EbolaVCR: Computational resources for designing drugs and vaccines against EBOLA virus

Welcome to Home page of EbolaVCR

Ebola Virus Computational Resources (EbolaVCR) is the in silico resources developed to facilitate scientific community fighting against deadly virus EBOLA. This server enlists possible vaccine candidates, therapeutic siRNAs and other related resources.
Reference: Dhanda et. al. (2016) A web-based resource for designing therapeutics against Ebola Virus. Sci Rep. 6:24782.

Detail of Antigen (NP) in Strain (Reston Ebola Virus (RESTV))

This page provides comprehensive information about antigen NP in strain Reston Ebola Virus (RESTV) required for designing epitope-based vaccine.

Important Information Detail (Number)
Name of AntigenNP
Name of StrainReston Ebola Virus (RESTV)
Present in number of strains5
Gene IDgi_22789223
Protein IDNP_690580.1
Mapping of epitopesVisualize
Sequence conservationVisualize Alignment
Phylogenetic treeView tree
Number of organims with epitope mapped6
Number of epitope mapped7
Number of epitope mapped uniq6
Number of 9mer731
Number of 9mer uniq731
Number of 9mer uniq with no human ref731
Number of 9mer (not present in 1000 genome)731
Number of B cell epitope50
Number of MHC class II binders (Propred)99
Number of MHC class I binders (Propred1)464
Number of MHC class I binders (nHLApred)108
Number of CTL epitope (CTLpred)108
Number of IFN inducer (IFNepitope)283
Number of Th1 inducer (IFNepitope + Propred)28
Number of IL4 inducer (IL4pred)501
Number of Th2 inducer (IL4pred + Propred)65