Length | Dha= Didehydroalanine, Dhb= Didehydroaminobutyric acid, Abu= 2-aminobutyric acid, Lanthionine (Ala-S-Ala) formation from 3-7 Ala, and β-methyllanthionine (Abu-S-Ala) from 8-11, 13-19, 23-26, 25-28 in between Abu and Ala |
Primary information |
---|
ID | antitb_1145, |
Name | 21468208 |
N-Terminal modification | Nisin A |
C-Terminal Modification | I-(Dhb)-AI-(Dha)-LA-(Abu)-PGAK-(Abu)-GALMGANMK-(Abu)-A-(Abu)-ANASIHV-(Dha)-K |
Chemical Modification | Free |
Linear/Cyclic | Free |
Length | Dha= Didehydroalanine, Dhb= Didehydroaminobutyric acid, Abu= 2-aminobutyric acid, Lanthionine (Ala-S-Ala) formation from 3-7 Ala, and β-methyllanthionine (Abu-S-Ala) from 8-11, 13-19, 23-26, 25-28 in between Abu and Ala |
Chirality | Cyclic (5 hinge region due to presence of lanthion |
Nature | 34 |
Source | L |
Species | Natural |
Strain | Produced by Lactococcus lactis |
Inhibition Concentration | Mycobacterium tuberculosis |
In Vitro/ In vivo | Mycobacterium tuberculosis H37Ra |
Inhibition Concentration | In vitro |
Sequence | 2010 |
Cytotoxicity | None |
In vivo Model | NA |
Lethal Dose | NA |
Immune Responce | None |
Mechanism of Action | NA |
Target | NA |
Combination Therapy | NA |
Other activities | NA |
PMID | None |
Year of Publication | Antibacterial (Shigella, Pseudomonas and Salmonella, S. aureus, S. agalactiae and L. monocytogenes) |
Tertiary Structure (Technique) | Not Predicted), |
Primary information |
---|
ID | antitb_1146, |
Name | 21468208 |
N-Terminal modification | Nisin A |
C-Terminal Modification | I-(Dhb)-AI-(Dha)-LA-(Abu)-PGAK-(Abu)-GALMGANMK-(Abu)-A-(Abu)-ANASIHV-(Dha)-K |
Chemical Modification | Free |
Linear/Cyclic | Free |
Length | Dha= Didehydroalanine, Dhb= Didehydroaminobutyric acid, Abu= 2-aminobutyric acid, Lanthionine (Ala-S-Ala) formation from 3-7 Ala, and β-methyllanthionine (Abu-S-Ala) from 8-11, 13-19, 23-26, 25-28 in between Abu and Ala |
Chirality | Cyclic (5 hinge region due to presence of lanthion |
Nature | 34 |
Source | L |
Species | Natural |
Strain | Produced by Lactococcus lactis |
Inhibition Concentration | Mycobacterium kansasii |
In Vitro/ In vivo | Mycobacterium kansasii CIT11/06 |
Inhibition Concentration | In vitro |
Sequence | 2010 |
Cytotoxicity | None |
In vivo Model | NA |
Lethal Dose | NA |
Immune Responce | None |
Mechanism of Action | NA |
Target | NA |
Combination Therapy | NA |
Other activities | NA |
PMID | None |
Year of Publication | Antibacterial (Shigella, Pseudomonas and Salmonella, S. aureus, S. agalactiae and L. monocytogenes) |
Tertiary Structure (Technique) | Not Predicted), |
Primary information |
---|
ID | antitb_1147, |
Name | 21468208 |
N-Terminal modification | Nisin A |
C-Terminal Modification | I-(Dhb)-AI-(Dha)-LA-(Abu)-PGAK-(Abu)-GALMGANMK-(Abu)-A-(Abu)-ANASIHV-(Dha)-K |
Chemical Modification | Free |
Linear/Cyclic | Free |
Length | Dha= Didehydroalanine, Dhb= Didehydroaminobutyric acid, Abu= 2-aminobutyric acid, Lanthionine (Ala-S-Ala) formation from 3-7 Ala, and β-methyllanthionine (Abu-S-Ala) from 8-11, 13-19, 23-26, 25-28 in between Abu and Ala |
Chirality | Cyclic (5 hinge region due to presence of lanthion |
Nature | 34 |
Source | L |
Species | Natural |
Strain | Produced by Lactococcus lactis |
Inhibition Concentration | Mycobacterium avium |
In Vitro/ In vivo | Mycobacterium avium subsp. Hominissuis (CIT05/03) |
Inhibition Concentration | In vitro |
Sequence | 2010 |
Cytotoxicity | None |
In vivo Model | NA |
Lethal Dose | NA |
Immune Responce | None |
Mechanism of Action | NA |
Target | NA |
Combination Therapy | NA |
Other activities | NA |
PMID | None |
Year of Publication | Antibacterial (Shigella, Pseudomonas and Salmonella, S. aureus, S. agalactiae and L. monocytogenes) |
Tertiary Structure (Technique) | Not Predicted), |
Primary information |
---|
ID | antitb_1148, |
Name | 21468208 |
N-Terminal modification | Nisin A |
C-Terminal Modification | I-(Dhb)-AI-(Dha)-LA-(Abu)-PGAK-(Abu)-GALMGANMK-(Abu)-A-(Abu)-ANASIHV-(Dha)-K |
Chemical Modification | Free |
Linear/Cyclic | Free |
Length | Dha= Didehydroalanine, Dhb= Didehydroaminobutyric acid, Abu= 2-aminobutyric acid, Lanthionine (Ala-S-Ala) formation from 3-7 Ala, and β-methyllanthionine (Abu-S-Ala) from 8-11, 13-19, 23-26, 25-28 in between Abu and Ala |
Chirality | Cyclic (5 hinge region due to presence of lanthion |
Nature | 34 |
Source | L |
Species | Natural |
Strain | Produced by Lactococcus lactis |
Inhibition Concentration | Mycobacterium avium |
In Vitro/ In vivo | Mycobacterium avium paratuberculosis (ATCC 19698) |
Inhibition Concentration | In vitro |
Sequence | 2010 |
Cytotoxicity | None |
In vivo Model | NA |
Lethal Dose | NA |
Immune Responce | None |
Mechanism of Action | NA |
Target | NA |
Combination Therapy | NA |
Other activities | NA |
PMID | None |
Year of Publication | Antibacterial (Shigella, Pseudomonas and Salmonella, S. aureus, S. agalactiae and L. monocytogenes) |
Tertiary Structure (Technique) | Not Predicted), |