1SSN	Hydrolase	date	Jun 07, 1998
title	Staphylokinase, Sakstar Variant, Nmr, 20 Structures
authors	O.Ohlenschlager, R.Ramachandran, K.H.Guhrs, B.Schlott, L.R.Brown
compound		source
Molecule: Staphylokinase Chain: A Synonym: Sak Engineered: Yes Mutation: Yes		Organism_scientific: Staphylococcus Aureus Gene: Taq Promotor Expression_system: Escherichia Coli Expression_system_strain: Tg1 Expression_system_plasmid: Pmex602sakb Expression_system_gene: Taq Promotor
method	NMR, 20 Structures
related structures	by homologous chain: 1BUI
similarity	Belongs to the Staphylokinase family.
subcellular loc.	Secreted protein.
Gene	SAK (S. aureus)
function	Potent plasminogen activator that converts plasminogen into plasmin. It forms a 1. 1 complex with plasmin, which in turn activates other plasminogen molecules.
Gene Ontology	Chain Function Process Component A plasminogen activator activi...
Primary reference	Nuclear magnetic resonance solution structure of the plasminogen-activator protein staphylokinase., Ohlenschlager O, Ramachandran R, Guhrs KH, Schlott B, Brown LR, Biochemistry 1998 Jul 28;37(30):10635-42. PMID:9692953

Data retrieval

Asymmetric unit, PDB entry: [header only] [complete with coordinates] (755 Kb) [Save to disk] Biological Unit Coordinates (1ssn.pdb1.gz) 754 Kb CSU: Contacts of Structural Units for 1SSN Original NMR restraints for 1SSN from PDB Experimental data, such as chemical shifts, at BioMagResBank (BMRB) NMR Restraints Grid from BioMagResBank (BMRB) Retrieve 1SSN in mmCIF format [Save to disk]

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Structure-derived information

Dipole moment, from Dipole Server at Weizmann Institute Crystal Contacts, from CryCo at Weizmann Institute 3D motif for 1SSN, from MSDmotif at EBI Classification of representative domains in scop (Structural Classification of Proteins)     - Domain d1ssn__, region [Jmol] [rasmolscript] [script source] Fold representative 1ssn from FSSP and Dali (Families of Structurally Similar Proteins) Class (fold), Architecture (subfold), Topology, Homologous superfamily from CATH Summaries and structural analyses of PDB data files from PDBSum Identification of Protein Pockets & Cavities at CASTp

Sequence-derived information

View one-letter amino acid or nucleotide sequence for each chain: [1ssn_A]

Other resources with information on 1SSN

InterPro: IPR004093 NMR Ensemble (OLDERADO: core, domain and representative structure database) PDBREPORT (protein verification by WHAT_CHECK procedures) MMDB (Entrez's Structure Database)

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