2B36	Oxidoreductase	date	Sep 19, 2005
title	Crystal Structure Of Mycobacterium Tuberculosis Enoyl Reductase (Inha) Inhibited By 5-Pentyl-2-Phenoxyphenol
authors	T.J.Sullivan, J.J.Truglio, P.Novichenok, C.Stratton, X.Zhang, T.Kaur, F.Johnson, M.S.Boyne, A.Amin
compound		source
Molecule: Enoyl-[Acyl-Carrier-Protein] Reductase [Nadh] Chain: A, B, C, D, E, F Synonym: Nadh-Dependent Enoyl-Acp Reductase Ec: 1.3.1.9 Engineered: Yes		Organism_scientific: Mycobacterium Tuberculosis Gene: Inha Expression_system: Escherichia Coli Expression_system_common: Bacteria
symmetry	Space Group: C 1 2 1	R_factor	0.242
crystal cell	length a length b length c angle alpha angle beta angle gamma 99.955 81.827 188.656 90.00 95.69 90.00
method	X-Ray Diffraction	resolution	2.80 Å
ligand	5PP, NAD	enzyme	Oxidoreductase E.C.1.3.1.9 BRENDA
Gene Ontology	Chain Function Process Component F, A, D, C, E, B enoyl-[acyl-carrier-protein]... oxidoreductase activity fatty acid biosynthetic proc... metabolic process lipid biosynthetic process response to antibiotic

Data retrieval

Asymmetric unit, PDB entry: [header only] [complete with coordinates] (271 Kb) [Save to disk] Biological Unit Coordinates (2b36.pdb1.gz) 164 Kb Biological Unit Coordinates (2b36.pdb2.gz) 160 Kb CSU: Contacts of Structural Units for 2B36 Likely Quarternary Molecular Structure file(s) for 2B36 Structure Factors (869 Kb) Retrieve 2B36 in mmCIF format [Save to disk]

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Structure-derived information

Electron Density related parameters from EDS Electron Density Server, at Upsala Dipole moment, from Dipole Server at Weizmann Institute Crystal Contacts, from CryCo at Weizmann Institute 3D motif for 2B36, from MSDmotif at EBI Fold representative 2b36 from FSSP and Dali (Families of Structurally Similar Proteins)

Sequence-derived information

View one-letter amino acid or nucleotide sequence for each chain: [2b36_D] [2b36_A] [2b36_F] [2b36_E] [2b36_C] [2b36_B]

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