Please click on the ID to see detailed information about each entry.
The total number entries retrieved from this search are| ID | Sequence | Name | Nature of peptide or cargo | Assay | Tissue permeability | Tissue Sample | PUBMED ID |
|---|---|---|---|---|---|---|---|
| 1089 | (GSGAGA)n | Silk fibroin peptide (3,000 Da) | Anti-inflammatory | Histochemical analysis | Significant permeability of the silk peptide can be seen in histochemical images | Ear of mice | 22189681 |
| 1090 | (GSGAGA)n | Silk fibroin peptide (3,000 Da) | Anti-inflammatory | RT-PCR, Western blotting | Significant decrease in translation of COX-2, IL-6 and IL-1β in presence of silk peptide +Tat-SOD can be seen in western blot images | HaCaT keratinocytes | 22189681 |
| 1254 | VTHRLAGLLSRSGGM VKSNFVPTNVGSKAF | CGRP receptor antagonist CGRP(8-37) | Regulation of blood flow, modulation of inflammation, and tissue remodelling | Photographed both hind paws using a micro-computer imaging device(MCID)-assessed analysis system. Immunostaining. Mann-Whitney U-test. | Effect of the CGRP-receptor antagonist CGRP(8-37)(~24.5 mm2) on the necrotic area in UV-damaged skin of the rat hindpaw compared to solvent applications(~36.5 mm2). | The dorsum of both hind paws were irradiated of male Sprague-Dawley (SD) rats. | 8584255 |
| 1255 | VTHRLAGLLSRSGGM VKSNFVPTNVGSKAF | CGRP receptor antagonist CGRP(8-37) | Regulation of blood flow, modulation of inflammation, and tissue remodelling | Photographed both hind paws using a micro-computer imaging device(MCID)-assessed analysis system. Immunostaining. Mann-Whitney U-test. | Effect of the CGRP-receptor antagonist CGRP(8-37)(~17 mm2) on the necrotic area in UV-damaged skin of the rat hindpaw compared to solvent applications(~25 mm2). | The dorsum of both hind paws were irradiated of male Sprague-Dawley (SD) rats. | 8584255 |
| 1256 | VTHRLAGLLSRSGGM VKSNFVPTNVGSKAF | CGRP receptor antagonist CGRP(8-37) | Regulation of blood flow, modulation of inflammation, and tissue remodelling | Photographed both hind paws using a micro-computer imaging device(MCID)-assessed analysis system. Immunostaining. Mann-Whitney U-test. | Effect of the CGRP-receptor antagonist CGRP(8-37)(~13 mm2) on the necrotic area in UV-damaged skin of the rat hindpaw compared to solvent applications(~16.5 mm2). | The dorsum of both hind paws were irradiated of male Sprague-Dawley (SD) rats. | 8584255 |
| 1257 | VTHRLAGLLSRSGGM VKSNFVPTNVGSKAF | CGRP receptor antagonist CGRP(8-37) | Regulation of blood flow, modulation of inflammation, and tissue remodelling | Photographed both hind paws using a micro-computer imaging device(MCID)-assessed analysis system. Immunostaining. Mann-Whitney U-test. | Effect of the CGRP-receptor antagonist CGRP(8-37)(~12 mm2) on the necrotic area in UV-damaged skin of the rat hindpaw compared to solvent applications(~14 mm2). | The dorsum of both hind paws were irradiated of male Sprague-Dawley (SD) rats. | 8584255 |
| 1258 | VTHRLAGLLSRSGGM VKSNFVPTNVGSKAF | CGRP receptor antagonist CGRP(8-37) | Regulation of blood flow, modulation of inflammation, and tissue remodelling | Photographed both hind paws using a micro-computer imaging device(MCID)-assessed analysis system. Immunostaining. Mann-Whitney U-test. | Effect of the CGRP-receptor antagonist CGRP(8-37)(~7 mm2) on the necrotic area in UV-damaged skin of the rat hindpaw compared to solvent applications(~13.5 mm2). | The dorsum of both hind paws were irradiated of male Sprague-Dawley (SD) rats. | 8584255 |
| 1267 | HSDAVFTDNYTRLR KQMAVKKYLNSILN | Stearyl-VIP | A key penile neurotransmitter, induces erection after local injection in man. Significantly increased sexual function as measured by copulatory activity and penile reflexes(erections) in testosterone-treated, castrated rats. | Radioactive assay, Measurement of number of cups | Measurement of number of cups: Control:1.5 , Test:3 | In castrated testosterone treated rats | 8156912 |
| 1268 | HSDAVFTDNYTRLR KQMAVKKYLNSILN | Stearyl-VIP | A key penile neurotransmitter, induces erection after local injection in man. Significantly increased sexual function as measured by copulatory activity and penile reflexes(erections) in testosterone-treated, castrated rats. | Radioactive assay, Measurement of number of cups | Measurement of number of cups: Control:4 , Test:9 | In castrated testosterone treated rats | 8156912 |
| 1269 | HSDAVFTDNYTRLR KQMAVKKYLNSILN | Stearyl-VIP | A key penile neurotransmitter, induces erection after local injection in man. Significantly increased sexual function as measured by copulatory activity and penile reflexes(erections) in testosterone-treated, castrated rats. | Radioactive assay, Measurement of number of cups | Measurement of number of cups: Control:4.5 , Test:7.5 | In castrated testosterone treated rats | 8156912 |
| 1270 | HSDAVFTDNYTRLR KQMAVKKYLNSILN | Stearyl-VIP | A key penile neurotransmitter, induces erection after local injection in man. Significantly increased sexual function as measured by copulatory activity and penile reflexes(erections) in testosterone-treated, castrated rats. | Radioactive assay, Measurement of number of cups | Measurement of number of cups: Control:7 , Test:15 | In castrated testosterone treated rats | 8156912 |
| 1271 | HSDAVFTDNYTRLR KQMAVKKYLNSILN | Stearyl-VIP | A key penile neurotransmitter, induces erection after local injection in man. Significantly increased sexual function as measured by copulatory activity and penile reflexes(erections) in testosterone-treated, castrated rats. | Radioactive assay, Measurement of E2(Erection) | Measurement of E2(Erection): Control:15 , Test:26 | In castrated testosterone treated rats | 8156912 |
| 1272 | HSDAVFTDNYTRLR KQMAVKKYLNSILN | Stearyl-VIP | A key penile neurotransmitter, induces erection after local injection in man. Significantly increased sexual function as measured by copulatory activity and penile reflexes(erections) in testosterone-treated, castrated rats. | Radioactive assay, Measurement of E2(Erection) | Measurement of E2(Erection): Control:4 , Test:11 | In castrated testosterone treated rats | 8156912 |
| 1273 | HSDAVFTDNYTRLR KQMAVKKYLNSILN | Stearyl-VIP | A key penile neurotransmitter, induces erection after local injection in man. Significantly increased sexual function as measured by copulatory activity and penile reflexes(erections) in testosterone-treated, castrated rats. | Radioactive assay, Measurement of E2(Erection) | Measurement of E2(Erection): Control:6 , Test:12 | In castrated testosterone treated rats | 8156912 |
| 1274 | HSDAVFTDNYTRLR KQMAVKKYLNSILN | Stearyl-VIP | A key penile neurotransmitter, induces erection after local injection in man. Significantly increased sexual function as measured by copulatory activity and penile reflexes(erections) in testosterone-treated, castrated rats. | Radioactive assay, Measurement of E2(Erection) | Measurement of E2(Erection): Control:11 , Test:24 | In castrated testosterone treated rats | 8156912 |
| 1275 | HSDAVFTDNYTRLR KQMAVKKYLNSILN | Stearyl-VIP | A key penile neurotransmitter, induces erection after local injection in man. Significantly increased sexual function as measured by copulatory activity and penile reflexes(erections) in testosterone-treated, castrated rats. | Radioactive assay, Measurement of latency of first cup | Measurement of latency of first cup: Control:44 minutes , Test:38 minutes | In castrated testosterone treated rats | 8156912 |
| 1276 | HSDAVFTDNYTRLR KQMAVKKYLNSILN | Stearyl-VIP | A key penile neurotransmitter, induces erection after local injection in man. Significantly increased sexual function as measured by copulatory activity and penile reflexes(erections) in testosterone-treated, castrated rats. | Radioactive assay, Measurement of latency of first cup | Measurement of latency of first cup: Control:25.5 minutes , Test:19 minutes | In castrated testosterone treated rats | 8156912 |
| 1277 | HSDAVFTDNYTRLR KQMAVKKYLNSILN | Stearyl-VIP | A key penile neurotransmitter, induces erection after local injection in man. Significantly increased sexual function as measured by copulatory activity and penile reflexes(erections) in testosterone-treated, castrated rats. | Radioactive assay, Measurement of latency of first cup | Measurement of latency of first cup: Control:39 minutes , Test:32 minutes | In castrated testosterone treated rats | 8156912 |
| 1278 | HSDAVFTDNYTRLR KQMAVKKYLNSILN | Stearyl-VIP | A key penile neurotransmitter, induces erection after local injection in man. Significantly increased sexual function as measured by copulatory activity and penile reflexes(erections) in testosterone-treated, castrated rats. | Radioactive assay, Measurement of latency of first cup | Measurement of latency of first cup: Control:23 minutes , Test:15 minutes | In castrated testosterone treated rats | 8156912 |
| 1279 | HSDAVFTDNYTRLR KQMAVKKYLNSILN | Stearyl-VIP | A key penile neurotransmitter, induces erection after local injection in man. Significantly increased sexual function as measured by copulatory activity and penile reflexes(erections) in testosterone-treated, castrated rats. | Radioactive assay, Measurement of latency of first E2(Erection) | Measurement of latency of first E2(Erection): Control:29 minutes , Test:31 minutes | In castrated testosterone treated rats | 8156912 |
| 1280 | HSDAVFTDNYTRLR KQMAVKKYLNSILN | Stearyl-VIP | A key penile neurotransmitter, induces erection after local injection in man. Significantly increased sexual function as measured by copulatory activity and penile reflexes(erections) in testosterone-treated, castrated rats. | Radioactive assay, Measurement of latency of first E2(Erection) | Measurement of latency of first E2(Erection): Control:32 minutes , Test:16 minutes | In castrated testosterone treated rats | 8156912 |
| 1281 | HSDAVFTDNYTRLR KQMAVKKYLNSILN | Stearyl-VIP | A key penile neurotransmitter, induces erection after local injection in man. Significantly increased sexual function as measured by copulatory activity and penile reflexes(erections) in testosterone-treated, castrated rats. | Radioactive assay, Measurement of latency of first E2(Erection) | Measurement of latency of first E2(Erection): Control:9 minutes , Test:3 minutes | In castrated testosterone treated rats | 8156912 |
| 1282 | HSDAVFTDNYTRLR KQMAVKKYLNSILN | Stearyl-VIP | A key penile neurotransmitter, induces erection after local injection in man. Significantly increased sexual function as measured by copulatory activity and penile reflexes(erections) in testosterone-treated, castrated rats. | Radioactive assay, Measurement of latency of first E2(Erection) | Measurement of latency of first E2(Erection): Control:3.5 minutes , Test:2 minutes | In castrated testosterone treated rats | 8156912 |
| 1283 | HSDAVFTDNYTRLR KQ-Nle-AVKKYLNSILN | Stearyl-Nle17- VIP | A key penile neurotransmitter, induces erection after local injection in man. Significantly increased sexual function as measured by copulatory activity and penile reflexes(erections) in testosterone-treated, castrated rats. | Radioactive assay, Measurement of number of cups | Measurement of number of first cup: Control:7 minutes , Test:20.2 minutes | In castrated testosterone treated rats | 8156912 |
| 1284 | HSDAVFTDNYTRLR KQ-Nle-AVKKYLNSILN | Stearyl-Nle17- VIP | A key penile neurotransmitter, induces erection after local injection in man. Significantly increased sexual function as measured by copulatory activity and penile reflexes(erections) in testosterone-treated, castrated rats. | Radioactive assay, Measurement of E2(Erection) | Measurement of number of first E2(Erection): Control:11 minutes , Test:35 minutes | In castrated testosterone treated rats | 8156912 |
| 1285 | HSDAVFTDNYTRLR KQ-Nle-AVKKYLNSILN | Stearyl-Nle17- VIP | A key penile neurotransmitter, induces erection after local injection in man. Significantly increased sexual function as measured by copulatory activity and penile reflexes(erections) in testosterone-treated, castrated rats. | Radioactive assay, Measurement of latency of first cup | Measurement of latency of first cup: Control:23 minutes , Test:10 minutes | In castrated testosterone treated rats | 8156912 |
| 1286 | HSDAVFTDNYTRLR KQ-Nle-AVKKYLNSILN | Stearyl-Nle17- VIP | A key penile neurotransmitter, induces erection after local injection in man. Significantly increased sexual function as measured by copulatory activity and penile reflexes(erections) in testosterone-treated, castrated rats. | Radioactive assay, Measurement of latency of first E2(Erection) | Measurement of latency of first E2(Erection): Control:3.5 minutes , Test:1.9 minutes | In castrated testosterone treated rats | 8156912 |
| 1287 | HSDAVFTDNYTRLR KQ-Nle-AVKKYLNSILN | Stearyl-Nle17- VIP | A key penile neurotransmitter, induces erection after local injection in man. Significantly increased sexual function as measured by copulatory activity and penile reflexes(erections) in testosterone-treated, castrated rats. | Radioactive assay | Time course of distribution of radioactively labelled peptide: Control:6 minutes , Test:20 minutes | Three-month-old diabetic rats | 8156912 |
| 1288 | HSDAVFTDNYTRLR KQ-Nle-AVKKYLNSILN | Stearyl-Nle17- VIP | A key penile neurotransmitter, induces erection after local injection in man. Significantly increased sexual function as measured by copulatory activity and penile reflexes(erections) in testosterone-treated, castrated rats. | Radioactive assay | Time course of distribution of radioactively labelled peptide:Control:5.5 minutes , Test:21.5 minutes | Spontaneous high blood pressure rats(SHR) | 8156912 |
| 1348 | HSDAVFTDNYTRLR KQMAVKKYLNSILN | Vasoactive intestinal peptide (VIP) | A key penile neurotransmitter, induces erection after local injection in man. | Labelled peptide was detected and quantified by measuring radioactivity in a gamma counter | 0.6% of the applied material was found in the penile tissue | Rats with reduced sexual potential due to castration were employed for topical application on their penile organ. | 1522236 |
| 1349 | HSDAVFTDNYTRLR KQMAVKKYLNSILN | Stearyl-VIP | A key penile neurotransmitter, induces erection after local injection in man. Significantly increased sexual function as measured by copulatory activity and penile reflexes(erections) in testosterone-treated, castrated rats. | Labelled peptide was detected and quantified by measuring radioactivity in a gamma counter | 5% of the applied material was found in the penile tissue | Rats with reduced sexual potential due to castration were employed for topical application on their penile organ. | 1522236 |
| 1350 | HSDAVFTDNYTRLR KQMAVKKYLNSILN | Stearyl-VIP | A key penile neurotransmitter, induces erection after local injection in man. Significantly increased sexual function as measured by copulatory activity and penile reflexes(erections) in testosterone-treated, castrated rats. | Labelled peptide was detected and quantified by measuring radioactivity in a gamma counter | 2.5% of the applied material was found in the penile tissue | Rats with reduced sexual potential due to castration were employed for topical application on their penile organ. | 1522236 |
| 1351 | HSDAVFTDNYTRLR KQMAVKKYLNSILN | Stearyl-VIP | A key penile neurotransmitter, induces erection after local injection in man. Significantly increased sexual function as measured by copulatory activity and penile reflexes(erections) in testosterone-treated, castrated rats. | Labelled peptide was detected and quantified by measuring radioactivity in a gamma counter | 1.25% of the applied material was found in the penile tissue | Rats with reduced sexual potential due to castration were employed for topical application on their penile organ. | 1522236 |
| 1352 | HSDAVFTDNYTRLR KQMAVKKYLNSILN | Stearyl-VIP | A key penile neurotransmitter, induces erection after local injection in man. Significantly increased sexual function as measured by copulatory activity and penile reflexes(erections) in testosterone-treated, castrated rats. | Radiolabelling assay is used to determine incorporation per 10 ml blood as a percentage of the total radioactivity applied using gamma counter. | Approximately 0.6% incorporation per 10 ml blood as a percentage of the total radioactivity applied | Rats with reduced sexual potential due to castration were employed for topical application on their penile organ to check sytemic dispersion. | 1522236 |
| 1353 | HSDAVFTDNYTRLR KQMAVKKYLNSILN | Stearyl-VIP | A key penile neurotransmitter, induces erection after local injection in man. Significantly increased sexual function as measured by copulatory activity and penile reflexes(erections) in testosterone-treated, castrated rats. | Radiolabelling assay is used to determine incorporation per 10 ml blood as a percentage of the total radioactivity applied using gamma counter. | Approximately 0.55% incorporation per 10 ml blood as a percentage of the total radioactivity applied | Rats with reduced sexual potential due to castration were employed for topical application on their penile organ to check sytemic dispersion. | 1522236 |
| 1354 | HSDAVFTDNYTRLR KQMAVKKYLNSILN | Stearyl-VIP | A key penile neurotransmitter, induces erection after local injection in man. Significantly increased sexual function as measured by copulatory activity and penile reflexes(erections) in testosterone-treated, castrated rats. | Radiolabelling assay is used to determine incorporation per 10 ml blood as a percentage of the total radioactivity applied using gamma counter. | Approximately 0.4% incorporation per 10 ml blood as a percentage of the total radioactivity applied | Rats with reduced sexual potential due to castration were employed for topical application on their penile organ to check sytemic dispersion. | 1522236 |
| 1380 | SKYALVDASLKMSDP NRFRGKDLPVLDQL | HSV-1 gD 1-29 (group1) | Intranasal aministration of HSV-gD peptides plus CpG can induce local ocular mucosal and systemic T-cell responses | FACS | Detectable HSV-1-specific CD4+ T cell responses were induced at the local (conjunctiva) and systemic (spleen) levels. | Nasal cavity of New Zealand White rabbits | 20089796 |
| 1383 | APQIVRGASEDVRK QPYNLTIAWFRMGG | HSV-1 gD 77-104 (group-1) | Intranasal aministration of HSV-gD peptides plus CpG can induce local ocular mucosal and systemic T-cell responses | FACS | Detectable HSV-1-specific CD4+ T cell responses were induced at the local (conjunctiva) and systemic (spleen) levels. | Nasal cavity of New Zealand White rabbits | 20089796 |
| 1384 | TIAWFRMGGNCAIP ITVMEYTECSYNKS | HSV-1 gD 96-123 (group 3) | Intranasal aministration of HSV-gD peptides plus CpG can induce local ocular mucosal and systemic T-cell responses | FACS | Detectable HSV-1-specific CD4+ T cell responses were induced at the local (conjunctiva) and systemic (spleen) levels | Nasal cavity of New Zealand White rabbits | 20089796 |
| 1389 | QRTVAVYSLKIAGWH GPKAPYTSTLLPPEL | HSV-1 gD 228-257(group-3) | Intranasal aministration of HSV-gD peptides plus CpG can induce local ocular mucosal and systemic T-cell responses | FACS | Detectable HSV-1-specific CD4+ T cell responses were induced at the local (conjunctiva) and systemic (spleen) levels | Nasal cavity of New Zealand White rabbits | 20089796 |
| 1390 | ICGIVYWMRRHTQKA PKRIRLPHIRED | HSV-1 gD 332-358 (group-3) | Intranasal aministration of HSV-gD peptides plus CpG can induce local ocular mucosal and systemic T-cell responses | FACS | Detectable HSV-1-specific CD4+ T cell responses were induced at the local (conjunctiva) and systemic (spleen) levels | Nasal cavity of New Zealand White rabbits | 20089796 |
| 1425 | HSDAVFTDNYTRLR KQMAVKKYLNSILN | Vasoactive intestinal peptide (VIP) | Potent cAMP-dependent stimulus of both fluid and protein secretion from the rat and rabbit main lacrimal gland | Tear film osmolarity | Osmolarity measurements: t=0 min., VIP/Buffer=330/314.5mOsm/l; t=16 min., VIP/Buffer=315/313.5mOsm/l | Eyes of male and female New Zealand white rabbits with closed lacrimal gland excretory duct | 2365569 |
| 1426 | HSDAVFTDNYTRLR KQMAVKKYLNSILN | Vasoactive intestinal peptide (VIP) | Potent cAMP-dependent stimulus of both fluid and protein secretion from the rat and rabbit main lacrimal gland | Tear film osmolarity | Osmolarity measurements: t=0 min., VIP/Buffer=320/318mOsm/l; t=6 min., VIP/Buffer=303.5/310mOsm/l; t=16 min., VIP/Buffer=310/314mOsm/l | Eyes of male and female New Zealand white rabbits with closed lacrimal gland excretory duct | 2365569 |
| 1427 | HSDAVFTDNYTRLR KQMAVKKYLNSILN | Vasoactive intestinal peptide (VIP) | Potent cAMP-dependent stimulus of both fluid and protein secretion from the rat and rabbit main lacrimal gland | Osmolarity and tear volume measurements | Osmolarity measurements: t=0 min., VIP/Buffer=315/320mOsm/l; t=6 min., VIP/Buffer=301/314mOsm/l; t=16 min., VIP/Buffer=308/313mOsm/l; Volume measurement: VIP/Buffer= 17µl/7µl | Eyes of male and female New Zealand white rabbits with closed lacrimal gland excretory duct | 2365569 |
| 1428 | HSDGTLTSELSRLRD RARLQRLLQGLL | Secretin | Secretin stimulates the release of a watery bicarbonate solution from the pancreatic and bile duct epithelium. | Tear film osmolarity | Caused decrease in tear film osmolarity | Eyes of male and female New Zealand white rabbits with closed lacrimal gland excretory duct | 2365569 |
| 1429 | HSDGTLTSELSRLRD RARLQRLLQGLL | Secretin | Secretin stimulates the release of a watery bicarbonate solution from the pancreatic and bile duct epithelium. | Tear film osmolarity | Caused decrease in tear film osmolarity | Eyes of male and female New Zealand white rabbits with closed lacrimal gland excretory duct | 2365569 |
| 1430 | HSDGTLTSELSRLRD RARLQRLLQGLL | Secretin | Secretin stimulates the release of a watery bicarbonate solution from the pancreatic and bile duct epithelium. | Osmolarity and tear volume measurements | Caused decrease in tear film osmolarity, Tear volume: VIP/Buffer= 5.0±0.8µl/5.5±0.5µl | Eyes of male and female New Zealand white rabbits with closed lacrimal gland excretory duct | 2365569 |
| 1431 | HSQGTFTSDYSKYLD SRRAQDFVQWLMNT | Glucagon | The pancreas releases glucagon when the concentration of glucose in the bloodstream falls too low in order to raise glucose levels | Tear film osmolarity | Osmolarity measurements: t=0 min., Glucagon/Buffer=311/312.5mOsm/l; t=6 min., Glucagon/Buffer=304/306.5mOsm/l; t=16 min., Glucagon/Buffer=305/307.5mOsm/l | Eyes of male and female New Zealand white rabbits with closed lacrimal gland excretory duct | 2365569 |
| 1432 | HSQGTFTSDYSKYLD SRRAQDFVQWLMNT | Glucagon | The pancreas releases glucagon when the concentration of glucose in the bloodstream falls too low in order to raise glucose levels | Osmolarity and tear volume measurements | Osmolarity measurements: t=0 min., Glucagon/Buffer=310/308mOsm/l; t=6 min., Glucagon/Buffer=301/306mOsm/l; t=16 min., Glucagon/Buffer=305/307mOsm/l; Volume measurement: Glucagon/Buffer= 11.5µl/5.2µl | Eyes of male and female New Zealand white rabbits with closed lacrimal gland excretory duct | 2365569 |
| 1503 | SKYALVDASLKMADP NRFRGKDLPVLDQL | gD 1-29 (group 1) | not mentioned | ELISA, Antibody assay, Peptide specific T-cell assays | Failed to induce significant IgA titers (p > 1). | eye | 15603887 |