1RVX	Viral Protein	date	Dec 15, 2003
title	1934 H1 Hemagglutinin In Complex With Lsta
authors	S.J.Gamblin, L.F.Haire, R.J.Russell, D.J.Stevens, B.Xiao, Y.Ha, N.Vasisht, D.A.Steinhauer, R.S.Daniels, A.Elliot, D.C.Wiley, J.J.Skehel
compound		source
Molecule: Hemagglutinin Chain: A, C, E, G, I, K Other_details: Hemagglutinin Ha1 Chain		Organism_scientific: Influenza A Virus (Apuerto Rico834(H1n1)); Organism_taxid: 211044 Strain: A-Puerto Rico-8-34 Other_details: Bromelain Digestion
Molecule: Hemagglutinin Chain: B, D, F, H, J, L Other_details: Hemagglutinin Ha2 Chain		Organism_scientific: Influenza A Virus (Apuerto Rico834(H1n1)); Organism_taxid: 211044 Strain: A-Puerto Rico-8-34 Other_details: Bromelain Digestion
symmetry	Space Group: C 1 2 1	R_factor 0.227 R_Free 0.260
crystal cell	length a length b length c angle alpha angle beta angle gamma 227.878 131.344 174.708 90.00 110.09 90.00
method	X-Ray Diffraction	resolution	2 Å
ligand	GAL, NAG, SIA	enzyme
note	1RVX is a representative structure
related structures	by homologous chain: 1JSM, 1RVZ
Gene Ontology	Chain Function Process Component F, A, J, K, E, B, H, C, D, I, G, L host cell surface receptor b... viral envelope fusion with h... Golgi membrane endoplasmic reticulum membra... plasma membrane membrane integral to membrane virion viral envelope host cell plasma membrane endocytic vesicle membrane virion membrane
Primary reference	The structure and receptor binding properties of the 1918 influenza hemagglutinin., Gamblin SJ, Haire LF, Russell RJ, Stevens DJ, Xiao B, Ha Y, Vasisht N, Steinhauer DA, Daniels RS, Elliot A, Wiley DC, Skehel JJ, Science 2004 Mar 19;303(5665):1838-42. Epub 2004 Feb 5. PMID:14764886

Data retrieval

Asymmetric unit, PDB entry: [header only] [complete with coordinates] (533 Kb) [Save to disk] Biological Unit Coordinates (1rvx.pdb1.gz) 266 Kb Biological Unit Coordinates (1rvx.pdb2.gz) 265 Kb CSU: Contacts of Structural Units for 1RVX Likely Quarternary Molecular Structure file(s) for 1RVX Retrieve 1RVX in mmCIF format [Save to disk]

View 1RVX in 3D

Proteopedia, because life has more than 2D. On Jmol, a nice Rasmol like molecule viewer. This is good for easiest viewing of basic structure. On FirstGlance, an excellent tool for a guided tour on the structure components, by E. Martz. On AstexViewer, from MSD-EBI (viewer documentation). On RasMol (Install RasMol freeware) Here's help on how to use RasMol.

Visual 3D analysis of 1RVX

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Structure-derived information

Dipole moment, from Dipole Server at Weizmann Institute Crystal Contacts, from CryCo at Weizmann Institute 3D motif for 1RVX, from MSDmotif at EBI Classification of representative domains in scop (Structural Classification of Proteins)     - Domain d1rvxa_, region A [Jmol] [rasmolscript] [script source]     - Domain d1rvxb_, region B [Jmol] [rasmolscript] [script source]     - Domain d1rvxc_, region C [Jmol] [rasmolscript] [script source]     - Domain d1rvxd_, region D [Jmol] [rasmolscript] [script source]     - Domain d1rvxe_, region E [Jmol] [rasmolscript] [script source]     - Domain d1rvxf_, region F [Jmol] [rasmolscript] [script source]     - Domain d1rvxg_, region G [Jmol] [rasmolscript] [script source]     - Domain d1rvxh_, region H [Jmol] [rasmolscript] [script source]     - Domain d1rvxi_, region I [Jmol] [rasmolscript] [script source]     - Domain d1rvxj_, region J [Jmol] [rasmolscript] [script source]     - Domain d1rvxk_, region K [Jmol] [rasmolscript] [script source]     - Domain d1rvxl_, region L [Jmol] [rasmolscript] [script source] Fold representative 1rvx from FSSP and Dali (Families of Structurally Similar Proteins) Class (fold), Architecture (subfold), Topology, Homologous superfamily from CATH Summaries and structural analyses of PDB data files from PDBSum Identification of Protein Pockets & Cavities at CASTp

Sequence-derived information

View one-letter amino acid or nucleotide sequence for each chain: [1rvx_A] [1rvx_C] [1rvx_J] [1rvx_I] [1rvx_G] [1rvx_H] [1rvx_B] [1rvx_D] [1rvx_L] [1rvx_F] [1rvx_E] [1rvx_K]

Other resources with information on 1RVX

MMDB (Entrez's Structure Database)

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