Gram-negative bacteria. |
Efficacy | NA |
Vaccine formulation | Clear, colourless solution |
Dosage | Administered on days 0 and 28 at a dose of 1, 3, 6, or 10 micrograms (mcg). |
Mechanism of action | Macrophage-protective antibody and significant CD4+ T-cell responses. |
Route of administration | NA |
Indications | NA |
Export | NA |
Approval | NA |
Adjuvant | Flagellin |
Repurposing | NA |
Side effects of vaccine | NA |
Post vaccination | NA |
Dose type | Combination doses |
Interspecies transfer | Yes (enzootic from wild rodents and their fleas) |
PubMed identifier | NA |
Clinical trial number | NCT01381744 |
Reference | https://www.nature.com/articles/s41541-020-0156-y |
Other name | NA |
Additional Links | NA
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