ID | 1033 |
Name of the vaccine | Adacel Polio |
Microbe | Bacteria |
Disease name | Diphtheria |
Name of bacteria | Corynebacterium diphtheriae |
Type of vaccine | Combination |
Nucleic acid content | DNA |
Age | 4 years and older |
Description of the vaccine | Tetanus toxoid, reduced diphtheria toxoid and acellular pertussis vaccine adsorbed combined with inactivated poliomyelitis vaccine. |
Name of the manufacturer | Sanofi Pasteur Limited |
Name of the manufacturing country | Canada |
Year of manufacture | 2013 |
Clinical Phase status | Approved |
Bacterial strain | Gram-positive bacillus. |
Efficacy | 83.8% of adults, 97.1% of adolescents and at least 97.6% of children achieved a seroprotective antitoxin level of 0.1 IU/mL. |
Vaccine formulation | Suspension for injection |
Dosage | Single dose of 0.5 mL. |
Mechanism of action | Serum diphtheria antitoxin level:
0.01 IU/mL : Lowest protection
at least 0.1 IU/mL : Protective |
Route of administration | Intramuscular |
Indications | Immunization against tetanus, diphtheria, pertussis and poliomyelitis. |
Export | NA |
Approval | NA |
Adjuvant | Aluminium phosphate |
Repurposing | For tetanus, pertussis and poliomyelitis. |
Side effects of vaccine | Redness, swelling, pain, tired, headache, generalized body ache and sore or swollen joints. |
Post vaccination | NA |
Dose type | Single dose |
Interspecies transfer | NA |
PubMed identifier | NA |
Clinical trial number | NA |
Reference | https://pdf.hres.ca/dpd_pm/00021710.PDF |
Other name | NA |
Additional Links | https://www.toronto.ca/community-people/health-wellness-care/diseases-medications-vaccines/diphtheria-tetanus-pertussis-and-polio-vaccines/
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