1EEI Toxin date Jan 31, 2000
title Cholera Toxin B-Pentamer Complexed With Metanitrophenyl- Alpha-D-Galactose
authors E.A.Merritt, W.G.J.Hol
compound source
Molecule: Cholera Toxin B
Chain: D, E, F, G, H
Engineered: Yes
Other_details: Receptor Binding Site On Each Monomer Occupied By Metanitrophenyl-Alpha-D-Galactoside
 Organism_scientific: Vibrio Cholerae
Strain: Ogawa 41 (Classical Biotype)
Expression_system: Escherichia Coli
Expression_system_common: Bacteria
symmetry Space Group: P 21 21 21
R_factor 0.200
crystal
cell
length a length b length c angle alpha angle beta angle gamma
68.900 69.550 130.660 90.00 90.00 90.00
method X-Ray Diffractionresolution 2.00 Å
ligand GAA enzyme
Gene
Ontology
ChainFunctionProcessComponent
H, F, D, G, E
  • pathogenesis
  • extracellular region
    • Primary referenceExploration of the GM1 receptor-binding site of heat-labile enterotoxin and cholera toxin by phenyl-ring-containing galactose derivatives., Fan E, Merritt EA, Zhang Z, Pickens JC, Roach C, Ahn M, Hol WG, Acta Crystallogr D Biol Crystallogr 2001 Feb;57(Pt 2):201-12. PMID:11173465
    Data retrieval
  • Asymmetric unit, PDB entry: [header only] [complete with coordinates] (109 Kb) [Save to disk]
  • Biological Unit Coordinates (1eei.pdb1.gz) 94 Kb
  • CSU: Contacts of Structural Units for 1EEI
  • Likely Quarternary Molecular Structure file(s) for 1EEI
  • Structure Factors (318 Kb)
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  • Classification of representative domains in scop (Structural Classification of Proteins)
        - Domain d1eeid_, region D [Jmol] [rasmolscript] [script source]
        - Domain d1eeie_, region E [Jmol] [rasmolscript] [script source]
        - Domain d1eeif_, region F [Jmol] [rasmolscript] [script source]
        - Domain d1eeig_, region G [Jmol] [rasmolscript] [script source]
        - Domain d1eeih_, region H [Jmol] [rasmolscript] [script source]
  • Fold representative 1eei from FSSP and Dali (Families of Structurally Similar Proteins)
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