1TS5 | Toxin | date | Oct 10, 1997 ![]() ![]() |
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title | I140t Mutant Of Toxic Shock Syndrome Toxin-1 From S. Aureus | ||||||||||||||
authors | C.A.Earhart, D.T.Mitchell, D.L.Murray, D.M.Pinheiro, M.Matsumura, P.M.Schlievert, D.H.Ohlendorf | ||||||||||||||
compound | source | ||||||||||||||
Molecule: Toxic Shock Syndrome Toxin-1 Chain: A, B Synonym: Tsst-1 Engineered: Yes Mutation: Yes |
Organism_scientific: Staphylococcus Aureus Expression_system: Staphylococcus Aureus | ||||||||||||||
symmetry | Space Group: P 61 | R_factor | 0.179 | ||||||||||||
crystal cell |
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method | X-Ray Diffraction | resolution | 3.10 Å | ||||||||||||
similarity | Belongs to the staphylococcal/streptococcal toxin family.[Stap_Strp_toxin] | ||||||||||||||
subcellular loc. | Secreted protein. | ||||||||||||||
Gene | TST (S. aureus) | ||||||||||||||
function | Responsible for the symptoms of toxic shock syndrome. | ||||||||||||||
Gene Ontology |
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Primary reference | Structures of five mutants of toxic shock syndrome toxin-1 with reduced biological activity., Earhart CA, Mitchell DT, Murray DL, Pinheiro DM, Matsumura M, Schlievert PM, Ohlendorf DH, Biochemistry 1998 May 19;37(20):7194-202. PMID:9585531 |
Data retrieval |
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View 1TS5 in 3D |
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Visual 3D analysis of 1TS5 |
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Structure-derived information |
- Domain d1ts5a1, region A:1-93 [Jmol] [rasmolscript] [script source] - Domain d1ts5a2, region A:94-194 [Jmol] [rasmolscript] [script source] - Domain d1ts5b1, region B:201-293 [Jmol] [rasmolscript] [script source] - Domain d1ts5b2, region B:294-394 [Jmol] [rasmolscript] [script source] |
Sequence-derived information |
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