EbolaVCR: Computational resources for designing drugs and vaccines against EBOLA virus

Welcome to Home page of EbolaVCR

Ebola Virus Computational Resources (EbolaVCR) is the in silico resources developed to facilitate scientific community fighting against deadly virus EBOLA. This server enlists possible vaccine candidates, therapeutic siRNAs and other related resources.
Reference: Dhanda et. al. (2016) A web-based resource for designing therapeutics against Ebola Virus. Sci Rep. 6:24782.

Detail of Antigen (VP35) in Strain (Reston Ebola Virus (RESTV))

This page provides comprehensive information about antigen VP35 in strain Reston Ebola Virus (RESTV) required for designing epitope-based vaccine.

Important Information Detail (Number)
Name of AntigenVP35
Name of StrainReston Ebola Virus (RESTV)
Present in number of strains5
Gene IDgi_22789224
Protein IDNP_690581.1
Mapping of epitopesVisualize
Sequence conservationVisualize Alignment
Phylogenetic treeView tree
Number of organims with epitope mapped3
Number of epitope mapped11
Number of epitope mapped uniq9
Number of 9mer321
Number of 9mer uniq321
Number of 9mer uniq with no human ref321
Number of 9mer (not present in 1000 genome)321
Number of B cell epitope48
Number of MHC class II binders (Propred)46
Number of MHC class I binders (Propred1)214
Number of MHC class I binders (nHLApred)44
Number of CTL epitope (CTLpred)44
Number of IFN inducer (IFNepitope)109
Number of Th1 inducer (IFNepitope + Propred)12
Number of IL4 inducer (IL4pred)229
Number of Th2 inducer (IL4pred + Propred)32