1OUV | Hydrolase | date | Mar 25, 2003 ![]() |
||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
title | Helicobacter Cysteine Rich Protein C (Hcpc) | ||||||||||||||
authors | P.R.Mittl, L.Luethy | ||||||||||||||
compound | source | ||||||||||||||
Molecule: Conserved Hypothetical Secreted Protein Chain: A Synonym: Helicobacter Cysteine Rich Protein C, Hcpc Engineered: Yes |
Organism_scientific: Helicobacter Pylori Organism_common: Bacteria Strain: 26695 Gene: Hp1098 Expression_system: Escherichia Coli Expression_system_common: Bacteria Expression_system_strain: Bl21(De3) Expression_system_vector_type: Plasmid Expression_system_vector: T7 Expression_system_plasmid: Ptft74 | ||||||||||||||
symmetry | Space Group: C 1 2 1 | R_factor | 0.202 | ||||||||||||
crystal cell |
| ||||||||||||||
method | X-Ray Diffraction | resolution | 2.00 Å | ||||||||||||
note | 1OUV is a representative structure | ||||||||||||||
similarity | Contains 7 tpr repeats. Belongs to the hcp beta-lactamase family.[TPR_1] | ||||||||||||||
catalytic activ. | A beta-lactam + h(2)o = a substituted beta- amino acid. | ||||||||||||||
subcellular loc. | Secreted protein (potential). | ||||||||||||||
gene | hcpC (H. pylori) | ||||||||||||||
function | May hydrolyze 6-aminopenicillinic acid and 7- aminocephalosporanic acid (aca) derivatives (by similarity). | ||||||||||||||
Gene Ontology |
| ||||||||||||||
Primary reference | The Crystal Structure of Helicobacter Cysteine-rich Protein C at 2.0A Resolution: Similar Peptide-binding Sites in TPR and SEL1-like Repeat Proteins., Luthy L, Grutter MG, Mittl PR, J Mol Biol 2004 Jul 16;340(4):829-41. PMID:15223324 |
Data retrieval |
![]() |
View 1OUV in 3D |
|
Visual 3D analysis of 1OUV |
|
Structure-derived information |
- Domain d1ouva_, region A [Jmol] [rasmolscript] [script source] |
Sequence-derived information |
Other resources with information on 1OUV |
Movements, Movies and Images |