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Browse result page of AntiTbPdb

The total number entries retrieved from this search are 2
IDNameSequenceN-Terminal ModificationC-Terminal ModificationChemical ModificationLinear/CyclicLengthChiralityNatureSourceOriginSpeciesStrainInhibition ConcentrationIn vitro/ In vivoCell LineIntracellular InhibitionCytotoxicityAnimal ModelEffective Dose in model organismImmune ResponceMechanism of ActionTargetCombination TherapyOther ActivitiesYear of PublicationPubmed ID/ Patent No.
antitb_1195Boropentapeptide AVKAA-B(OH)2 FreeConjugated with Boronic acidConjugated with Boronic acidLinear5LNASyntheticNAMycobacterium thermoresistible Mycobacterium thermoresistible Poorer inhibition than Pinanediol PD-protected Boropentapeptide In vitroNoneNANANone NANAInhibit enzyme (MycP1) reponsible for cleavage of virulence factor (ESX secretion-associated protein B (EspB))Mycosin protease-1 (MycP1) NoneNone201424915878
antitb_1198Pinanediol PD-protected Boropentapeptide AVKAA-BO2(PD) FreeConjugated with Boronic acid and pinanediol PDConjugated with Boronic acid and pinanediol PDLinear5LNASyntheticNAMycobacterium thermoresistible Mycobacterium thermoresistible IC50 = 121.6 ± 25.3 μM for MycP1In vitroNoneNANANone NANAInhibit enzyme (MycP1) reponsible for cleavage of virulence factor (ESX secretion-associated protein B (EspB))Mycosin protease-1 (MycP1) NoneNone201424915878