1YQY	Hydrolase	date	Feb 02, 2005
title	Structure Of B. Anthrax Lethal Factor In Complex With A Hydroxamate Inhibitor
authors	W.L.Shoop, Y.Xiong, J.Wiltsie, A.Woods, J.Guo, J.V.Pivnichny, T.Felcetto, B.F.Michael, A.Bansal
compound		source
Molecule: Lethal Factor Chain: A Fragment: Domains II-Iv (Residues 297-809) Synonym: Lf, Anthrax Lethal Toxin Endopeptidase Component Ec: 3.4.24.83 Engineered: Yes		Organism_scientific: Bacillus Anthracis Organism_common: Bacteria Gene: Lef Expression_system: Escherichia Coli Expression_system_common: Bacteria Expression_system_strain: Bl21(De3) Expression_system_vector_type: Plasmid Expression_system_plasmid: Pgex-4t-3
symmetry	Space Group: P 21 21 21	R_factor	0.191
crystal cell	length a length b length c angle alpha angle beta angle gamma 57.332 75.957 139.006 90.00 90.00 90.00
method	X-Ray Diffraction	resolution	2.30 Å
ligand	915, ZN	enzyme	Hydrolase E.C.3.4.24.83 BRENDA
note	1YQY is a representative structure
Gene Ontology	Chain Function Process Component A peptidase activity metallopeptidase activity zinc ion binding hydrolase activity metal ion binding proteolysis pathogenesis extracellular region

Data retrieval

Asymmetric unit, PDB entry: [header only] [complete with coordinates] (107 Kb) [Save to disk] Biological Unit Coordinates (1yqy.pdb1.gz) 94 Kb CSU: Contacts of Structural Units for 1YQY Likely Quarternary Molecular Structure file(s) for 1YQY Structure Factors (205 Kb) Retrieve 1YQY in mmCIF format [Save to disk]

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Structure-derived information

Electron Density related parameters from EDS Electron Density Server, at Upsala Dipole moment, from Dipole Server at Weizmann Institute Crystal Contacts, from CryCo at Weizmann Institute 3D motif for 1YQY, from MSDmotif at EBI Fold representative 1yqy from FSSP and Dali (Families of Structurally Similar Proteins)

Sequence-derived information

View one-letter amino acid or nucleotide sequence for each chain: [1yqy_A]

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