1XF1	Hydrolase	date	Sep 13, 2004
title	Structure Of C5a Peptidase- A Key Virulence Factor From Streptococcus
authors	C.K.Brown, Z.Y.Gu, P.P.Cleary, Y.Matsuka, S.Olmstead, D.H.Ohlendorf, C.A.Earhart
compound		source
Molecule: C5a Peptidase Chain: A, B Synonym: Scp Ec: 3.4.21.- Engineered: Yes		Organism_scientific: Streptococcus Pyogenes Organism_common: Bacteria Gene: Scpa Expression_system: Escherichia Coli Expression_system_common: Bacteria
symmetry	Space Group: P 1 21 1	R_factor	0.229
crystal cell	length a length b length c angle alpha angle beta angle gamma 114.696 75.113 132.391 90.00 104.95 90.00
method	X-Ray Diffraction	resolution	1.90 Å
ligand	ACT, CA, CIT, MSE	enzyme	Hydrolase E.C.3.4.21 BRENDA
note	1XF1 is a representative structure
Gene	SCPA (S. pyogenes)
Gene Ontology	Chain Function Process Component A, B serine-type endopeptidase ac... subtilase activity peptidase activity hydrolase activity proteolysis pathogenesis cell wall cell surface membrane

Data retrieval

Asymmetric unit, PDB entry: [header only] [complete with coordinates] (320 Kb) [Save to disk] Biological Unit Coordinates (1xf1.pdb1.gz) 315 Kb CSU: Contacts of Structural Units for 1XF1 Likely Quarternary Molecular Structure file(s) for 1XF1 Retrieve 1XF1 in mmCIF format [Save to disk]

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Structure-derived information

Dipole moment, from Dipole Server at Weizmann Institute Crystal Contacts, from CryCo at Weizmann Institute 3D motif for 1XF1, from MSDmotif at EBI Fold representative 1xf1 from FSSP and Dali (Families of Structurally Similar Proteins)

Sequence-derived information

View one-letter amino acid or nucleotide sequence for each chain: [1xf1_B] [1xf1_A]

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