1HUF	Hydrolase	date	Jan 04, 2001
title	Crystal Structure Of The N-Terminal Domain Of The Tyrosine Phosphatase Yoph From Yersinia Pestis.
authors	A.G.Evdokimov, D.S.Waugh
compound		source
Molecule: Tyrosine Phosphatase Yoph Chain: A Fragment: N-Terminal Domain Synonym: Virulence Protein Ec: 3.1.3.48 Engineered: Yes		Organism_scientific: Yersinia Pestis Organism_common: Bacteria Gene: Yoph Expression_system: Escherichia Coli Expression_system_common: Bacteria Expression_system_strain: Bl21(De3)-Ril Expression_system_vector_type: Pdonr201 Expression_system_plasmid: Pkm904
symmetry	Space Group: C 2 2 21	R_factor	0.189
crystal cell	length a length b length c angle alpha angle beta angle gamma 48.063 120.651 49.036 90.00 90.00 90.00
method	X-Ray Diffraction	resolution	2.00 Å
ligand		enzyme	Hydrolase E.C.3.1.3.48 BRENDA
note	1HUF is a representative structure
related structures	by homologous chain: 1K46
Gene	YOPH (Y. pestis)
Gene Ontology	Chain Function Process Component A protein tyrosine phosphatase... hydrolase activity phosphoric monoester hydrola... protein amino acid dephospho... pathogenesis dephosphorylation
Primary reference	Structure of the N-terminal domain of Yersinia pestis YopH at 2.0 A resolution., Evdokimov AG, Tropea JE, Routzahn KM, Copeland TD, Waugh DS, Acta Crystallogr D Biol Crystallogr 2001 Jun;57(Pt 6):793-9. PMID:11375498

Data retrieval

Asymmetric unit, PDB entry: [header only] [complete with coordinates] (25 Kb) [Save to disk] Biological Unit Coordinates (1huf.pdb1.gz) 21 Kb CSU: Contacts of Structural Units for 1HUF Likely Quarternary Molecular Structure file(s) for 1HUF Structure Factors (163 Kb) Retrieve 1HUF in mmCIF format [Save to disk]

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Structure-derived information

Electron Density related parameters from EDS Electron Density Server, at Upsala Dipole moment, from Dipole Server at Weizmann Institute Crystal Contacts, from CryCo at Weizmann Institute 3D motif for 1HUF, from MSDmotif at EBI Classification of representative domains in scop (Structural Classification of Proteins)     - Domain d1hufa_, region A [Jmol] [rasmolscript] [script source] Fold representative 1huf from FSSP and Dali (Families of Structurally Similar Proteins)

Sequence-derived information

View one-letter amino acid or nucleotide sequence for each chain: [1huf_A]

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