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Browse result page of AntiTbPdb

The total number entries retrieved from this search are 668
IDNameSequenceN-Terminal ModificationC-Terminal ModificationChemical ModificationLinear/CyclicLengthChiralityNatureSourceOriginSpeciesStrainInhibition ConcentrationIn vitro/ In vivoCell LineIntracellular InhibitionCytotoxicityAnimal ModelEffective Dose in model organismImmune ResponceMechanism of ActionTargetCombination TherapyOther ActivitiesYear of PublicationPubmed ID/ Patent No.
antitb_1001Polydim-I AVAGEKLWLLPHLLKMLLTPTPFreeFreeNoneLinear22LAmphipathicNaturalIsolated from the venom of the Neotropical wasp Polybia dimorpha Mycobacterium abscessus subsp. massiliense Mycobacterium abscessus subsp. massiliense isolates GO 01, GO 06, GO 07, GO 08, GO 13, and GO 18, CRM0020 (Mycobacterium abscessus subsp. massiliense), and ATCC19977 (Mycobacterium abscessus subsp. abscessus)MIC = 60.8 μg/mL BothPeritoneal macrophages, J774 macrophages cells, human red blood cells Treatment of infected macrophages with 7.6 μg/mL of Polydim-I decreased approximately 50% of the bacterial load Non-cytotoxic, 10% cytotoxicity on J774 cells at concentrations above 121.6 μg/mL (10%) and concentrations up to 121.6 μg/mL presented less than 2.5% of hemolytic activity6 to 8 weeks old BALB/c and IFN-γKO (Knockout) female mice 2 mg/kg/mLW shows 90% reduction in bacterial loadNACell wall disruption Cell wallNoneNA201626930596
antitb_1025Seq1WKWLKKWIKFreeFreeNoneLinear9LCationicSyntheticNAMycobacterium tuberculosis Mycobacterium tuberculosis H37Rv, and the Mycobacterium tuberculosis lux strain MIC90 = 1.1 μMIn vitroTHP-1 cells NAFor THP-1 (infected wth M.tb) IC50 = 24.3 μMNone NANANANANoneAntibacterial and Antifungal (P. aeruginosa, Escherichia coli, Salmonella enterica serovar Typhimurium, Candida albicans, Streptococcus epidermidis, Staphylococcus aureus, and Enterococcus faecalis)201323478953
antitb_1026Seq1WKWLKKWIKFreeFreeNoneLinear9LCationicSyntheticNAMycobacterium smegmatis Mycobacterium smegmatis mc26 MIC90 = 1.9 μMIn vitroTHP-1 cells NAFor THP-1 (infected wth M.tb) IC90 = 24.3 μMNone NANANANANoneAntibacterial and Antifungal (P. aeruginosa, Escherichia coli, Salmonella enterica serovar Typhimurium, Candida albicans, Streptococcus epidermidis, Staphylococcus aureus, and Enterococcus faecalis)201323478953
antitb_1027Seq2ILRWKWRWWRWRRFreeFreeNoneLinear13LCationicSyntheticNAMycobacterium tuberculosis Mycobacterium tuberculosis H37Rv, and the Mycobacterium tuberculosis lux strain MIC90 = 2.4 μMIn vitroTHP-1 cells NAFor THP-1 (infected wth M.tb) IC50 = 25.2 μMNone NANANANANoneAntibacterial and Antifungal (P. aeruginosa, Escherichia coli, Salmonella enterica serovar Typhimurium, Candida albicans, Streptococcus epidermidis, Staphylococcus aureus, and Enterococcus faecalis)201323478953
antitb_1028Seq2ILRWKWRWWRWRRFreeFreeNoneLinear13LCationicSyntheticNAMycobacterium smegmatis Mycobacterium smegmatis mc26 MIC90 = 2.4 μMIn vitroTHP-1 cells NAFor THP-1 (infected wth M.tb) IC90 = 50.4 μMNone NANANANANoneAntibacterial and Antifungal (P. aeruginosa, Escherichia coli, Salmonella enterica serovar Typhimurium, Candida albicans, Streptococcus epidermidis, Staphylococcus aureus, and Enterococcus faecalis)201323478953
antitb_1029Seq 3ILPWKWRWWKWRRFreeFreeNoneLinear13LCationicSyntheticNAMycobacterium tuberculosis Mycobacterium tuberculosis H37Rv, and the Mycobacterium tuberculosis lux strain MIC90 = 2.6 μMIn vitroTHP-1 cells NAFor THP-1 (infected wth M.tb) IC50 = 56.4 μMNone NANANANANoneAntibacterial and Antifungal (P. aeruginosa, Escherichia coli, Salmonella enterica serovar Typhimurium, Candida albicans, Streptococcus epidermidis, Staphylococcus aureus, and Enterococcus faecalis)201323478953
antitb_1030Seq 3ILPWKWRWWKWRRFreeFreeNoneLinear13LCationicSyntheticNAMycobacterium smegmatis Mycobacterium smegmatis mc26 MIC90 = 2.2 μMIn vitroTHP-1 cells NAFor THP-1 (infected wth M.tb) IC90 = 56.4 μMNone NANANANANoneAntibacterial and Antifungal (P. aeruginosa, Escherichia coli, Salmonella enterica serovar Typhimurium, Candida albicans, Streptococcus epidermidis, Staphylococcus aureus, and Enterococcus faecalis)201323478953
antitb_1031Seq 4RWRRKWWWWFreeFreeNoneLinear9LCationicSyntheticNAMycobacterium tuberculosis Mycobacterium tuberculosis H37Rv, and the Mycobacterium tuberculosis lux strain MIC90 = 2.8 μMIn vitroTHP-1 cells NAFor THP-1 (infected wth M.tb) IC50 = 73.0 μMNone NANANANANoneAntibacterial and Antifungal (P. aeruginosa, Escherichia coli, Salmonella enterica serovar Typhimurium, Candida albicans, Streptococcus epidermidis, Staphylococcus aureus, and Enterococcus faecalis)201323478953
antitb_1032Seq 4RWRRKWWWWFreeFreeNoneLinear9LCationicSyntheticNAMycobacterium smegmatis Mycobacterium smegmatis mc26 MIC90 = 5.7 μMIn vitroTHP-1 cells NAFor THP-1 (infected wth M.tb) IC90 =145.9 μMNone NANANANANoneAntibacterial and Antifungal (P. aeruginosa, Escherichia coli, Salmonella enterica serovar Typhimurium, Candida albicans, Streptococcus epidermidis, Staphylococcus aureus, and Enterococcus faecalis)201323478953
antitb_1033Seq 5WRKFWKYLKFreeFreeNoneLinear9LCationicSyntheticNAMycobacterium tuberculosis Mycobacterium tuberculosis H37Rv, and the Mycobacterium tuberculosis lux strain MIC90 = 3 μMIn vitroTHP-1 cells NAFor THP-1 (infected wth M.tb) IC50 = 47.3 μMNone NANANANANoneAntibacterial and Antifungal (P. aeruginosa, Escherichia coli, Salmonella enterica serovar Typhimurium, Candida albicans, Streptococcus epidermidis, Staphylococcus aureus, and Enterococcus faecalis)201323478953
antitb_1034Seq 5WRKFWKYLKFreeFreeNoneLinear9LCationicSyntheticNAMycobacterium smegmatis Mycobacterium smegmatis mc26 MIC90 = 1.5 μMIn vitroTHP-1 cells NAFor THP-1 (infected wth M.tb) IC90 = 47.3 μMNone NANANANANoneAntibacterial and Antifungal (P. aeruginosa, Escherichia coli, Salmonella enterica serovar Typhimurium, Candida albicans, Streptococcus epidermidis, Staphylococcus aureus, and Enterococcus faecalis)201323478953
antitb_1035Seq 6KRWWKWWRRFreeFreeNoneLinear9LCationicSyntheticNAMycobacterium tuberculosis Mycobacterium tuberculosis H37Rv, and the Mycobacterium tuberculosis lux strain MIC90 = 3.1 μMIn vitroTHP-1 cells NAFor THP-1 (infected wth M.tb) IC50 = 79.2 μMNone NANANANANoneAntibacterial and Antifungal (P. aeruginosa, Escherichia coli, Salmonella enterica serovar Typhimurium, Candida albicans, Streptococcus epidermidis, Staphylococcus aureus, and Enterococcus faecalis)201323478953
antitb_1036Seq 6KRWWKWWRRFreeFreeNoneLinear9LCationicSyntheticNAMycobacterium smegmatis Mycobacterium smegmatis mc26 MIC90 = 4.9 μMIn vitroTHP-1 cells NAFor THP-1 (infected wth M.tb) IC90 = 158.4 μMNone NANANANANoneAntibacterial and Antifungal (P. aeruginosa, Escherichia coli, Salmonella enterica serovar Typhimurium, Candida albicans, Streptococcus epidermidis, Staphylococcus aureus, and Enterococcus faecalis)201323478953
antitb_1037Seq 7RRWWKWWWRFreeFreeNoneLinear9LCationicSyntheticNAMycobacterium tuberculosis Mycobacterium tuberculosis H37Rv, and the Mycobacterium tuberculosis lux strain MIC90 = 3.6 μMIn vitroTHP-1 cells NAFor THP-1 (infected wth M.tb) IC50 = 152.6 μMNone NANANANANoneAntibacterial and Antifungal (P. aeruginosa, Escherichia coli, Salmonella enterica serovar Typhimurium, Candida albicans, Streptococcus epidermidis, Staphylococcus aureus, and Enterococcus faecalis)201323478953
antitb_1038Seq 7RRWWKWWWRFreeFreeNoneLinear9LCationicSyntheticNAMycobacterium smegmatis Mycobacterium smegmatis mc26 MIC90 = 4.8 μMIn vitroTHP-1 cells NAFor THP-1 (infected wth M.tb) IC90 = 152.6 μMNone NANANANANoneAntibacterial and Antifungal (P. aeruginosa, Escherichia coli, Salmonella enterica serovar Typhimurium, Candida albicans, Streptococcus epidermidis, Staphylococcus aureus, and Enterococcus faecalis)201323478953
antitb_1039Seq 8KIWWWWRKRFreeFreeNoneLinear9LCationicSyntheticNAMycobacterium tuberculosis Mycobacterium tuberculosis H37Rv, and the Mycobacterium tuberculosis lux strain MIC90 = 4.1 μMIn vitroTHP-1 cells NAFor THP-1 (infected wth M.tb) IC50 = 173.9 μMNone NANANANANoneAntibacterial and Antifungal (P. aeruginosa, Escherichia coli, Salmonella enterica serovar Typhimurium, Candida albicans, Streptococcus epidermidis, Staphylococcus aureus, and Enterococcus faecalis)201323478953
antitb_1040Seq 8KIWWWWRKRFreeFreeNoneLinear9LCationicSyntheticNAMycobacterium smegmatis Mycobacterium smegmatis mc26 MIC90 = 5.4 μMIn vitroTHP-1 cells NAFor THP-1 (infected wth M.tb) IC90 = 173.9 μMNone NANANANANoneAntibacterial and Antifungal (P. aeruginosa, Escherichia coli, Salmonella enterica serovar Typhimurium, Candida albicans, Streptococcus epidermidis, Staphylococcus aureus, and Enterococcus faecalis)201323478953
antitb_1041Seq 9RLWWWWRRKFreeFreeNoneLinear9LCationicSyntheticNAMycobacterium tuberculosis Mycobacterium tuberculosis H37Rv, and the Mycobacterium tuberculosis lux strain MIC90 = 4.1 μMIn vitroTHP-1 cells NAFor THP-1 (infected wth M.tb) IC50 = 87.0 μMNone NANANANANoneAntibacterial and Antifungal (P. aeruginosa, Escherichia coli, Salmonella enterica serovar Typhimurium, Candida albicans, Streptococcus epidermidis, Staphylococcus aureus, and Enterococcus faecalis)201323478953
antitb_1042Seq 9RLWWWWRRKFreeFreeNoneLinear9LCationicSyntheticNAMycobacterium smegmatis Mycobacterium smegmatis mc26 MIC90 = 2.4 μMIn vitroTHP-1 cells NAFor THP-1 (infected wth M.tb) IC90 = 173.9 μMNone NANANANANoneAntibacterial and Antifungal (P. aeruginosa, Escherichia coli, Salmonella enterica serovar Typhimurium, Candida albicans, Streptococcus epidermidis, Staphylococcus aureus, and Enterococcus faecalis)201323478953
antitb_1043Seq 10KWKWWWRKIFreeFreeNoneLinear9LCationicSyntheticNAMycobacterium tuberculosis Mycobacterium tuberculosis H37Rv, and the Mycobacterium tuberculosis lux strain MIC90 = 4.2 μMIn vitroTHP-1 cells NAFor THP-1 (infected wth M.tb) IC50 = 90.4 μMNone NANANANANoneAntibacterial and Antifungal (P. aeruginosa, Escherichia coli, Salmonella enterica serovar Typhimurium, Candida albicans, Streptococcus epidermidis, Staphylococcus aureus, and Enterococcus faecalis)201323478953
antitb_1044Seq 10KWKWWWRKIFreeFreeNoneLinear9LCationicSyntheticNAMycobacterium smegmatis Mycobacterium smegmatis mc26 MIC90 = 6.4 μMIn vitroTHP-1 cells NAFor THP-1 (infected wth M.tb) IC90 = 90.4 μMNone NANANANANoneAntibacterial and Antifungal (P. aeruginosa, Escherichia coli, Salmonella enterica serovar Typhimurium, Candida albicans, Streptococcus epidermidis, Staphylococcus aureus, and Enterococcus faecalis)201323478953
antitb_1045Seq 11RIRRWKFRWFreeFreeNoneLinear9LCationicSyntheticNAMycobacterium tuberculosis Mycobacterium tuberculosis H37Rv, and the Mycobacterium tuberculosis lux strain MIC90 = 4.3 μMIn vitroTHP-1 cells NAFor THP-1 (infected wth M.tb) IC50 = 182.5 μMNone NANANANANoneAntibacterial and Antifungal (P. aeruginosa, Escherichia coli, Salmonella enterica serovar Typhimurium, Candida albicans, Streptococcus epidermidis, Staphylococcus aureus, and Enterococcus faecalis)201323478953
antitb_1046Seq 11RIRRWKFRWFreeFreeNoneLinear9LCationicSyntheticNAMycobacterium smegmatis Mycobacterium smegmatis mc26 MIC90 = 1.4 μMIn vitroTHP-1 cells NAFor THP-1 (infected wth M.tb) IC90 = 182.5 μMNone NANANANANoneAntibacterial and Antifungal (P. aeruginosa, Escherichia coli, Salmonella enterica serovar Typhimurium, Candida albicans, Streptococcus epidermidis, Staphylococcus aureus, and Enterococcus faecalis)201323478953
antitb_1047Seq 12RLKRWWKFLFreeFreeNoneLinear9LCationicSyntheticNAMycobacterium tuberculosis Mycobacterium tuberculosis H37Rv, and the Mycobacterium tuberculosis lux strain MIC90 = 4.5 μMIn vitroTHP-1 cells NAFor THP-1 (infected wth M.tb) IC50 = 48.0 μMNone NANANANANoneAntibacterial and Antifungal (P. aeruginosa, Escherichia coli, Salmonella enterica serovar Typhimurium, Candida albicans, Streptococcus epidermidis, Staphylococcus aureus, and Enterococcus faecalis)201323478953
antitb_1048Seq 12RLKRWWKFLFreeFreeNoneLinear9LCationicSyntheticNAMycobacterium smegmatis Mycobacterium smegmatis mc26 MIC90 = 3 μMIn vitroTHP-1 cells NAFor THP-1 (infected wth M.tb) IC90 = 48.0 μMNone NANANANANoneAntibacterial and Antifungal (P. aeruginosa, Escherichia coli, Salmonella enterica serovar Typhimurium, Candida albicans, Streptococcus epidermidis, Staphylococcus aureus, and Enterococcus faecalis)201323478953
antitb_1049Seq 13RWWRWRKWWFreeFreeNoneLinear9LCationicSyntheticNAMycobacterium tuberculosis Mycobacterium tuberculosis H37Rv, and the Mycobacterium tuberculosis lux strain MIC90 = 4.6 μMIn vitroTHP-1 cells NAFor THP-1 (infected wth M.tb) IC50 =147.5 μMNone NANANANANoneAntibacterial and Antifungal (P. aeruginosa, Escherichia coli, Salmonella enterica serovar Typhimurium, Candida albicans, Streptococcus epidermidis, Staphylococcus aureus, and Enterococcus faecalis)201323478953
antitb_1050Seq 13RWWRWRKWWFreeFreeNoneLinear9LCationicSyntheticNAMycobacterium smegmatis Mycobacterium smegmatis mc26 MIC90 = 4.6 μMIn vitroTHP-1 cells NAFor THP-1 (infected wth M.tb) IC90 =147.5 μMNone NANANANANoneAntibacterial and Antifungal (P. aeruginosa, Escherichia coli, Salmonella enterica serovar Typhimurium, Candida albicans, Streptococcus epidermidis, Staphylococcus aureus, and Enterococcus faecalis)201323478953
antitb_1051Seq 14KRWWWWRFRFreeFreeNoneLinear9LCationicSyntheticNAMycobacterium tuberculosis Mycobacterium tuberculosis H37Rv, and the Mycobacterium tuberculosis lux strain MIC90 = 5.2 μMIn vitroTHP-1 cells NAFor THP-1 (infected wth M.tb) IC50 = 83.4 μMNone NANANANANoneAntibacterial and Antifungal (P. aeruginosa, Escherichia coli, Salmonella enterica serovar Typhimurium, Candida albicans, Streptococcus epidermidis, Staphylococcus aureus, and Enterococcus faecalis)201323478953
antitb_1052Seq 14KRWWWWRFRFreeFreeNoneLinear9LCationicSyntheticNAMycobacterium smegmatis Mycobacterium smegmatis mc26 MIC90 = 5.2 μMIn vitroTHP-1 cells NAFor THP-1 (infected wth M.tb) IC90 =166.7 μMNone NANANANANoneAntibacterial and Antifungal (P. aeruginosa, Escherichia coli, Salmonella enterica serovar Typhimurium, Candida albicans, Streptococcus epidermidis, Staphylococcus aureus, and Enterococcus faecalis)201323478953
antitb_1053Seq 15KRWWRKWWRFreeFreeNoneLinear9LCationicSyntheticNAMycobacterium tuberculosis Mycobacterium tuberculosis H37Rv, and the Mycobacterium tuberculosis lux strain MIC90 = 5.3 μMIn vitroTHP-1 cells NAFor THP-1 (infected wth M.tb) IC50 = 84.4 μMNone NANANANANoneAntibacterial and Antifungal (P. aeruginosa, Escherichia coli, Salmonella enterica serovar Typhimurium, Candida albicans, Streptococcus epidermidis, Staphylococcus aureus, and Enterococcus faecalis)201323478953
antitb_1054Seq 15KRWWRKWWRFreeFreeNoneLinear9LCationicSyntheticNAMycobacterium smegmatis Mycobacterium smegmatis mc26 MIC90 = 5.3 μMIn vitroTHP-1 cells NAFor THP-1 (infected wth M.tb) IC90 = 84.4 μMNone NANANANANoneAntibacterial and Antifungal (P. aeruginosa, Escherichia coli, Salmonella enterica serovar Typhimurium, Candida albicans, Streptococcus epidermidis, Staphylococcus aureus, and Enterococcus faecalis)201323478953
antitb_1055Seq 16RRWWRWVVWFreeFreeNoneLinear9LCationicSyntheticNAMycobacterium tuberculosis Mycobacterium tuberculosis H37Rv, and the Mycobacterium tuberculosis lux strain MIC90 = 5.6 μMIn vitroTHP-1 cells NAFor THP-1 (infected wth M.tb) IC50 = 179.1 μMNone NANANANANoneAntibacterial and Antifungal (P. aeruginosa, Escherichia coli, Salmonella enterica serovar Typhimurium, Candida albicans, Streptococcus epidermidis, Staphylococcus aureus, and Enterococcus faecalis)201323478953
antitb_1056Seq 16RRWWRWVVWFreeFreeNoneLinear9LCationicSyntheticNAMycobacterium smegmatis Mycobacterium smegmatis mc26 MIC90 = 11.4 μMIn vitroTHP-1 cells NAFor THP-1 (infected wth M.tb) IC90 = 179.1 μMNone NANANANANoneAntibacterial and Antifungal (P. aeruginosa, Escherichia coli, Salmonella enterica serovar Typhimurium, Candida albicans, Streptococcus epidermidis, Staphylococcus aureus, and Enterococcus faecalis)201323478953
antitb_1057Seq 17WFKMRWWGRFreeFreeNoneLinear9LCationicSyntheticNAMycobacterium tuberculosis Mycobacterium tuberculosis H37Rv, and the Mycobacterium tuberculosis lux strain MIC90 = 5.9 μMIn vitroTHP-1 cells NAFor THP-1 (infected wth M.tb) IC50 =189.3 μMNone NANANANANoneAntibacterial and Antifungal (P. aeruginosa, Escherichia coli, Salmonella enterica serovar Typhimurium, Candida albicans, Streptococcus epidermidis, Staphylococcus aureus, and Enterococcus faecalis)201323478953
antitb_1058Seq 17WFKMRWWGRFreeFreeNoneLinear9LCationicSyntheticNAMycobacterium smegmatis Mycobacterium smegmatis mc26 MIC90 = 2.2 μMIn vitroTHP-1 cells NAFor THP-1 (infected wth M.tb) IC90 =189.3 μMNone NANANANANoneAntibacterial and Antifungal (P. aeruginosa, Escherichia coli, Salmonella enterica serovar Typhimurium, Candida albicans, Streptococcus epidermidis, Staphylococcus aureus, and Enterococcus faecalis)201323478953
antitb_1059Seq 18KFKWWRMLIFreeFreeNoneLinear9LCationicSyntheticNAMycobacterium tuberculosis Mycobacterium tuberculosis H37Rv, and the Mycobacterium tuberculosis lux strain MIC90 = 6.1 μMIn vitroTHP-1 cells NAFor THP-1 (infected wth M.tb) IC50 = 49.0 μMNone NANANANANoneAntibacterial and Antifungal (P. aeruginosa, Escherichia coli, Salmonella enterica serovar Typhimurium, Candida albicans, Streptococcus epidermidis, Staphylococcus aureus, and Enterococcus faecalis)201323478953
antitb_1060Seq 18KFKWWRMLIFreeFreeNoneLinear9LCationicSyntheticNAMycobacterium smegmatis Mycobacterium smegmatis mc26 MIC90 = 15.3 μMIn vitroTHP-1 cells NAFor THP-1 (infected wth M.tb) IC90 = 49.0 μMNone NANANANANoneAntibacterial and Antifungal (P. aeruginosa, Escherichia coli, Salmonella enterica serovar Typhimurium, Candida albicans, Streptococcus epidermidis, Staphylococcus aureus, and Enterococcus faecalis)201323478953
antitb_1061Seq 19FIKWKFRWWKWRKFreeFreeNoneLinear13LCationicSyntheticNAMycobacterium tuberculosis Mycobacterium tuberculosis H37Rv, and the Mycobacterium tuberculosis lux strain MIC90 = 7.4 μMIn vitroTHP-1 cells NAFor THP-1 (infected wth M.tb) IC50 = 14.8 μMNone NANANANANoneAntibacterial and Antifungal (P. aeruginosa, Escherichia coli, Salmonella enterica serovar Typhimurium, Candida albicans, Streptococcus epidermidis, Staphylococcus aureus, and Enterococcus faecalis)201323478953
antitb_1062Seq 19FIKWKFRWWKWRKFreeFreeNoneLinear13LCationicSyntheticNAMycobacterium smegmatis Mycobacterium smegmatis mc26 MIC90 = 3.7 μMIn vitroTHP-1 cells NAFor THP-1 (infected wth M.tb) IC90 = 59.1 μMNone NANANANANoneAntibacterial and Antifungal (P. aeruginosa, Escherichia coli, Salmonella enterica serovar Typhimurium, Candida albicans, Streptococcus epidermidis, Staphylococcus aureus, and Enterococcus faecalis)201323478953
antitb_1063Seq 20RIKRWWWWRFreeFreeNoneLinear9LCationicSyntheticNAMycobacterium tuberculosis Mycobacterium tuberculosis H37Rv, and the Mycobacterium tuberculosis lux strain MIC90 = 7.8 μMIn vitroTHP-1 cells NAFor THP-1 (infected wth M.tb) IC50 = 167.2 μMNone NANANANANoneAntibacterial and Antifungal (P. aeruginosa, Escherichia coli, Salmonella enterica serovar Typhimurium, Candida albicans, Streptococcus epidermidis, Staphylococcus aureus, and Enterococcus faecalis)201323478953
antitb_1064Seq 20RIKRWWWWRFreeFreeNoneLinear9LCationicSyntheticNAMycobacterium smegmatis Mycobacterium smegmatis mc26 MIC90 = 4.6 μMIn vitroTHP-1 cells NAFor THP-1 (infected wth M.tb) IC90 = 167.2 μMNone NANANANANoneAntibacterial and Antifungal (P. aeruginosa, Escherichia coli, Salmonella enterica serovar Typhimurium, Candida albicans, Streptococcus epidermidis, Staphylococcus aureus, and Enterococcus faecalis)201323478953
antitb_1065Seq 21RWRWWWRVYFreeFreeNoneLinear9LCationicSyntheticNAMycobacterium tuberculosis Mycobacterium tuberculosis H37Rv, and the Mycobacterium tuberculosis lux strain MIC90 = 8 μMIn vitroTHP-1 cells NAFor THP-1 (infected wth M.tb) IC50 = 171.5 μMNone NANANANANoneAntibacterial and Antifungal (P. aeruginosa, Escherichia coli, Salmonella enterica serovar Typhimurium, Candida albicans, Streptococcus epidermidis, Staphylococcus aureus, and Enterococcus faecalis)201323478953
antitb_1066Seq 21RWRWWWRVYFreeFreeNoneLinear9LCationicSyntheticNAMycobacterium smegmatis Mycobacterium smegmatis mc26 MIC90 = 6.7 μMIn vitroTHP-1 cells NAFor THP-1 (infected wth M.tb) IC90 = 171.5 μMNone NANANANANoneAntibacterial and Antifungal (P. aeruginosa, Escherichia coli, Salmonella enterica serovar Typhimurium, Candida albicans, Streptococcus epidermidis, Staphylococcus aureus, and Enterococcus faecalis)201323478953
antitb_1067Seq 22HQFRFRFRVRRKFreeFreeNoneLinear12LCationicSyntheticNAMycobacterium tuberculosis Mycobacterium tuberculosis H37Rv, and the Mycobacterium tuberculosis lux strain MIC90 = 8.2 μMIn vitroTHP-1 cells NAFor THP-1 (infected wth M.tb) IC50 = 65.8 μMNone NANANANANoneAntibacterial and Antifungal (P. aeruginosa, Escherichia coli, Salmonella enterica serovar Typhimurium, Candida albicans, Streptococcus epidermidis, Staphylococcus aureus, and Enterococcus faecalis)201323478953
antitb_1068Seq 22HQFRFRFRVRRKFreeFreeNoneLinear12LCationicSyntheticNAMycobacterium smegmatis Mycobacterium smegmatis mc26 MIC90 = 4.1 μMIn vitroTHP-1 cells NAFor THP-1 (infected wth M.tb) IC90 = 131.7 μMNone NANANANANoneAntibacterial and Antifungal (P. aeruginosa, Escherichia coli, Salmonella enterica serovar Typhimurium, Candida albicans, Streptococcus epidermidis, Staphylococcus aureus, and Enterococcus faecalis)201323478953
antitb_1069Seq 23LKRRWKWWIFreeFreeNoneLinear9LCationicSyntheticNAMycobacterium tuberculosis Mycobacterium tuberculosis H37Rv, and the Mycobacterium tuberculosis lux strain MIC90 = 8.8 μMIn vitroTHP-1 cells NAFor THP-1 (infected wth M.tb) IC50 = 186.7 μMNone NANANANANoneAntibacterial and Antifungal (P. aeruginosa, Escherichia coli, Salmonella enterica serovar Typhimurium, Candida albicans, Streptococcus epidermidis, Staphylococcus aureus, and Enterococcus faecalis)201323478953
antitb_1070Seq 23LKRRWKWWIFreeFreeNoneLinear9LCationicSyntheticNAMycobacterium smegmatis Mycobacterium smegmatis mc26 MIC90 = 5.1 μMIn vitroTHP-1 cells NAFor THP-1 (infected wth M.tb) IC90 = 186.7 μMNone NANANANANoneAntibacterial and Antifungal (P. aeruginosa, Escherichia coli, Salmonella enterica serovar Typhimurium, Candida albicans, Streptococcus epidermidis, Staphylococcus aureus, and Enterococcus faecalis)201323478953
antitb_1071Seq 24RRRIKIRWYFreeFreeNoneLinear9LCationicSyntheticNAMycobacterium tuberculosis Mycobacterium tuberculosis H37Rv, and the Mycobacterium tuberculosis lux strain MIC90 = 8.9 μMIn vitroTHP-1 cells NAFor THP-1 (infected wth M.tb) IC50 = 190.2 μMNone NANANANANoneAntibacterial and Antifungal (P. aeruginosa, Escherichia coli, Salmonella enterica serovar Typhimurium, Candida albicans, Streptococcus epidermidis, Staphylococcus aureus, and Enterococcus faecalis)201323478953
antitb_1072Seq 24RRRIKIRWYFreeFreeNoneLinear9LCationicSyntheticNAMycobacterium smegmatis Mycobacterium smegmatis mc26 MIC90 = 1.5 μMIn vitroTHP-1 cells NAFor THP-1 (infected wth M.tb) IC90 = 190.2 μMNone NANANANANoneAntibacterial and Antifungal (P. aeruginosa, Escherichia coli, Salmonella enterica serovar Typhimurium, Candida albicans, Streptococcus epidermidis, Staphylococcus aureus, and Enterococcus faecalis)201323478953
antitb_1073Seq 25RLWWKIWLKFreeFreeNoneLinear9LCationicSyntheticNAMycobacterium tuberculosis Mycobacterium tuberculosis H37Rv, and the Mycobacterium tuberculosis lux strain MIC90 = 9 μMIn vitroTHP-1 cells NAFor THP-1 (infected wth M.tb) IC50 = 192.8 μMNone NANANANANoneAntibacterial and Antifungal (P. aeruginosa, Escherichia coli, Salmonella enterica serovar Typhimurium, Candida albicans, Streptococcus epidermidis, Staphylococcus aureus, and Enterococcus faecalis)201323478953