1OMI	Transcription	date	Feb 25, 2003
title	Crystal Structure Of Prfa,The Transcriptional Regulator In Listeria Monocytogenes
authors	R.Thirumuruhan, K.Rajashankar, A.A.Fedorov, T.Dodatko, M.R.Chance, P.Cossart, S.C.Almo, S.K.Burley, New York Structural Genomix Research Consortium (Nysgxrc)
compound		source
Molecule: Listeriolysin Regulatory Protein Chain: A, B Engineered: Yes		Organism_scientific: Listeria Monocytogenes Organism_common: Bacteria Gene: Prfa Or Lmo0200 Expression_system: Escherichia Coli Expression_system_common: Bacteria
symmetry	Space Group: P 21 21 21	R_factor	0.244
crystal cell	length a length b length c angle alpha angle beta angle gamma 69.430 72.091 114.335 90.00 90.00 90.00
method	X-Ray Diffraction	resolution	2.80 Å
ligand	GOL	enzyme
related structures	by homologous chain: 2BEO
similarity	Contains1 hth crp-type dna-binding domain.
Genes	LMO0200, PRFA (L. monocytogenes)
function	Positively regulates expression of listeriolysin, of 1- phosphadidylinositol phosphodiesterase (pi-plc) and other virulence factors.
Gene Ontology	Chain Function Process Component A, B DNA binding transcription regulation of transcription,... pathogenesis regulation of transcription

Data retrieval

Asymmetric unit, PDB entry: [header only] [complete with coordinates] (80 Kb) [Save to disk] Biological Unit Coordinates (1omi.pdb1.gz) 39 Kb Biological Unit Coordinates (1omi.pdb2.gz) 40 Kb CSU: Contacts of Structural Units for 1OMI Likely Quarternary Molecular Structure file(s) for 1OMI Structure Factors (237 Kb) Retrieve 1OMI in mmCIF format [Save to disk]

View 1OMI in 3D

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Structure-derived information

Electron Density related parameters from EDS Electron Density Server, at Upsala Dipole moment, from Dipole Server at Weizmann Institute Crystal Contacts, from CryCo at Weizmann Institute 3D motif for 1OMI, from MSDmotif at EBI Classification of representative domains in scop (Structural Classification of Proteins)     - Domain d1omia1, region A:1005-1137 [Jmol] [rasmolscript] [script source]     - Domain d1omia2, region A:1138-1237 [Jmol] [rasmolscript] [script source]     - Domain d1omib1, region B:2005-2137 [Jmol] [rasmolscript] [script source]     - Domain d1omib2, region B:2138-2237 [Jmol] [rasmolscript] [script source] Fold representative 1omi from FSSP and Dali (Families of Structurally Similar Proteins) Class (fold), Architecture (subfold), Topology, Homologous superfamily from CATH Summaries and structural analyses of PDB data files from PDBSum Identification of Protein Pockets & Cavities at CASTp

Sequence-derived information

View one-letter amino acid or nucleotide sequence for each chain: [1omi_A] [1omi_B]

Other resources with information on 1OMI

InterPro: IPR012318 , IPR000595 , IPR011991 , IPR001808 PDBREPORT (protein verification by WHAT_CHECK procedures) MMDB (Entrez's Structure Database)

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