2QIL	Staphylococcal Enterotoxin	date	Mar 27, 1997
title	Toxic Shock Syndrome Toxin-1 At 2.07 A Resolution
authors	K.R.Acharya, A.C.Papageorgiou
compound		source
Molecule: Toxic Shock Syndrome Toxin-1 Chain: A, B, C Synonym: Tsst-1		Organism_scientific: Staphylococcus Aureus Strain: Mn8
symmetry	Space Group: C 2 2 21	R_factor	0.204
crystal cell	length a length b length c angle alpha angle beta angle gamma 109.560 177.600 98.130 90.00 90.00 90.00
method	X-Ray Diffraction	resolution	2.07 Å
related structures	by homologous chain: 1TS2, 2TSS
similarity	Belongs to the staphylococcal/streptococcal toxin family.[Stap_Strp_toxin]
subcellular loc.	Secreted protein.
Gene	TST (S. aureus)
function	Responsible for the symptoms of toxic shock syndrome.
Gene Ontology	Chain Function Process Component A, C, B pathogenesis extracellular region
Primary reference	The refined crystal structure of toxic shock syndrome toxin-1 at 2.07 A resolution., Papageorgiou AC, Brehm RD, Leonidas DD, Tranter HS, Acharya KR, J Mol Biol 1996 Jul 26;260(4):553-69. PMID:8759320

Data retrieval

Asymmetric unit, PDB entry: [header only] [complete with coordinates] (101 Kb) [Save to disk] Biological Unit Coordinates (2qil.pdb1.gz) 37 Kb Biological Unit Coordinates (2qil.pdb2.gz) 33 Kb Biological Unit Coordinates (2qil.pdb3.gz) 33 Kb CSU: Contacts of Structural Units for 2QIL Likely Quarternary Molecular Structure file(s) for 2QIL Retrieve 2QIL in mmCIF format [Save to disk]

View 2QIL in 3D

Proteopedia, because life has more than 2D. On Jmol, a nice Rasmol like molecule viewer. This is good for easiest viewing of basic structure. On FirstGlance, an excellent tool for a guided tour on the structure components, by E. Martz. On AstexViewer, from MSD-EBI (viewer documentation). On RasMol (Install RasMol freeware) Here's help on how to use RasMol.

Visual 3D analysis of 2QIL

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Structure-derived information

Dipole moment, from Dipole Server at Weizmann Institute Crystal Contacts, from CryCo at Weizmann Institute 3D motif for 2QIL, from MSDmotif at EBI Genome occurence of 2QIL's fold from GeneCensus Classification of representative domains in scop (Structural Classification of Proteins)     - Domain d2qila1, region A:1-93 [Jmol] [rasmolscript] [script source]     - Domain d2qila2, region A:94-194 [Jmol] [rasmolscript] [script source]     - Domain d2qilb1, region B:1-93 [Jmol] [rasmolscript] [script source]     - Domain d2qilb2, region B:94-194 [Jmol] [rasmolscript] [script source]     - Domain d2qilc1, region C:1-93 [Jmol] [rasmolscript] [script source]     - Domain d2qilc2, region C:94-194 [Jmol] [rasmolscript] [script source] Fold representative 2qil from FSSP and Dali (Families of Structurally Similar Proteins) Class (fold), Architecture (subfold), Topology, Homologous superfamily from CATH Summaries and structural analyses of PDB data files from PDBSum Identification of Protein Pockets & Cavities at CASTp

Sequence-derived information

View one-letter amino acid or nucleotide sequence for each chain: [2qil_A] [2qil_B] [2qil_C]

Other resources with information on 2QIL

InterPro: IPR006125 , IPR006123 , IPR006173 , IPR006126 PDBREPORT (protein verification by WHAT_CHECK procedures) MMDB (Entrez's Structure Database)

Movements, Movies and Images

Domain movements in 2QIL from the Database of Macromolecular Movements. Images from IMB Jena Image Library of Biological Macromolecules.

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