Browse result page of AntiTbPdb
The total number entries retrieved from this search are 24
| ID | Name | Sequence | N-Terminal Modification | C-Terminal Modification | Chemical Modification | Linear/Cyclic | Length | Chirality | Nature | Source | Origin | Species | Strain | Inhibition Concentration | In vitro/ In vivo | Cell Line | Intracellular Inhibition | Cytotoxicity | Animal Model | Effective Dose in model organism | Immune Responce | Mechanism of Action | Target | Combination Therapy | Other Activities | Year of Publication | Pubmed ID/ Patent No. |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| antitb_1256 | Eosinophil Cationic Protein (RNase 3) | RPPQFTRAQWFAIQHISLNPPRCTIAMRAINNYRWRCKNQNTFLRTTFANVVNVCGNQSIRCPHNRTLNN | Free | Free | Disulphide linkage | Cyclic | 70 | L | Cationic | Natural | Secreted by eosinophil secondary granules | Mycobacterium vaccae | Mycobacterium vaccae strain (ATCC 15483) | MIC = 20.0 ± 1.0 μM | In vitro | None | NA | NA | None | NA | NA | Membrane depolarization and permeabilization | Cell envelope | None | Antibacterial and Antiparasitic | 2013 | 23716047 |
| antitb_1257 | Eosinophil Cationic Protein (RNase 3) | RPPQFTRAQWFAIQHISLNPPRCTIAMRAINNYRWRCKNQNTFLRTTFANVVNVCGNQSIRCPHNRTLNN | Free | Free | Disulphide linkage | Cyclic | 70 | L | Cationic | Natural | Secreted by eosinophil secondary granules | Mycobacterium vaccae | Mycobacterium vaccae strain (ATCC 15483) | IC50 = 11.6 ± 0.2 μM | In vitro | None | NA | NA | None | NA | NA | Membrane depolarization and permeabilization | Cell envelope | None | Antibacterial and Antiparasitic | 2013 | 23716047 |
| antitb_1258 | RNase 7 | KPKGMTSSQWFKIQHMOPSPQACNSAMKNINKHTKRCKDLNTFLHEPFSSVAATCQTPKIACKNGDKN | Free | Free | Disulphide linkage | Cyclic | 68 | L | Cationic | Natural | Secreted by innate cells during host defense | Mycobacterium vaccae | Mycobacterium vaccae strain (ATCC 15483) | MIC = 20.0 ± 0.5 μM | In vitro | None | NA | NA | None | NA | NA | Membrane depolarization and permeabilization | Cell envelope | None | Antibacterial and Antiparasitic | 2013 | 23716047 |
| antitb_1259 | RNase 7 | KPKGMTSSQWFKIQHMOPSPQACNSAMKNINKHTKRCKDLNTFLHEPFSSVAATCQTPKIACKNGDKN | Free | Free | Disulphide linkage | Cyclic | 68 | L | Cationic | Natural | Secreted by innate cells during host defense | Mycobacterium vaccae | Mycobacterium vaccae strain (ATCC 15483) | IC50 = 9.3 ± 1.2 μM | In vitro | None | NA | NA | None | NA | NA | Membrane depolarization and permeabilization | Cell envelope | None | Antibacterial and Antiparasitic | 2013 | 23716047 |
| antitb_1260 | RN3 (1-45) | RPPQFTRAQWFAIQHISLNPPRSTIAMRAINNYRWRSKNQNTFLR | Free | Free | None | Linear | 45 | L | Cationic | Protein Derived | From the N terminus of RNase 3 | Mycobacterium vaccae | Mycobacterium vaccae strain (ATCC 15483) | MIC = 10.0 ± 0.5 μM | In vitro | None | NA | NA | None | NA | NA | Membrane depolarization and permeabilization | Cell envelope | None | Antibacterial and Antiparasitic | 2013 | 23716047 |
| antitb_1261 | RN3 (1-45) | RPPQFTRAQWFAIQHISLNPPRSTIAMRAINNYRWRSKNQNTFLR | Free | Free | None | Linear | 45 | L | Cationic | Protein Derived | From the N terminus of RNase 4 | Mycobacterium vaccae | Mycobacterium vaccae strain (ATCC 15483) | IC50 = 4.2 ± 0.2 μM | In vitro | None | NA | NA | None | NA | NA | Membrane depolarization and permeabilization | Cell envelope | None | Antibacterial and Antiparasitic | 2013 | 23716047 |
| antitb_1262 | RN7 (1-45) | KPKGMTSSQWFKIQHMQPSPQASNSAMKNINKHTKRSKDLNTFLH | Free | Free | None | Linear | 45 | L | Cationic | Protein Derived | From the N terminus of RNase 7 | Mycobacterium vaccae | Mycobacterium vaccae strain (ATCC 15483) | MIC = 20.0 ± 0.8 μM | In vitro | None | NA | NA | None | NA | NA | Membrane depolarization and permeabilization | Cell envelope | None | Antibacterial and Antiparasitic | 2013 | 23716047 |
| antitb_1263 | RN7 (1-45) | KPKGMTSSQWFKIQHMQPSPQASNSAMKNINKHTKRSKDLNTFLH | Free | Free | None | Linear | 45 | L | Cationic | Protein Derived | From the N terminus of RNase 8 | Mycobacterium vaccae | Mycobacterium vaccae strain (ATCC 15483) | IC50 = 9.5 ± 0.3 μM | In vitro | None | NA | NA | None | NA | NA | Membrane depolarization and permeabilization | Cell envelope | None | Antibacterial and Antiparasitic | 2013 | 23716047 |
| antitb_1264 | Cecropin A-melittin (CA-M) hybrid peptide | KWKLFKKIGIGAVLKVLTTGLPALIS | Free | Amidation | None | Linear | 26 | L | Cationic | Protein Derived | Hybrid derived from cecropin A-melittin | Mycobacterium vaccae | Mycobacterium vaccae strain (ATCC 15483) | MIC = 20.0 ± 1.0 μM | In vitro | None | NA | NA | None | NA | NA | Membrane depolarization and permeabilization | Cell envelope | None | Antibacterial and Antiparasitic | 2013 | 23716047 |
| antitb_1265 | Cecropin A-melittin (CA-M) hybrid peptide | KWKLFKKIGIGAVLKVLTTGLPALIS | Free | Amidation | None | Linear | 26 | L | Cationic | Protein Derived | Hybrid derived from cecropin A-melittin | Mycobacterium vaccae | Mycobacterium vaccae strain (ATCC 15483) | IC50 = 10.3 ± 0.3 μM | In vitro | None | NA | NA | None | NA | NA | Membrane depolarization and permeabilization | Cell envelope | None | Antibacterial and Antiparasitic | 2013 | 23716047 |
| antitb_1543 | RNAse7 | RPPQFTRAQWFAIQHISLMPPRCTIAMRAINNYRWRCKNQNTFLR | Free | Free | None | Linear | 45 | L | Cationic | Protein derived | Derived from eisinophilic cationic protein (ECP) | Mycobacterium vaccae | Mycobacterium vaccae | MIC = 10 μg/ml | in vitro | NA | NA | NA | NA | NA | NA | Disrupt the mycobacterial membrane | NA | NA | Bactericidal against pseudomonas and staphylococcus at pH 5.5 | 2015 | 25613372 |
| antitb_1998 | Apidaecin Ia acid( A24 C3) | GNNRPVYIPQPRPPHPRI | Free | Free | None | Linear | 18 | L | Cationic | Synthetic | Mycobaclerium vaccae | Mycobacterium vaccae | Mycobacterium vaccae | MIC = >125 | In vitro | NA | NA | NA | NA | NA | NA | NA | NA | NA | Anti bacterial against - Eschericha coli 45849 and D31, - Klebsiella pneumoniae 123132 and K6,Salmonella typhi S5 and Salmonella enterica subsp. enterica serovar Typhimurium, Rhizobium radiobacter, Klebsiella pneumoniae, Bactillus subtillis | 2010 | US 0222268 A1/E |
| antitb_1999 | Api Ib 01 ac.(A18 G5 ac) | ONNRPVYIPQPRPPHPRL | Acetylation | Amidation | None | Linear | 18 | L | Cationic | Synthetic | Mycobaclerium vaccae | Mycobacterium vaccae | Mycobacterium vaccae | MIC = 125 | In vitro | NA | NA | NA | NA | NA | NA | NA | NA | NA | Anti bacterial against - Eschericha coli 45849 and D31, - Klebsiella pneumoniae 123132 and K6,Salmonella typhi S5 and Salmonella enterica subsp. enterica serovar Typhimurium, Rhizobium radiobacter, Klebsiella pneumoniae, Bactillus subtillis | 2010 | US 0222268 A1/E |
| antitb_2000 | Â Api Ib 01 (A18 G5) | ONNRPVYIPQPRPPHPRL | Free | Amidation | None | Linear | 18 | L | Cationic | Synthetic | Mycobaclerium vaccae | Mycobacterium vaccae | Mycobacterium vaccae | MIC = 125 | In vitro | NA | NA | NA | NA | NA | NA | NA | NA | NA | Anti bacterial against - Eschericha coli 45849 and D31, - Klebsiella pneumoniae 123132 and K6,Salmonella typhi S5 and Salmonella enterica subsp. enterica serovar Typhimurium, Rhizobium radiobacter, Klebsiella pneumoniae, Bactillus subtillis | 2010 | US 0222268 A1/E |
| antitb_2001 | Api Ib Ol RlO (Al 8 G6) | ONNRPVYIPRPRPPHPRL | Free | Amidation | None | Linear | 18 | L | Cationic | Synthetic | Mycobaclerium vaccae | Mycobacterium vaccae | Mycobacterium vaccae | MIC = 125 | In vitro | NA | NA | NA | NA | NA | NA | NA | NA | NA | Anti bacterial against - Eschericha coli 45849 and D31, - Klebsiella pneumoniae 123132 and K6,Salmonella typhi S5 and Salmonella enterica subsp. enterica serovar Typhimurium, Rhizobium radiobacter, Klebsiella pneumoniae, Bactillus subtillis | 2010 | US 0222268 A1/E |
| antitb_2002 | Api Ib Ol RlO ac. | ONNRPVYIPRPRPPHPRL | Acetylation | Amidation | None | Linear | 18 | L | Cationic | Synthetic | Mycobaclerium vaccae | Mycobacterium vaccae | Mycobacterium vaccae | MIC = 125 | In vitro | NA | NA | NA | NA | NA | NA | NA | NA | NA | Anti bacterial against - Eschericha coli 45849 and D31, - Klebsiella pneumoniae 123132 and K6,Salmonella typhi S5 and Salmonella enterica subsp. enterica serovar Typhimurium, Rhizobium radiobacter, Klebsiella pneumoniae, Bactillus subtillis | 2010 | US 0222268 A1/E |
| antitb_2003 | Api Ia Ol RlO ac (A18 A2 ac) | ONNRPVYIPRPRPPHPRI | Acetylation | Amidation | None | Linear | 18 | L | Cationic | Synthetic | Mycobaclerium vaccae | Mycobacterium vaccae | Mycobacterium vaccae | MIC = 62.5 | In vitro | NA | NA | NA | NA | NA | NA | NA | NA | NA | Anti bacterial against - Eschericha coli 45849 and D31, - Klebsiella pneumoniae 123132 and K6,Salmonella typhi S5 and Salmonella enterica subsp. enterica serovar Typhimurium, Rhizobium radiobacter, Klebsiella pneumoniae, Bactillus subtillis | 2010 | US 0222268 A1/E |
| antitb_2004 | Api . Ib RlO (Al 8 A5) | GNNRPVYIPRPRPPHPRL | Free | Amidation | None | Linear | 18 | L | Cationic | Synthetic | Mycobaclerium vaccae | Mycobacterium vaccae | Mycobacterium vaccae | MIC = 125 | In vitro | NA | NA | NA | NA | NA | NA | NA | NA | NA | Anti bacterial against - Eschericha coli 45849 and D31, - Klebsiella pneumoniae 123132 and K6,Salmonella typhi S5 and Salmonella enterica subsp. enterica serovar Typhimurium, Rhizobium radiobacter, Klebsiella pneumoniae, Bactillus subtillis | 2010 | US 0222268 A1/E |
| antitb_2005 | Api Ib RlO acety. (A18 A5 ac ) | GNNRPVYIPRPRPPHPRL | Acetylation | Amidation | None | Linear | 18 | L | Cationic | Synthetic | Mycobaclerium vaccae | Mycobacterium vaccae | Mycobacterium vaccae | MIC = 125 | In vitro | NA | NA | NA | NA | NA | NA | NA | NA | NA | Anti bacterial against - Eschericha coli 45849 and D31, - Klebsiella pneumoniae 123132 and K6,Salmonella typhi S5 and Salmonella enterica subsp. enterica serovar Typhimurium, Rhizobium radiobacter, Klebsiella pneumoniae, Bactillus subtillis | 2010 | US 0222268 A1/E |
| antitb_2006 | Api Ib OIO Hyp 11 ( Al 8 B4) | GNNRPVYIPO-4tHyp-RPPHPRL | Free | Amidation | 4tHyp= hydroxyprolin | Linear | 18 | L | Cationic | Synthetic | Mycobaclerium vaccae | Mycobacterium vaccae | Mycobacterium vaccae | MIC = 125 | In vitro | NA | NA | NA | NA | NA | NA | NA | NA | NA | Anti bacterial against - Eschericha coli 45849 and D31, - Klebsiella pneumoniae 123132 and K6,Salmonella typhi S5 and Salmonella enterica subsp. enterica serovar Typhimurium, Rhizobium radiobacter, Klebsiella pneumoniae, Bactillus subtillis | 2010 | US 0222268 A1/E |
| antitb_2007 | Â Api Ia, OIO ( Al 7 A4 ) | GNNRPVYIPOPRPPHPRI | Free | Amidation | None | Linear | 18 | L | Cationic | Synthetic | Mycobaclerium vaccae | Mycobacterium vaccae | Mycobacterium vaccae | MIC = 125 | In vitro | NA | NA | NA | NA | NA | NA | NA | NA | NA | Anti bacterial against - Eschericha coli 45849 and D31, - Klebsiella pneumoniae 123132 and K6,Salmonella typhi S5 and Salmonella enterica subsp. enterica serovar Typhimurium, Rhizobium radiobacter, Klebsiella pneumoniae, Bactillus subtillis | 2010 | US 0222268 A1/E |
| antitb_2008 | Â Api Ia R 10 Hyp 11 (Al 7 B3) | GNNRPVYIPR-4tHyp-RPPHPRI | Free | Amidation | 4tHyp= hydroxyprolin | Linear | 18 | L | Cationic | Synthetic | Mycobaclerium vaccae | Mycobacterium vaccae | Mycobacterium vaccae | MIC = 125 | In vitro | NA | NA | NA | NA | NA | NA | NA | NA | NA | Anti bacterial against - Eschericha coli 45849 and D31, - Klebsiella pneumoniae 123132 and K6,Salmonella typhi S5 and Salmonella enterica subsp. enterica serovar Typhimurium, Rhizobium radiobacter, Klebsiella pneumoniae, Bactillus subtillis | 2010 | US 0222268 A1/E |
| antitb_2009 | Api Ib RlO Hypll (Al 7 B2) | GNNRPVYIPR-41HyP-RPPHPRL | Free | Amidation | 4tHyp= hydroxyprolin | Linear | 18 | L | Cationic | Synthetic | Mycobaclerium vaccae | Mycobacterium vaccae | Mycobacterium vaccae | MIC = 125 | In vitro | NA | NA | NA | NA | NA | NA | NA | NA | NA | Anti bacterial against - Eschericha coli 45849 and D31, - Klebsiella pneumoniae 123132 and K6,Salmonella typhi S5 and Salmonella enterica subsp. enterica serovar Typhimurium, Rhizobium radiobacter, Klebsiella pneumoniae, Bactillus subtillis | 2010 | US 0222268 A1/E |
| antitb_2010 | Api Ib K4 RlO Vl 9 (Al 8 Bl) | GNNKPVYIPRPRPPHPRLV | Free | Amidation | None | Linear | 18 | L | Cationic | Synthetic | Mycobaclerium vaccae | Mycobacterium vaccae | Mycobacterium vaccae | MIC = 125 | In vitro | NA | NA | NA | NA | NA | NA | NA | NA | NA | Anti bacterial against - Eschericha coli 45849 and D31, - Klebsiella pneumoniae 123132 and K6,Salmonella typhi S5 and Salmonella enterica subsp. enterica serovar Typhimurium, Rhizobium radiobacter, Klebsiella pneumoniae, Bactillus subtillis | 2010 | US 0222268 A1/E |