| Primary information |
|---|
| ID | antitb_1751 |
| Peptide Name | FKAB-1Gd1 |
| Sequence | βAla-F-Tic-Oic-βAla-K-Tic-Oic-βAla-F-Tic-Oic-βAla-K-Tic-KKKK |
| N-terminal Modification | Acetylation |
| C-terminal Modification | Amidation |
| Chemical Modification | βAla = Beta alanine, Tic = tetrahydroisoquinolinecarboxylic acid, Oic = Octahydroindolecarboxylic acid |
| Linear/ Cyclic | Linear |
| Length | 19 |
| Chirality | L |
| Nature | Hydrophobic |
| Source | Synthetic |
| Origin | NA |
| Species | Mycobacterium ranae |
| Strain | Mycobacterium ranae |
| Inhibition Concentartion | MIC = 1 μM |
| In vitro/In vivo | Both |
| Cell Line | RBC |
| Inhibition Concentartion | NA |
| Cytotoxicity | 24.4 % hemolysis at 100 μM and 7.4 % at 25 μM |
| In vivo Model | Mice |
| Lethal Dose | No observed toxicity at 5 and 25 mg/kg but minor w |
| Immune Response | NA |
| Mechanism of Action | NA |
| Target | NA |
| Combination Therapy | None |
| Other Activities | Anti-bacterial (Salmonella typhimurium, Staphylococcus aureus, Bacillus subtillis) |
| Pubmed ID | US 2012/0197004 |
| Year of Publication | 2012 |
| 3-D Structure | NA |