1SE2	Toxin	date	Jul 20, 1995
title	Staphylococcal Enterotoxin C2, Monoclinic Form
authors	S.Swaminathan, M.Sax
compound		source
Molecule: Staphylococcal Enterotoxin C2 Chain: A Synonym: Sec2		Organism_scientific: Staphylococcus Aureus
symmetry	Space Group: P 1 21 1	R_factor	0.196
crystal cell	length a length b length c angle alpha angle beta angle gamma 43.430 69.920 42.220 90.00 90.10 90.00
method	X-Ray Diffraction	resolution	2.70 Å
related structures	by homologous chain: 1JWM, 1SEB
similarity	Belongs to the staphylococcal/streptococcal toxin family.[Stap_Strp_tox_C]
subcellular loc.	Secreted protein.
Gene	ENTC2 (S. aureus)
function	The illness characterized by high fever, hypotension, diarrhea, shock, and in some cases death. Staphylococcal enterotoxins cause the intoxication staphylococcal food poisoning syndrome.
Gene Ontology	Chain Function Process Component A pathogenesis extracellular region
Primary reference	Residues defining V beta specificity in staphylococcal enterotoxins., Swaminathan S, Furey W, Pletcher J, Sax M, Nat Struct Biol 1995 Aug;2(8):680-6. PMID:7552730

Data retrieval

Asymmetric unit, PDB entry: [header only] [complete with coordinates] (42 Kb) [Save to disk] Biological Unit Coordinates (1se2.pdb1.gz) 38 Kb CSU: Contacts of Structural Units for 1SE2 Likely Quarternary Molecular Structure file(s) for 1SE2 Retrieve 1SE2 in mmCIF format [Save to disk]

View 1SE2 in 3D

Proteopedia, because life has more than 2D. On Jmol, a nice Rasmol like molecule viewer. This is good for easiest viewing of basic structure. On FirstGlance, an excellent tool for a guided tour on the structure components, by E. Martz. On AstexViewer, from MSD-EBI (viewer documentation). On RasMol (Install RasMol freeware) Here's help on how to use RasMol.

Visual 3D analysis of 1SE2

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Structure-derived information

Dipole moment, from Dipole Server at Weizmann Institute Crystal Contacts, from CryCo at Weizmann Institute 3D motif for 1SE2, from MSDmotif at EBI Genome occurence of 1SE2's fold from GeneCensus Classification of representative domains in scop (Structural Classification of Proteins)     - Domain d1se2_1, region 1-120 [Jmol] [rasmolscript] [script source]     - Domain d1se2_2, region 121-239 [Jmol] [rasmolscript] [script source] Fold representative 1se2 from FSSP and Dali (Families of Structurally Similar Proteins) Class (fold), Architecture (subfold), Topology, Homologous superfamily from CATH Summaries and structural analyses of PDB data files from PDBSum Identification of Protein Pockets & Cavities at CASTp

Sequence-derived information

View one-letter amino acid or nucleotide sequence for each chain: [1se2_A]

Other resources with information on 1SE2

InterPro: IPR006123 , IPR006173 , IPR006177 , IPR006126 PDBREPORT (protein verification by WHAT_CHECK procedures) MMDB (Entrez's Structure Database)

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