1AW7 | Toxin | date | Oct 11, 1997 ![]() ![]() |
||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
title | Q136a Mutant Of Toxic Shock Syndrome Toxin-1 From S. Aureus | ||||||||||||||
authors | C.A.Earhart, D.T.Mitchell, D.L.Murray, D.M.Pinheiro, M.Matsumura, P.M.Schlievert, D.H.Ohlendorf | ||||||||||||||
compound | source | ||||||||||||||
Molecule: Toxic Shock Syndrome Toxin-1 Chain: A, B, C, D Synonym: Tsst-1 Engineered: Yes Mutation: Yes |
Organism_scientific: Staphylococcus Aureus | ||||||||||||||
symmetry | Space Group: P 1 | R_factor | 0.176 | ||||||||||||
crystal cell |
| ||||||||||||||
method | X-Ray Diffraction | resolution | 1.95 Å | ||||||||||||
related structures | by homologous chain: 1TS3, 3TSS | ||||||||||||||
similarity | Belongs to the staphylococcal/streptococcal toxin family.[Stap_Strp_toxin] | ||||||||||||||
subcellular loc. | Secreted protein. | ||||||||||||||
Gene | TST (S. aureus) | ||||||||||||||
function | Responsible for the symptoms of toxic shock syndrome. | ||||||||||||||
Gene Ontology |
| ||||||||||||||
Primary reference | Structures of five mutants of toxic shock syndrome toxin-1 with reduced biological activity., Earhart CA, Mitchell DT, Murray DL, Pinheiro DM, Matsumura M, Schlievert PM, Ohlendorf DH, Biochemistry 1998 May 19;37(20):7194-202. PMID:9585531 |
Data retrieval |
![]() |
View 1AW7 in 3D |
![]() |
Visual 3D analysis of 1AW7 |
|
Structure-derived information |
- Domain d1aw7a1, region A:1-93 [Jmol] [rasmolscript] [script source] - Domain d1aw7a2, region A:94-194 [Jmol] [rasmolscript] [script source] - Domain d1aw7b1, region B:201-293 [Jmol] [rasmolscript] [script source] - Domain d1aw7b2, region B:294-394 [Jmol] [rasmolscript] [script source] - Domain d1aw7c1, region C:401-493 [Jmol] [rasmolscript] [script source] - Domain d1aw7c2, region C:494-594 [Jmol] [rasmolscript] [script source] - Domain d1aw7d1, region D:601-693 [Jmol] [rasmolscript] [script source] - Domain d1aw7d2, region D:694-794 [Jmol] [rasmolscript] [script source] |
Sequence-derived information |
Other resources with information on 1AW7 |
Movements, Movies and Images |