1SAY	Oxidoreductase	date	Jun 05, 1998
title	L-Alanine Dehydrogenase Complexed With Pyruvate
authors	P.J.Baker, Y.Sawa, H.Shibata, S.E.Sedelnikova, D.W.Rice
compound		source
Molecule: L-Alanine Dehydrogenase Chain: A Ec: 1.4.1.1 Engineered: Yes Biological_unit: Homohexamer		Organism_scientific: Phormidium Lapideum Expression_system: Escherichia Coli Expression_system_strain: Mv1184 Expression_system_vector: Puc18 Expression_system_plasmid: Pnad1 Expression_system_gene: Aladh Other_details: Matsue Hot Springs
symmetry	Space Group: H 3 2	R_factor	0.18
crystal cell	length a length b length c angle alpha angle beta angle gamma 122.400 122.400 183.000 90.00 90.00 120.00
method	X-Ray Diffraction	resolution	2.1 Å
ligand	PYR	enzyme	1.4.1.1. Oxidoreductase E.C.1.4.1.1 BRENDA
note	1SAY is a representative structure
Gene Ontology	Chain Function Process Component A alanine dehydrogenase activi... oxidoreductase activity electron transport
Primary reference	Analysis of the structure and substrate binding of Phormidium lapideum alanine dehydrogenase., Baker PJ, Sawa Y, Shibata H, Sedelnikova SE, Rice DW, Nat Struct Biol 1998 Jul;5(7):561-7. PMID:9665169

Data retrieval

Asymmetric unit, PDB entry: [header only] [complete with coordinates] (69 Kb) [Save to disk] Biological Unit Coordinates (1say.pdb1.gz) 325 Kb CSU: Contacts of Structural Units for 1SAY Likely Quarternary Molecular Structure file(s) for 1SAY Retrieve 1SAY in mmCIF format [Save to disk]

View 1SAY in 3D

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Visual 3D analysis of 1SAY

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Structure-derived information

Dipole moment, from Dipole Server at Weizmann Institute Crystal Contacts, from CryCo at Weizmann Institute 3D motif for 1SAY, from MSDmotif at EBI Classification of representative domains in scop (Structural Classification of Proteins)     - Domain d1saya2, region A:1-135,A:304-361 [Jmol] [rasmolscript] [script source]     - Domain d1saya1, region A:136-303 [Jmol] [rasmolscript] [script source] Fold representative 1say from FSSP and Dali (Families of Structurally Similar Proteins) Class (fold), Architecture (subfold), Topology, Homologous superfamily from CATH Summaries and structural analyses of PDB data files from PDBSum Identification of Protein Pockets & Cavities at CASTp

Sequence-derived information

View one-letter amino acid or nucleotide sequence for each chain: [1say_A]

Other resources with information on 1SAY

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