1CKR | Chaperone | date | Apr 22, 1999 ![]() |
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title | High Resolution Solution Structure Of The Heat Shock Cognate-70 Kd Substrate Binding Domain Obtained By Multidimensional Nmr Techniques | ||||||||||
authors | R.C.Morshauser, W.Hu, H.Wang, Y.Pang, G.C.Flynn, E.R.P.Zuiderweg | ||||||||||
compound | source | ||||||||||
Molecule: Heat Shock Substrate Binding Domain Of Hsc-70 Chain: A Fragment: Substrate Binding Domain Engineered: Yes |
Organism_scientific: Rattus Norvegicus Organism_common: Rat Expression_system: Escherichia Coli Expression_system_strain: Jm109(De3) | ||||||||||
method | NMR, 20 Structures | ||||||||||
similarity | Belongs to the heat shock protein 70 family.[HSP70] | ||||||||||
subunit | Interacts with pacrg (by similarity). | ||||||||||
induction | Constitutively synthesized. | ||||||||||
subcellular loc. | Translocates rapidly from the cytoplasm to the nuclei, and especially to the nucleoli, upon heat shock (by similarity). | ||||||||||
genes | Hsc73, Hspa8 (R. norvegicus) | ||||||||||
function | Chaperone. | ||||||||||
Gene Ontology |
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Primary reference | High-resolution solution structure of the 18 kDa substrate-binding domain of the mammalian chaperone protein Hsc70., Morshauser RC, Hu W, Wang H, Pang Y, Flynn GC, Zuiderweg ER, J Mol Biol 1999 Jun 25;289(5):1387-403. PMID:10373374 |
Data retrieval |
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Visual 3D analysis of 1CKR |
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Structure-derived information |
- Domain d1ckra_, region A [Jmol] [rasmolscript] [script source] |
Sequence-derived information |
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