1YWM	Surface Active Protein	date	Feb 18, 2005
title	Crystal Structure Of The N-Terminal Domain Of Group B Streptococcus Alpha C Protein
authors	T.C.Auperin, G.R.Bolduc, M.J.Baron, A.Heroux, D.J.Filman, L.C.Madoff, J.M.Hogle
compound		source
Molecule: C Protein Alpha-Antigen Chain: A Fragment: N-Terminal Domain Engineered: Yes		Organism_scientific: Streptococcus Agalactiae Strain: A909 Gene: Bca Expression_system: Escherichia Coli Expression_system_common: Bacteria Expression_system_strain: Bl21 (De3) Expression_system_vector_type: Plasmid Expression_system_plasmid: Pet24a
symmetry	Space Group: P 61 2 2	R_factor	0.188
crystal cell	length a length b length c angle alpha angle beta angle gamma 56.464 56.464 271.617 90.00 90.00 120.00
method	X-Ray Diffraction	resolution	1.86 Å
ligand	DTU, GOL	enzyme
note	1YWM is a representative structure
similarity	Belongs to the Gram_pos_anchor family.
subcellular loc.	Attached to the cell wall peptidoglycan by an amide bond (potential).
Gene	BCA (S. agalactiae); SAK (S. agalactiae)
function	May play a role in both virulence and immunity.
Gene Ontology	Chain Function Process Component A pathogenesis cell wall cell surface membrane
Primary reference	Crystal Structure of the N-terminal Domain of the Group B Streptococcus Alpha C Protein., Auperin TC, Bolduc GR, Baron MJ, Heroux A, Filman DJ, Madoff LC, Hogle JM, J Biol Chem 2005 May 6;280(18):18245-52. Epub 2005 Mar 6. PMID:15753100

Data retrieval

Asymmetric unit, PDB entry: [header only] [complete with coordinates] (39 Kb) [Save to disk] Biological Unit Coordinates (1ywm.pdb1.gz) 35 Kb CSU: Contacts of Structural Units for 1YWM Likely Quarternary Molecular Structure file(s) for 1YWM Structure Factors (496 Kb) Retrieve 1YWM in mmCIF format [Save to disk]

View 1YWM in 3D

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Structure-derived information

Electron Density related parameters from EDS Electron Density Server, at Upsala Dipole moment, from Dipole Server at Weizmann Institute Crystal Contacts, from CryCo at Weizmann Institute 3D motif for 1YWM, from MSDmotif at EBI Fold representative 1ywm from FSSP and Dali (Families of Structurally Similar Proteins)

Sequence-derived information

View one-letter amino acid or nucleotide sequence for each chain: [1ywm_A]

Other resources with information on 1YWM

InterPro: IPR001899 , IPR012706 , IPR005877 PDBREPORT (protein verification by WHAT_CHECK procedures) MMDB (Entrez's Structure Database)

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