EbolaVCR: Computational resources for designing drugs and vaccines against EBOLA virus

Welcome to Home page of EbolaVCR

Ebola Virus Computational Resources (EbolaVCR) is the in silico resources developed to facilitate scientific community fighting against deadly virus EBOLA. This server enlists possible vaccine candidates, therapeutic siRNAs and other related resources.
Reference: Dhanda et. al. (2016) A web-based resource for designing therapeutics against Ebola Virus. Sci Rep. 6:24782.

Detail of Antigen (GP) in Strain (Sudan Ebola Virus (SUDV))

This page provides comprehensive information about antigen GP in strain Sudan Ebola Virus (SUDV) required for designing epitope-based vaccine.

Important Information Detail (Number)
Name of AntigenGP
Name of StrainSudan Ebola Virus (SUDV)
Present in number of strains5
Gene IDgi_55770812
Protein IDYP_138523.1
Mapping of epitopesVisualize
Sequence conservationVisualize Alignment
Phylogenetic treeView tree
Number of organims with epitope mapped4
Number of epitope mapped422
Number of epitope mapped uniq417
Number of 9mer668
Number of 9mer uniq668
Number of 9mer uniq with no human ref668
Number of 9mer (not present in 1000 genome)668
Number of B cell epitope40
Number of MHC class II binders (Propred)100
Number of MHC class I binders (Propred1)449
Number of MHC class I binders (nHLApred)84
Number of CTL epitope (CTLpred)84
Number of IFN inducer (IFNepitope)231
Number of Th1 inducer (IFNepitope + Propred)34
Number of IL4 inducer (IL4pred)420
Number of Th2 inducer (IL4pred + Propred)57