1HX5 | Chaperone | date | Jan 11, 2001 ![]() |
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title | Crystal Structure Of M. Tuberculosis Chaperonin-10 | ||||||||||||||
authors | B.Taneja, S.C.Mande, Tb Structural Genomics Consortium (Tbsgc) | ||||||||||||||
compound | source | ||||||||||||||
Molecule: 10 Kda Chaperonin Chain: A, B, C, D, E, F, G Synonym: Protein Cpn10 Engineered: Yes |
Organism_scientific: Mycobacterium Tuberculosis Organism_common: Bacteria Gene: Rv3418c Expression_system: Escherichia Coli Expression_system_common: Bacteria Expression_system_strain: Jm109 Expression_system_vector_type: Plasmid Expression_system_plasmid: Pmal-C | ||||||||||||||
symmetry | Space Group: C 2 2 21 | R_factor | 0.202 | ||||||||||||
crystal cell |
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method | X-Ray Diffraction | resolution | 3.50 Å | ||||||||||||
similarity | Belongs to the groes chaperonin family.[Cpn10] | ||||||||||||||
subunit | Heptamer of 7 subunits arranged in a ring (by similarity). | ||||||||||||||
subcellular loc. | Cytoplasm (by similarity). | ||||||||||||||
gene | MT3527 (M. tuberculosis) | ||||||||||||||
function | Binds to cpn60 in the presence of mg-atp and suppresses the atpase activity of the latter. | ||||||||||||||
Gene Ontology |
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Primary reference | Molecular topology of polycyclic aromatic carcinogens determines DNA adduct conformation: a link to tumorigenic activity., Lin CH, Huang X, Kolbanovskii A, Hingerty BE, Amin S, Broyde S, Geacintov NE, Patel DJ, J Mol Biol 2001 Mar 9;306(5):1059-80. PMID:11237618 |
Data retrieval |
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View 1HX5 in 3D |
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Visual 3D analysis of 1HX5 |
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Structure-derived information |
- Domain d1hx5a_, region A [Jmol] [rasmolscript] [script source] - Domain d1hx5b_, region B [Jmol] [rasmolscript] [script source] - Domain d1hx5c_, region C [Jmol] [rasmolscript] [script source] - Domain d1hx5d_, region D [Jmol] [rasmolscript] [script source] - Domain d1hx5e_, region E [Jmol] [rasmolscript] [script source] - Domain d1hx5f_, region F [Jmol] [rasmolscript] [script source] - Domain d1hx5g_, region G [Jmol] [rasmolscript] [script source] |
Sequence-derived information |
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