Welcome to Peptide Card of AntiTbPdb
| This page displays user query in tabular form. |
GKKKKSVQWCA details |
| Primary information | |
|---|---|
| ID | antitb_1170, |
| Name | 24709266 |
| N-Terminal modification | hLFcin1-11 all K |
| C-Terminal Modification | GKKKKSVQWCA |
| Chemical Modification | Free |
| Linear/Cyclic | Free |
| Length | None |
| Chirality | Linear |
| Nature | 11 |
| Source | L |
| Origin | Cationic |
| Species | Synthetic |
| Inhibition Concentration | Mycobacterium avium |
| In Vitro/ In vivo | Mycobacterium avium strain 2447 smooth transparent variant (SmT) |
| Cell Line | IC50 = 39.1 ± 6.9 |
| Inhibition Concentration | In vitro |
| Sequence | 2014 |
| Cytotoxicity | None |
| In vivo Model | NA |
| Lethal Dose | NA |
| Immune Responce | None |
| Mechanism of Action | NA |
| Target | NA |
| Combination Therapy | Permeabilization of peptide causes significant changes both in the surface and in the ultrastructural organization of the mycobacterial cells. |
| Other activities | Cell envelope |
| PMID | None |
| Year of Publication | None |
| Tertiary Structure (Technique) | Not Predicted), |
| Primary information | |
|---|---|
| ID | antitb_1899, |
| Name | 24709266 |
| N-Terminal modification | Human lactoferricin 1-11 |
| C-Terminal Modification | GKKKKSVQWCA |
| Chemical Modification | Free |
| Linear/Cyclic | Free |
| Length | None |
| Chirality | Linear |
| Nature | 11 |
| Source | L |
| Origin | Cationic |
| Species | Natural |
| Strain | Derived from human lactoferricin protein |
| Inhibition Concentration | Mycobacterium avium |
| In Vitro/ In vivo | Mycobacterium avium |
| Cell Line | Mycobacterium avium 2447 smT |
| Inhibition Concentration | In vitro |
| Sequence | 2014 |
| Cytotoxicity | NA |
| In vivo Model | Tratment with this concentration inhibit 50% bacterial growth |
| Lethal Dose | NA |
| Immune Responce | NA |
| Mechanism of Action | NA |
| Target | NA |
| Combination Therapy | NA |
| Other activities | Lipid bilayer |
| PMID | NA |
| Year of Publication | NA |
| Tertiary Structure (Technique) | Not Predicted), |