1STE	Enterotoxin	date	Aug 21, 1995
title	Staphylococcal Enterotoxin C2 From Staphylococcus Aureus
authors	K.R.Acharya, A.C.Papageorgiou
compound		source
Molecule: Staphylococcal Enterotoxin C2 Chain: A Synonym: Sec2		Organism_scientific: Staphylococcus Aureus
symmetry	Space Group: P 43 21 2	R_factor	0.205
crystal cell	length a length b length c angle alpha angle beta angle gamma 43.050 43.050 290.000 90.00 90.00 90.00
method	X-Ray Diffraction	resolution	2.00 Å
ligand	ZN	enzyme
related structures	by homologous chain: 1I4P, 1UNS
similarity	Belongs to the staphylococcal/streptococcal toxin family.[Stap_Strp_tox_C]
subcellular loc.	Secreted protein.
Gene	ENTC2 (S. aureus)
function	The illness characterized by high fever, hypotension, diarrhea, shock, and in some cases death. Staphylococcal enterotoxins cause the intoxication staphylococcal food poisoning syndrome.
Gene Ontology	Chain Function Process Component A pathogenesis extracellular region
Primary reference	Crystal structure of the superantigen enterotoxin C2 from Staphylococcus aureus reveals a zinc-binding site., Papageorgiou AC, Acharya KR, Shapiro R, Passalacqua EF, Brehm RD, Tranter HS, Structure 1995 Aug 15;3(8):769-79. PMID:7582894

Data retrieval

Asymmetric unit, PDB entry: [header only] [complete with coordinates] (44 Kb) [Save to disk] Biological Unit Coordinates (1ste.pdb1.gz) 41 Kb CSU: Contacts of Structural Units for 1STE Likely Quarternary Molecular Structure file(s) for 1STE Retrieve 1STE in mmCIF format [Save to disk]

View 1STE in 3D

Proteopedia, because life has more than 2D. On Jmol, a nice Rasmol like molecule viewer. This is good for easiest viewing of basic structure. On FirstGlance, an excellent tool for a guided tour on the structure components, by E. Martz. On AstexViewer, from MSD-EBI (viewer documentation). On RasMol (Install RasMol freeware) Here's help on how to use RasMol.

Visual 3D analysis of 1STE

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Structure-derived information

Dipole moment, from Dipole Server at Weizmann Institute Crystal Contacts, from CryCo at Weizmann Institute 3D motif for 1STE, from MSDmotif at EBI Genome occurence of 1STE's fold from GeneCensus Classification of representative domains in scop (Structural Classification of Proteins)     - Domain d1ste_1, region 1-120 [Jmol] [rasmolscript] [script source]     - Domain d1ste_2, region 121-238 [Jmol] [rasmolscript] [script source] Fold representative 1ste from FSSP and Dali (Families of Structurally Similar Proteins) Class (fold), Architecture (subfold), Topology, Homologous superfamily from CATH Summaries and structural analyses of PDB data files from PDBSum Identification of Protein Pockets & Cavities at CASTp

Sequence-derived information

View one-letter amino acid or nucleotide sequence for each chain: [1ste_A]

Other resources with information on 1STE

InterPro: IPR006123 , IPR006173 , IPR006177 , IPR006126 PDBREPORT (protein verification by WHAT_CHECK procedures) MMDB (Entrez's Structure Database)

Movements, Movies and Images

Domain movements in 1STE from the Database of Macromolecular Movements. Images from IMB Jena Image Library of Biological Macromolecules.

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