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(MDA)-P-(AHMOD)-(Aib)-(Aib)-V-V-(Aib)-(Aib)-(AMAE) details |
Primary information | |
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ID | antitb_1299, |
Name | 20483615 |
N-Terminal modification | Trichoderins B |
C-Terminal Modification | (MDA)-P-(AHMOD)-(Aib)-(Aib)-V-V-(Aib)-(Aib)-(AMAE) |
Chemical Modification | Addition of MDA = 2-methyl decanoic acid. |
Linear/Cyclic | Addition of AMAE = 2-[(20-aminopropyl) methylamino] ethanol. |
Length | AHMOD = 2-amino-6-hydroxy-4-methyl-8-oxodecanoic acid, Aib = α-amino- isobutyric acid |
Chirality | Linear |
Nature | 8 |
Source | L |
Species | Natural |
Strain | Isolated from a culture of marine sponge derived fungus of Trichoderma sp. |
Inhibition Concentration | Mycobacterium smegmatis |
In Vitro/ In vivo | Mycobacterium smegmatis |
Cell Line | MIC =0.63 μg/mL |
Inhibition Concentration | In vitro |
Sequence | 2010 |
Cytotoxicity | None |
In vivo Model | NA |
Lethal Dose | NA |
Immune Responce | None |
Mechanism of Action | NA |
Target | NA |
Combination Therapy | NA |
Other activities | NA |
PMID | None |
Year of Publication | None |
Tertiary Structure (Technique) | Not Predicted), |
Primary information | |
---|---|
ID | antitb_1300, |
Name | 20483615 |
N-Terminal modification | Trichoderins B |
C-Terminal Modification | (MDA)-P-(AHMOD)-(Aib)-(Aib)-V-V-(Aib)-(Aib)-(AMAE) |
Chemical Modification | Addition of MDA = 2-methyl decanoic acid. |
Linear/Cyclic | Addition of AMAE = 2-[(20-aminopropyl) methylamino] ethanol. |
Length | AHMOD = 2-amino-6-hydroxy-4-methyl-8-oxodecanoic acid, Aib = α-amino- isobutyric acid |
Chirality | Linear |
Nature | 8 |
Source | L |
Species | Natural |
Strain | Isolated from a culture of marine sponge derived fungus of Trichoderma sp. |
Inhibition Concentration | Mycobacterium bovis |
In Vitro/ In vivo | Mycobacterium bovis BCG |
Cell Line | MIC = 0.02 μg/mL |
Inhibition Concentration | In vitro |
Sequence | 2011 |
Cytotoxicity | None |
In vivo Model | NA |
Lethal Dose | NA |
Immune Responce | None |
Mechanism of Action | NA |
Target | NA |
Combination Therapy | NA |
Other activities | NA |
PMID | None |
Year of Publication | None |
Tertiary Structure (Technique) | Not Predicted), |
Primary information | |
---|---|
ID | antitb_1301, |
Name | 20483615 |
N-Terminal modification | Trichoderins B |
C-Terminal Modification | (MDA)-P-(AHMOD)-(Aib)-(Aib)-V-V-(Aib)-(Aib)-(AMAE) |
Chemical Modification | Addition of MDA = 2-methyl decanoic acid. |
Linear/Cyclic | Addition of AMAE = 2-[(20-aminopropyl) methylamino] ethanol. |
Length | AHMOD = 2-amino-6-hydroxy-4-methyl-8-oxodecanoic acid, Aib = α-amino- isobutyric acid |
Chirality | Linear |
Nature | 8 |
Source | L |
Species | Natural |
Strain | Isolated from a culture of marine sponge derived fungus of Trichoderma sp. |
Inhibition Concentration | Mycobacterium tuberculosis |
In Vitro/ In vivo | Mycobacterium tuberculosis H37Rv |
Cell Line | MIC = 0.13 μg/mL |
Inhibition Concentration | In vitro |
Sequence | 2012 |
Cytotoxicity | None |
In vivo Model | NA |
Lethal Dose | NA |
Immune Responce | None |
Mechanism of Action | NA |
Target | NA |
Combination Therapy | NA |
Other activities | NA |
PMID | None |
Year of Publication | None |
Tertiary Structure (Technique) | Not Predicted), |