2GDC | Cell Invasion | date | Mar 15, 2006 ![]() ![]() |
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title | Structure Of Vinculin Vd1 Ipaa560-633 Complex | ||||||||||||||
authors | C.Hamiaux, A.Van Eerde, C.Parsot, J.Broos, B.W.Dijkstra | ||||||||||||||
compound | source | ||||||||||||||
Molecule: Vinculin Chain: A Fragment: Vd1 Domain (Residues 0-265) Synonym: Metavinculin Engineered: Yes |
Organism_scientific: Gallus Gallus Organism_common: Chicken Gene: Vcl, Vinc1 Expression_system: Escherichia Coli Expression_system_common: Bacteria Expression_system_strain: Rosetta2 Expression_system_vector_type: Plasmid Expression_system_plasmid: Pmal-P2 | ||||||||||||||
Molecule: Invasin Ipaa Chain: B Fragment: C-Terminal Fragment (Residues 560-633) Synonym: 70 Kda Antigen Engineered: Yes |
Organism_scientific: Shigella Flexneri Organism_common: Bacteria Gene: Ipaa Expression_system: Escherichia Coli Expression_system_common: Bacteria Expression_system_strain: Dh5alpha Expression_system_vector_type: Plasmid Expression_system_plasmid: Pgex4t2 | ||||||||||||||
symmetry | Space Group: P 21 21 2 | R_factor | 0.247 | ||||||||||||
crystal cell |
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method | X-Ray Diffraction | resolution | 2.74 Å | ||||||||||||
Genes | CP0125, IPAA (S. flexneri); VCL, VINC1 (G. gallus) | ||||||||||||||
Gene Ontology | |||||||||||||||
Primary reference | Structural mimicry for vinculin activation by IpaA, a virulence factor of Shigella flexneri., Hamiaux C, van Eerde A, Parsot C, Broos J, Dijkstra BW, EMBO Rep. 2006 Aug;7(8):794-9. Epub 2006 Jul 7. PMID:16826238 |
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