1CQV	Toxin	date	Aug 11, 1999
title	Crystal Structure Of Staphylococcal Enterotoxin C2 At 100k Crystallized At Ph 5.0
authors	D.Kumaran, S.Swaminathan
compound		source
Molecule: Protein (Staphylococcal Enterotoxin C2) Chain: A Synonym: Sec2		Organism_scientific: Staphylococcus Aureus Organism_common: Bacteria
symmetry	Space Group: P 43 21 2	R_factor	0.208
crystal cell	length a length b length c angle alpha angle beta angle gamma 42.683 42.683 289.149 90.00 90.00 90.00
method	X-Ray Diffraction	resolution	2.06 Å
ligand	ZN	enzyme
related structures	by homologous chain: 1D5M, 1I4R
similarity	Belongs to the staphylococcal/streptococcal toxin family.[Stap_Strp_tox_C]
subcellular loc.	Secreted protein.
Gene	ENTC2 (S. aureus)
function	The illness characterized by high fever, hypotension, diarrhea, shock, and in some cases death. Staphylococcal enterotoxins cause the intoxication staphylococcal food poisoning syndrome.
Gene Ontology	Chain Function Process Component A zinc ion binding metal ion binding pathogenesis extracellular region
Primary reference	Structure of staphylococcal enterotoxin C2 at various pH levels., Kumaran D, Eswaramoorthy S, Furey W, Sax M, Swaminathan S, Acta Crystallogr D Biol Crystallogr 2001 Sep;57(Pt 9):1270-5. PMID:11526318

Data retrieval

Asymmetric unit, PDB entry: [header only] [complete with coordinates] (45 Kb) [Save to disk] Biological Unit Coordinates (1cqv.pdb1.gz) 41 Kb CSU: Contacts of Structural Units for 1CQV Likely Quarternary Molecular Structure file(s) for 1CQV Structure Factors (165 Kb) Retrieve 1CQV in mmCIF format [Save to disk]

View 1CQV in 3D

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Visual 3D analysis of 1CQV

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Structure-derived information

Electron Density related parameters from EDS Electron Density Server, at Upsala Dipole moment, from Dipole Server at Weizmann Institute Crystal Contacts, from CryCo at Weizmann Institute 3D motif for 1CQV, from MSDmotif at EBI Classification of representative domains in scop (Structural Classification of Proteins)     - Domain d1cqva1, region A:1-120 [Jmol] [rasmolscript] [script source]     - Domain d1cqva2, region A:121-239 [Jmol] [rasmolscript] [script source] Fold representative 1cqv from FSSP and Dali (Families of Structurally Similar Proteins) Class (fold), Architecture (subfold), Topology, Homologous superfamily from CATH Summaries and structural analyses of PDB data files from PDBSum Identification of Protein Pockets & Cavities at CASTp

Sequence-derived information

View one-letter amino acid or nucleotide sequence for each chain: [1cqv_A]

Other resources with information on 1CQV

InterPro: IPR006123 , IPR006173 , IPR006177 , IPR006126 PDBREPORT (protein verification by WHAT_CHECK procedures) MMDB (Entrez's Structure Database)

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