1T13 | Transferase | date | Apr 15, 2004 ![]() ![]() |
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title | Crystal Structure Of Lumazine Synthase From Brucella Abortus Bound To 5-Nitro-6-(D-Ribitylamino)-2,4(1h,3h) Pyrimidinedione | ||||||||||||||
authors | S.Klinke, V.Zylberman, D.R.Vega, B.G.Guimaraes, B.C.Braden, F.A.Goldbaum | ||||||||||||||
compound | source | ||||||||||||||
Molecule: 6,7-Dimethyl-8-Ribityllumazine Synthase Chain: A, B, C, D, E Synonym: Dmrl Synthase, Lumazine Synthase, Riboflavin Synthase Beta Chain; Ec: 2.5.1.9 Engineered: Yes |
Organism_scientific: Brucella Melitensis Biovar Abortus Organism_common: Bacteria Gene: Ribh, Bmeii0589, Bra0695 Expression_system: Escherichia Coli Expression_system_common: Bacteria Expression_system_strain: Bl21(De3) Expression_system_vector_type: Plasmid Expression_system_plasmid: Pet11b | ||||||||||||||
symmetry | Space Group: P 31 2 1 | R_factor | 0.217 | ||||||||||||
crystal cell |
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method | X-Ray Diffraction | resolution | 2.90 Å | ||||||||||||
ligand | INI, PO4 | enzyme | Transferase E.C.2.5.1.9 BRENDA | ||||||||||||
related structures | by homologous chain: 1DI0 | ||||||||||||||
Gene Ontology |
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Primary reference | Crystallographic Studies on Decameric Brucella spp. Lumazine Synthase: A Novel Quaternary Arrangement Evolved for a New Function?, Klinke S, Zylberman V, Vega DR, Guimaraes BG, Braden BC, Goldbaum FA, J Mol Biol 2005 Oct 14;353(1):124-37. PMID:16165152 |
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