2SAK | Plasminogen Activator | date | Feb 20, 1997 ![]() ![]() |
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title | Staphylokinase (Sakstar Variant) | ||||||||||||||
authors | A.Rabijns, H.L.De Bondt, M.De Maeyer, I.Lasters, C.De Ranter | ||||||||||||||
compound | source | ||||||||||||||
Molecule: Staphylokinase Chain: A Mutation: Yes |
Organism_scientific: Staphylococcus Aureus | ||||||||||||||
symmetry | Space Group: C 1 2 1 | R_factor | 0.181 | ||||||||||||
crystal cell |
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method | X-Ray Diffraction | resolution | 1.80 Å | ||||||||||||
ligand | TRS | enzyme |
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note | 2SAK is a representative structure | ||||||||||||||
related structures | by homologous chain: 1C76 | ||||||||||||||
similarity | Belongs to the Staphylokinase family. | ||||||||||||||
subcellular loc. | Secreted protein. | ||||||||||||||
Gene | SAK (S. aureus) | ||||||||||||||
function | Potent plasminogen activator that converts plasminogen into plasmin. It forms a 1. 1 complex with plasmin, which in turn activates other plasminogen molecules. | ||||||||||||||
Gene Ontology |
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Primary reference | Three-dimensional structure of staphylokinase, a plasminogen activator with therapeutic potential., Rabijns A, De Bondt HL, De Ranter C, Nat Struct Biol 1997 May;4(5):357-60. PMID:9145104 |
Data retrieval |
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View 2SAK in 3D |
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Visual 3D analysis of 2SAK |
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Structure-derived information |
- Domain d2sak__, region [Jmol] [rasmolscript] [script source] |
Sequence-derived information |
Other resources with information on 2SAK |
Movements, Movies and Images |