Browse result page of B3Pdb

The total number entries retrieved from this search are 92, scroll left/right for detailed information.
B3pdbIDPEPTIDE NAMEPEPTIDE SEQUENCE (1-letter)PEPTIDE SEQUENCE (3-letter)N-TERMINAL MODIFICATIONC-TERMINAL MODIFICATION CHEMICAL MODIFICATIONPEPTIDE LENGTHPEPTIDE CONFORMATIONPEPTIDE NATURESOURCE/ORIGIN OF PEPTIDESMILESCELL LINEIn vitro CONCENTRATIONIn vitro METHODIn vitro RESULTANIMAL MODELIn vivo CONCENTRATIONIn vivo MODE OF DELIVERYIn vivo METHODIn vivo RESULTACTIONTRANSPORT TYPESUBCELLULAR LOCALISATIONCOMBINATIONPHYSICAL CONDITIONRESPONSERESULTLABELPMID
b3pdb_0001MtfpepDSSHAFTLDELRAspSerSerHisAlaPheThrLeuAspGluLeuArgNAPolyethylene glycol (PEG)4 linkerNA12LinearNAMelanotransferrinN[C@@]([H])(CC(=O)O)C(=O)N[C@@]([H])(CO)C(=O)N[C@@]([H])(CO)C(=O)N[C@@]([H])(CC1=CN=C-N1)C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(Cc1ccccc1)C(=O)N[C@@]([H])([C@]([H])(O)C)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(CC(=O)O)C(=O)N[C@@]([H])(CCC(=O)O)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(CCCNC(=N)N)C(=O)ONANANANAMice2 MTfpep per NIP228 antibodyIntravenous 3D confocal fluorescence microscopyTwo times greater fractional fluorescence was measured in the brain parenchyma. It delivers a protein-based interleukin 1 receptor antagonist across the BBB and ameliorates Transcytosis Surface of normal brain endothelial cells, the main constituent of the BBB, and is able to cross thr Successfully delivers therapeutic amounts of an an Neuropathic pain Stability/half life 5.5 days NA 29845881
b3pdb_0005R-RfaSLKPAANLPLRFSerLeuLysProAlaAlaAsnLeuProLeuArgPheNANA5(6)-carboxyfluorescein attched to peptide12LinearNADodeca-neuropeptide (SLKPAANLPLRF) of frog brain.N[C@@]([H])(CO)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(CCCCN)C(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(CC(=O)N)C(=O)N[C@@]([H])(CC(C)C)C(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(CCCNC(=N)N)C(=O)N[C@@]([H])(Cc1ccccc1)C(=O)ONANANANARat primary cortical neuronsNAIntraperitonealFourier Transform Infrared SpectroscopyInhibition of Aβ fibrillation It inhibits Aβ fibrillization, moderately binds with tubulin and promotes tubulin polymerization as NA NA NA Alzheimer’s disease NA NA NA 30408415
b3pdb_0038ApoB11RLTRKRGLKLAArgLeuThrArgLysArgGlyLeuLysLeuAlaNA5 Gly (G) and 9 Arg (R) amino acids to the C-termiCoupled with a 9-amiNA acid arginine linker11NANAApoB38 peptideN[C@@]([H])(CCCNC(=N)N)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])([C@]([H])(O)C)C(=O)N[C@@]([H])(CCCNC(=N)N)C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])(CCCNC(=N)N)C(=O)NCC(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(C)C(=O)OMouse cholinergic cell line Neuro2A (N2A)100000 cells/wellLaser scanning confocal microscopyIt crosses the BBB with conguagted siRNA for alpha-syn.Transgenic Mice50 microgramIntraperitonealLaser scanning confocal microscopyIt can transport siα-syn across the BBB as a therapeutic option for synucleinopathies. It showed reduced accumulation of α-syn associated with amelioration of the neurodegenerative and i NA Neurons and glial cellsexhibiting α-syn accumulation Combined with siRNA for alpha-syn Lewy body disease NA NA NA 30849508
b3pdb_0039C2-9rCDIFTNSRGKRACysAspIlePheThrAsnSerArgGlyLysArgAlaNA4 Gly (G) and nine d-Arg (9r) residues to the CterCoupled with a 9-amiNA acid arginine linker12NANArhabdovirus glycoproteinN[C@@]([H])(CS)C(=O)N[C@@]([H])(CC(=O)O)C(=O)N[C@@]([H])([C@]([H])(CC)C)C(=O)N[C@@]([H])(Cc1ccccc1)C(=O)N[C@@]([H])([C@]([H])(O)C)C(=O)N[C@@]([H])(CC(=O)N)C(=O)N[C@@]([H])(CO)C(=O)N[C@@]([H])(CCCNC(=N)N)C(=O)NCC(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])(CCCNC(=N)N)C(=O)N[C@@]([H])(C)C(=O)OMouse cholinergic cell line Neuro2A (N2A)100000 cells/wellLaser scanning confocal microscopyIt crosses the BBB with conguagted siRNA for alpha-syn.Transgenic Mice50 microgramIntraperitonealLaser scanning confocal microscopyIt can transport siα-syn across the BBB as a therapeutic option for synucleinopathies. It showed reduced accumulation of α-syn associated with amelioration of the neurodegenerative and i NA Neurons and glial cellsexhibiting α-syn accumulation Combined with siRNA for alpha-syn Lewy body disease NA NA NA 30849508
b3pdb_0052Phage clone 1.2VAARTGEIYVPWValAlaAlaArgThrGlyGluIleTyrValProTrpNANANA12LinearCationicChemically synthesizedN[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(CCCNC(=N)N)C(=O)N[C@@]([H])([C@]([H])(O)C)C(=O)NCC(=O)N[C@@]([H])(CCC(=O)O)C(=O)N[C@@]([H])([C@]([H])(CC)C)C(=O)N[C@@]([H])(Cc1ccc(O)cc1)C(=O)N[C@@]([H])(C(C)C)C(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(CC(=CN2)C1=C2C=CC=C1)C(=O)OSH-SY5Y cellsNAUHPLC-MS/MSThe phage display adverses the BBB with the peptide.NANANANANA Peptides bound specifically to primary endothelial cells and could traverse the BBB. Transcytosis NA Combined with phage display NA Stability/half life 1.5 x 10e-6 cm/s NA 32079185
b3pdb_0053Phage clone 1.3GLHTSATNLYLHGlyLeuHisThrSerAlaThrAsnLeuTyrLeuHisNANANA12LinearCationicChemically synthesizedNCC(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(CC1=CN=C-N1)C(=O)N[C@@]([H])([C@]([H])(O)C)C(=O)N[C@@]([H])(CO)C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])([C@]([H])(O)C)C(=O)N[C@@]([H])(CC(=O)N)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(Cc1ccc(O)cc1)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(CC1=CN=C-N1)C(=O)OSH-SY5Y cellsNAUHPLC-MS/MSThe phage display adverses the BBB with the peptide.NANANANANA Peptides bound specifically to primary endothelial cells and could traverse the BBB. Transcytosis NA Combined with phage display NA Stability/half life 3.3 x 10e-7 cm/s NA 32079185
b3pdb_0054Tfr1THRPPMWSPVWPThrHisArgProProMetTrpSerProValTrpProFAM is conjgated at the N-terminalNANA12LinearNAChemically synthesizedN[C@@]([H])([C@]([H])(O)C)C(=O)N[C@@]([H])(CC1=CN=C-N1)C(=O)N[C@@]([H])(CCCNC(=N)N)C(=O)N1[C@@]([H])(CCC1)C(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(CCSC)C(=O)N[C@@]([H])(CC(=CN2)C1=C2C=CC=C1)C(=O)N[C@@]([H])(CO)C(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(CC(=CN2)C1=C2C=CC=C1)C(=O)N1[C@@]([H])(CCC1)C(=O)ObEnd.3 cellsNAImmunofluorescence microscopyIt shows the permeability towards the BBB.NANANANANA These novel peptide conjugates have the capacity to act as promising brain shuttles Receptor-mediated transcytosis NA Combined NA NA NA NA 32055384
b3pdb_0072NeurotensinELYENKPRRPYILpGlu-Leu-Tyr-Glu-Asn-Lys-Pro-Arg-Arg-Pro-Tyr-Ile-Leu-OHNANANA13TridecapeptideNAbovine hypothalamusN[C@@]([H])(CCC(=O)O)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(Cc1ccc(O)cc1)C(=O)N[C@@]([H])(CCC(=O)O)C(=O)N[C@@]([H])(CC(=O)N)C(=O)N[C@@]([H])(CCCCN)C(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(CCCNC(=N)N)C(=O)N[C@@]([H])(CCCNC(=N)N)C(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(Cc1ccc(O)cc1)C(=O)N[C@@]([H])([C@]([H])(CC)C)C(=O)N[C@@]([H])(CC(C)C)C(=O)ONANANANAAdult male Swiss-Webster miceNANAStudent's t-test (two-tailed) and Mann-Whitney U-testNA Not able to cross the BBB in sufficient quantities to exert direct brain effects. Can modify the sed NA NA NA NA NA NA NA 406965
b3pdb_0135G23HLNILSTLWKYRHisLeuAsnIleLeuSerThrLeuTrpLysTyrArgNANANA12LinearNAPhage display of prion proteinsNAhCMEC/D3NAFluoroscent measureG23 peptide can cross basal layerNANANANANA NA Transcytosis as well as BBB penetration NA NA NA NA NA NA 22536790
b3pdb_0136G23HLNILSTLWKYRHisLeuAsnIleLeuSerThrLeuTrpLysTyrArgNANANA12LinearNAPhage display of prion proteinsNANANANANABALB/c miceNAIntravenous Radioimaging0.052 + 0.019 of fluoroscent measured in btain tissue after 4 hours NA Transcytosis as well as BBB penetration NA NA NA NA NA NA 22536790
b3pdb_0137G23HLNILSTLWKYRHisLeuAsnIleLeuSerThrLeuTrpLysTyrArgNANANA12LinearNAPhage display of prion proteinsNANANANANABALB/c miceNAIntravenous Radioimaging0.047 + 0.031 of fluoroscent measured in btain tissue after 24 hours NA Transcytosis as well as BBB penetration NA NA NA NA NA NA 22536790
b3pdb_0138Scr-G23KISHLLNYRTWLLysIleSerHisLeuLeuAsnTyrArgThrTrpLeuNANANA12LinearNAPhage display of prion proteinsNANANANANABALB/c miceNAIntravenous Radioimaging0.013 + 0.006 of fluoroscent measured in btain tissue after 4 hours NA Transcytosis as well as BBB penetration NA NA NA NA NA NA 22536790
b3pdb_0139Scr-G23KISHLLNYRTWLLysIleSerHisLeuLeuAsnTyrArgThrTrpLeuNANANA12LinearNAPhage display of prion proteinsNANANANANABALB/c miceNAIntravenous Radioimaging0.008 + 0.002 of fluoroscent measured in btain tissue after 24 hours NA Transcytosis as well as BBB penetration NA NA NA NA NA NA 22536790
b3pdb_0147Goldnanoparticle conTHRPPMWSPVWPThrHisArgProProMetTrpSerProValTrpProNANAConjugated with CLPFFD goldnaNAparticle12LinearCationicChemically synthesizedNANANANANAAdult Sprague-Dawley rats1.86 mg/KgIntraperitonealInstrumental neutron activation analysis and Nissl stainingConjugate was found to cross blodd brain barrier; does not effect mice survival; no toxicity as meas NA NA NA NA Alzheimer NA NA NA 22795856
b3pdb_0160ASA-TatYGRKKRRQRRRTyrGlyArgLysLysArgArgGlnArgArgArgConjugated with ASA drugNANA11LinearNANANACHO cell line2.5 microgram/ mlcellular uptake assay 12.6 % cellular uptakeNANANANANA NA Transendocytosis NA NA Lysosomal disorder NA NA NA 24573272
b3pdb_0165ASA-TatYGRKKRRQRRRTyrGlyArgLysLysArgArgGlnArgArgArgConjugated with ASA drugNANA11LinearNANANAbEND cell line2.5 microgram/ mlcellular uptake assay 16.6 % cellular uptakeNANANANANA NA Transendocytosis NA NA Lysosomal disorder NA NA NA 24573272
b3pdb_0170ASA-TatYGRKKRRQRRRTyrGlyArgLysLysArgArgGlnArgArgArgConjugated with ASA drugNANA11LinearNANANAPBCECs cell line0.02% cells were addedBasolateral screening assay100% transferNANANANANA NA Basolateral NA NA Lysosomal disorder NA NA NA 24573272
b3pdb_0177Parent peptideTHRPPMWSPVWPThrHisArgProProMetTrpSerProValTrpProNAAmidatedNA12LinearNANANARat astrocyte50 micromolarHPLC, MALDI-TOF to analyze the peptide transport and apparent permeability12.5+/- 3.4 apparent permeabilityNANANANANA NA can transport cargo NA NA NA NA NA NA 25650865
b3pdb_0178N-methylaed parent pT(Nme)H(Nme)RPPM(Nme)WSPVWPNANAAmidatedNA12LinearNANANARat astrocyte50 micromolarHPLC, MALDI-TOF to analyze the peptide transport and apparent permeability9.9+/- 1.6 apparent permeabilityNANANANANA NA can transport cargo NA NA NA NA NA NA 25650865
b3pdb_0179Enatiomeric parent pTHRPPMWSPVWPThrHisArgProProMetTrpSerProValTrpProNAAmidatedNA12LinearNANANARat astrocyte50 micromolarHPLC, MALDI-TOF to analyze the peptide transport and apparent permeability14.5+/- 2.0 apparent permeabilityNANANANANA NA can transport cargo NA NA NA NA NA NA 25650865
b3pdb_0180Retro-enantiomeric pPWVPSWMPPRHTProTrpValProSerTrpMetProProArgHisThrNAAmidatedNA12LinearNANANARat astrocyte50 micromolarHPLC, MALDI-TOF to analyze the peptide transport and apparent permeability21.5+/- 2.8 apparent permeabilityNANANANANA NA can transport cargo NA NA NA NA NA NA 25650865
b3pdb_0181Parent peptideTHRPPMWSPVWPThrHisArgProProMetTrpSerProValTrpProNAAmidatedNA12LinearNANANARat astrocyte50 micromolarHPLC, MALDI-TOF to analyze the peptide transport and apparent permeability14.9+/- 2.5 apparent permeabilityNANANANANA NA can transport cargo NA NA NA NA NA NA 25650865
b3pdb_0182N-methylaed parent pT(Nme)H(Nme)RPPM(Nme)WSPVWPNANAAmidatedNA12LinearNANANARat astrocyte50 micromolarHPLC, MALDI-TOF to analyze the peptide transport and apparent permeability11.7+/- 6.4 apparent permeabilityNANANANANA NA can transport cargo NA NA NA NA NA NA 25650865
b3pdb_0183Enatiomeric parent pTHRPPMWSPVWPThrHisArgProProMetTrpSerProValTrpProNAAmidatedNA12LinearNANANARat astrocyte50 micromolarHPLC, MALDI-TOF to analyze the peptide transport and apparent permeability17.2+/- 1.2 apparent permeabilityNANANANANA NA can transport cargo NA NA NA NA NA NA 25650865
b3pdb_0184Retro-enantiomeric pPWVPSWMPPRHTProTrpValProSerTrpMetProProArgHisThrNAAmidatedNA12LinearNANANARat astrocyte50 micromolarHPLC, MALDI-TOF to analyze the peptide transport and apparent permeability25.1+/- 3.0 apparent permeabilityNANANANANA NA can transport cargo NA NA NA NA NA NA 25650865
b3pdb_0185Parent peptideTHRPPMWSPVWPThrHisArgProProMetTrpSerProValTrpProNAAmidatedNA12LinearNANANARat astrocyte50 micromolarPAMPA method for cargo delivery and transportation efficiency16.2+/- 1.3 apparent permeabilityNANANANANA NA can transport cargo NA carboxyfluoroscein Antiallergic drug NA NA NA 25650865
b3pdb_0186N-methylaed parent pT(Nme)H(Nme)RPPM(Nme)WSPVWPNANAAmidatedNA12LinearNANANARat astrocyte50 micromolarPAMPA method for cargo delivery and transportation efficiency0.14.7+/- 0.01 apparent permeabilityNANANANANA NA can transport cargo NA H-a(Nme)f-D-2-nal-vlkk-Nh2 Antialzheimer peptide NA NA NA 25650865
b3pdb_0187Enatiomeric parent pTHRPPMWSPVWPThrHisArgProProMetTrpSerProValTrpProNAAmidatedNA12LinearNANANARat astrocyte50 micromolarPAMPA method for cargo delivery and transportation efficiency0.19.2+/- 0.07 apparent permeabilityNANANANANA NA can transport cargo NA iron oxide nanoparticle NA NA NA NA 25650865
b3pdb_0188Retro-enantiomeric pPWVPSWMPPRHTProTrpValProSerTrpMetProProArgHisThrNAAmidatedNA12LinearNANANARat astrocyte50 micromolarPAMPA method for cargo delivery and transportation efficiency0.27+/- 0.03 apparent permeabilityNANANANANA NA can transport cargo NA Quantum dots NA NA NA NA 25650865
b3pdb_0189Parent peptideTHRPPMWSPVWPThrHisArgProProMetTrpSerProValTrpProNAAmidatedNA12LinearNANANARat astrocyte50 micromolarPAMPA method for cargo delivery and transportation efficiency17.1+/- 2.6 transport efficiencyNANANANANA NA can transport cargo NA carboxyfluoroscein Antiallergic drug NA NA NA 25650865
b3pdb_0190N-methylaed parent pT(Nme)H(Nme)RPPM(Nme)WSPVWPNANAAmidatedNA12LinearNANANARat astrocyte50 micromolarPAMPA method for cargo delivery and transportation efficiency0.20+/- 0.01 transport efficiencyNANANANANA NA can transport cargo NA H-a(Nme)f-D-2-nal-vlkk-Nh2 Antialzheimer peptide NA NA NA 25650865
b3pdb_0191Enatiomeric parent pTHRPPMWSPVWPThrHisArgProProMetTrpSerProValTrpProNAAmidatedNA12LinearNANANARat astrocyte50 micromolarPAMPA method for cargo delivery and transportation efficiency0.22+/- 0.05 transport efficiencyNANANANANA NA can transport cargo NA iron oxide nanoparticle NA NA NA NA 25650865
b3pdb_0192Retro-enantiomeric pPWVPSWMPPRHTProTrpValProSerTrpMetProProArgHisThrNAAmidatedNA12LinearNANANARat astrocyte50 micromolarPAMPA method for cargo delivery and transportation efficiency0.031+/- 0.02 transport efficiencyNANANANANA NA can transport cargo NA Quantum dots NA NA NA NA 25650865
b3pdb_0197Bacteriophage deriveRRPAPLIMFRMIArgArgProAlaProLeuIleMetPheArgMetIleNANANA12LinearNAT7 Bacteiophage derivedNANANANANAMale wistar miceNANANANA Can cross BBB as well as Blood CSF barrier Transendocytosis NA NA Alzheimer NA NA NA 26411801
b3pdb_0198Bacteriophage deriveSRYSIGGNNGVTSerArgTyrSerIleGlyGlyAsnAsnGlyValThrNANANA12LinearNAT7 Bacteiophage derivedNANANANANAMale wistar miceNANANANA Can cross BBB as well as Blood CSF barrier Transendocytosis NA NA Alzheimer NA NA NA 26411801
b3pdb_0202Bacteriophage deriveRSTASTSYPFFFArgSerThrAlaSerThrSerTyrProPhePhePheNANANA12LinearNAT7 Bacteiophage derivedNANANANANAMale wistar miceNANANANA Can cross BBB as well as Blood CSF barrier Transendocytosis NA NA Alzheimer NA NA NA 26411801
b3pdb_0203Bacteriophage deriveYAWGGGWVLQWFTyrAlaTrpGlyGlyGlyTrpValLeuGlnTrpPheNANANA12LinearNAT7 Bacteiophage derivedNANANANANAMale wistar miceNANANANA Can cross BBB as well as Blood CSF barrier Transendocytosis NA NA Alzheimer NA NA NA 26411801
b3pdb_0204Bacteriophage deriveDAAESVLVGTVRAspAlaAlaGluSerValLeuValGlyThrValArgNANANA12LinearNAT7 Bacteiophage derivedNANANANANAMale wistar miceNANANANA Can cross BBB as well as Blood CSF barrier Transendocytosis NA NA Alzheimer NA NA NA 26411801
b3pdb_0205Bacteriophage deriveISNRSHKGLMVGIleSerAsnArgSerHisLysGlyLeuMetValGlyNANANA12LinearNAT7 Bacteiophage derivedNANANANANAMale wistar miceNANANANA Can cross BBB as well as Blood CSF barrier Transendocytosis NA NA Alzheimer NA NA NA 26411801
b3pdb_0206Bacteriophage deriveYNQSLLQGYRYWTyrAsnGlnSerLeuLeuGlnGlyTyrArgTyrTrpNANANA12LinearNAT7 Bacteiophage derivedNANANANANAMale wistar miceNANANANA Can cross BBB as well as Blood CSF barrier Transendocytosis NA NA Alzheimer NA NA NA 26411801
b3pdb_0208Bacteriophage deriveMRWFFSHASQGRMetArgTrpPhePheSerHisAlaSerGlnGlyArgNANANA12LinearNAT7 Bacteiophage derivedNANANANANAMale wistar miceNANANANA Can cross BBB as well as Blood CSF barrier Transendocytosis NA NA Alzheimer NA NA NA 26411801
b3pdb_0209Bacteriophage deriveRLSSVDSDLSGCArgLeuSerSerValAspSerAspLeuSerGlyCysNANANA12LinearNAT7 Bacteiophage derivedNANANANANAMale wistar miceNANANANA Can cross BBB as well as Blood CSF barrier Transendocytosis NA NA Alzheimer NA NA NA 26411801
b3pdb_0210Bacteriophage deriveGRPQKINGARVCGlyArgProGlnLysIleAsnGlyAlaArgValCysNANANA12LinearNAT7 Bacteiophage derivedNANANANANAMale wistar miceNANANANA Can cross BBB as well as Blood CSF barrier Transendocytosis NA NA Alzheimer NA NA NA 26411801
b3pdb_0212Bacteriophage deriveKVAWRVFSLFWKLysValAlaTrpArgValPheSerLeuPheTrpLysNANANA12LinearNAT7 Bacteiophage derivedNANANANANAMale wistar miceNANANANA Can cross BBB as well as Blood CSF barrier Transendocytosis NA NA Alzheimer NA NA NA 26411801
b3pdb_0213Bacteriophage deriveGFVRFRLSNTRGlyPheValArgPheArgLeuSerAsnThrArgNANANA11LinearNAT7 Bacteiophage derivedNANANANANAMale wistar miceNANANANA Can cross BBB as well as Blood CSF barrier Transendocytosis NA NA Alzheimer NA NA NA 26411801
b3pdb_0233ProtamineVSRRRRRRGGRRRRValSerArgArgArgArgArgArgGlyGlyArgArgArgArgNANANA13LinearCationicDerived from protamineNANANANANABALB/c mice10 microliter per nostrilIntranasalIn vivo imagingPeptide + BSA combination deleiveerd in brain olfactory bulb and littlebit in cerebral peptide can deliver drug into brain tissue NA NA Peptide+BSA NA NA NA NA 27471676
b3pdb_0234PepH1VQQLTKRFSLValGlnGlnLeuThrLysArgPheSerLeuNANANA14LinearCationicDerived from dengue virus capsidNAbEND cell line5 microCi/mlGamma counter radioactivity measure for TcPz73.83+/- 9.40NANANANANA Can cross blood brain barrier as well as shows membrane adsorption Transmigration Can be migrated to liver, kidney etc. NA NA NA NA NA 28263555
b3pdb_0236PepH3AGILKRWAlaGlyIleLeuLysArgTrpNANANA14LinearCationicDerived from dengue virus capsidNAbEND cell line5 microCi/mlGamma counter radioactivity measure for TcPz67.33+/- 1.20NANANANANA Can cross blood brain barrier as well as shows membrane adsorption Transmigration Can be migrated to liver, kidney etc. NA NA NA NA NA 28263555
b3pdb_0238PepH1VQQLTKRFSLValGlnGlnLeuThrLysArgPheSerLeuNANANA14LinearCationicDerived from dengue virus capsidNAbEND cell line5 microCi/mlGamma counter radioactivity measure for gaNODA71.47+/- 3.70NANANANANA Can cross blood brain barrier as well as shows membrane adsorption Transmigration Can be migrated to liver, kidney etc. NA NA NA NA NA 28263555
b3pdb_0240PepH3AGILKRWAlaGlyIleLeuLysArgTrpNANANA14LinearCationicDerived from dengue virus capsidNAbEND cell line5 microCi/mlGamma counter radioactivity measure for gaNODA72.63 +/- 0.70NANANANANA Can cross blood brain barrier as well as shows membrane adsorption Transmigration Can be migrated to liver, kidney etc. NA NA NA NA NA 28263555