Primary information |
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ID | antitb_1543 |
Peptide Name | RNAse7 |
Sequence | RPPQFTRAQWFAIQHISLMPPRCTIAMRAINNYRWRCKNQNTFLR |
N-terminal Modification | Free |
C-terminal Modification | Free |
Chemical Modification | None |
Linear/ Cyclic | Linear |
Length | 45 |
Chirality | L |
Nature | Cationic |
Source | Protein derived |
Origin | Derived from eisinophilic cationic protein (ECP) |
Species | Mycobacterium vaccae |
Strain | Mycobacterium vaccae |
Inhibition Concentartion | MIC = 10 μg/ml |
In vitro/In vivo | in vitro |
Cell Line | NA |
Inhibition Concentartion | NA |
Cytotoxicity | NA |
In vivo Model | NA |
Lethal Dose | NA |
Immune Response | NA |
Mechanism of Action | Disrupt the mycobacterial membrane |
Target | NA |
Combination Therapy | NA |
Other Activities | Bactericidal against pseudomonas and staphylococcus at pH 5.5 |
Pubmed ID | 25613372 |
Year of Publication | 2015 |
3-D Structure | View in Jmol or Download Structure |