1GOZ	Enterotoxin	date	Oct 29, 2001
title	Structural Basis For The Altered T-Cell Receptor Binding Specificty In A Superantigenic Staphylococcus Aureus Enterotoxin-B Mutant
authors	M.D.Baker, A.C.Papageorgiou, K.R.Acharya
compound		source
Molecule: Enterotoxin Type B Chain: A, B Engineered: Yes Mutation: Yes		Organism_scientific: Staphylococcus Aureus Expression_system: Escherichia Coli
symmetry	Space Group: P 21 21 21	R_factor	0.227
crystal cell	length a length b length c angle alpha angle beta angle gamma 39.545 98.555 126.469 90.00 90.00 90.00
method	X-Ray Diffraction	resolution	2.00 Å
related structures	by homologous chain: 1D5Z, 1I4P
similarity	Belongs to the staphylococcal/streptococcal toxin family.[Stap_Strp_tox_C]
subcellular loc.	Secreted protein.
Gene	ENTB (S. aureus)
function	The illness characterized by high fever, hypotension, diarrhea, shock, and in some cases death. Staphylococcal enterotoxins cause the intoxication staphylococcal food poisoning syndrome.
Gene Ontology	Chain Function Process Component A, B pathogenesis extracellular region
Primary reference	Structural and functional role of threonine 112 in a superantigen Staphylococcus aureus enterotoxin B., Baker MD, Papageorgiou AC, Titball RW, Miller J, White S, Lingard B, Lee JJ, Cavanagh D, Kehoe MA, Robinson JH, Acharya KR, J Biol Chem 2002 Jan 25;277(4):2756-62. PMID:11704673

Data retrieval

Asymmetric unit, PDB entry: [header only] [complete with coordinates] (84 Kb) [Save to disk] Biological Unit Coordinates (1goz.pdb1.gz) 43 Kb Biological Unit Coordinates (1goz.pdb2.gz) 39 Kb CSU: Contacts of Structural Units for 1GOZ Likely Quarternary Molecular Structure file(s) for 1GOZ Retrieve 1GOZ in mmCIF format [Save to disk]

View 1GOZ in 3D

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Visual 3D analysis of 1GOZ

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Structure-derived information

Dipole moment, from Dipole Server at Weizmann Institute Crystal Contacts, from CryCo at Weizmann Institute 3D motif for 1GOZ, from MSDmotif at EBI Classification of representative domains in scop (Structural Classification of Proteins)     - Domain d1goza1, region A:1001-1121 [Jmol] [rasmolscript] [script source]     - Domain d1goza2, region A:1122-1238 [Jmol] [rasmolscript] [script source]     - Domain d1gozb1, region B:2001-2121 [Jmol] [rasmolscript] [script source]     - Domain d1gozb2, region B:2122-2238 [Jmol] [rasmolscript] [script source] Fold representative 1goz from FSSP and Dali (Families of Structurally Similar Proteins) Class (fold), Architecture (subfold), Topology, Homologous superfamily from CATH Summaries and structural analyses of PDB data files from PDBSum Identification of Protein Pockets & Cavities at CASTp

Sequence-derived information

View one-letter amino acid or nucleotide sequence for each chain: [1goz_A] [1goz_B]

Other resources with information on 1GOZ

InterPro: IPR006123 , IPR006173 , IPR006177 , IPR006126 PDBREPORT (protein verification by WHAT_CHECK procedures) MMDB (Entrez's Structure Database)

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