2BVC	Ligase	date	Jun 22, 2005
title	Crystal Structure Of Mycobacterium Tuberculosis Glutamine Synthetase In Complex With A Transition State Mimic
authors	W.W.Krajewski, T.A.Jones, S.L.Mowbray
compound		source
Molecule: Glutamine Synthetase 1 Synonym: Glutamate Ammonia Ligase 1 Chain: A, B, C, D, E, F Ec: 6.3.1.2 Engineered: Yes		Expression_system: Escherichia Coli Expression_system_strain: Bl21-Ai Expression_system_plasmid: Pcr T7ct-Topo Organism_scientific: Mycobacterium Tuberculosis Strain: H37rv
symmetry	Space Group: C 2 2 21	R_factor	0.19140
crystal cell	length a length b length c angle alpha angle beta angle gamma 133.261 229.457 203.167 90.00 90.00 90.00
method	X-Ray Diffraction	resolution	2.1 Å
ligand	ADP, CL, MG, P3S	enzyme	Ligase E.C.6.3.1.2 BRENDA
note	2BVC is a representative structure
Gene Ontology	Chain Function Process Component F, A, D, C, E, B nucleotide binding glutamate-ammonia ligase act... ligase activity glutamine biosynthetic proce... nitrogen compound metabolic ... nitrogen fixation cytoplasm

Data retrieval

Asymmetric unit, PDB entry: [header only] [complete with coordinates] (518 Kb) [Save to disk] Biological Unit Coordinates (2bvc.pdb1.gz) 911 Kb CSU: Contacts of Structural Units for 2BVC Likely Quarternary Molecular Structure file(s) for 2BVC Structure Factors (1348 Kb) Retrieve 2BVC in mmCIF format [Save to disk]

View 2BVC in 3D

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Structure-derived information

Electron Density related parameters from EDS Electron Density Server, at Upsala Dipole moment, from Dipole Server at Weizmann Institute Crystal Contacts, from CryCo at Weizmann Institute 3D motif for 2BVC, from MSDmotif at EBI Fold representative 2bvc from FSSP and Dali (Families of Structurally Similar Proteins)

Sequence-derived information

View one-letter amino acid or nucleotide sequence for each chain: [2bvc_A] [2bvc_B] [2bvc_D] [2bvc_C] [2bvc_F] [2bvc_E]

Other resources with information on 2BVC

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