EbolaVCR: Computational resources for designing drugs and vaccines against EBOLA virus

Welcome to Home page of EbolaVCR

Ebola Virus Computational Resources (EbolaVCR) is the in silico resources developed to facilitate scientific community fighting against deadly virus EBOLA. This server enlists possible vaccine candidates, therapeutic siRNAs and other related resources.
Reference: Dhanda et. al. (2016) A web-based resource for designing therapeutics against Ebola Virus. Sci Rep. 6:24782.

Detail of Antigen (GP) in Strain (Reston Ebola Virus (RESTV))

This page provides comprehensive information about antigen GP in strain Reston Ebola Virus (RESTV) required for designing epitope-based vaccine.

Important Information Detail (Number)
Name of AntigenGP
Name of StrainReston Ebola Virus (RESTV)
Present in number of strains5
Gene IDgi_22789230
Protein IDNP_690583.1
Mapping of epitopesVisualize
Sequence conservationVisualize Alignment
Phylogenetic treeView tree
Number of organims with epitope mapped4
Number of epitope mapped15
Number of epitope mapped uniq7
Number of 9mer669
Number of 9mer uniq669
Number of 9mer uniq with no human ref669
Number of 9mer (not present in 1000 genome)669
Number of B cell epitope30
Number of MHC class II binders (Propred)103
Number of MHC class I binders (Propred1)429
Number of MHC class I binders (nHLApred)82
Number of CTL epitope (CTLpred)82
Number of IFN inducer (IFNepitope)183
Number of Th1 inducer (IFNepitope + Propred)31
Number of IL4 inducer (IL4pred)440
Number of Th2 inducer (IL4pred + Propred)68